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3W3X
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Crystal structure of Kap121p bound to Pho4p
Descriptor: Importin subunit beta-3, Phosphate system positive regulatory protein PHO4
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
3W3W
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Crystal structure of Kap121p bound to Ste12p
Descriptor: Importin subunit beta-3, Protein STE12
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
3W3Y
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BU of 3w3y by Molmil
Crystal structure of Kap121p bound to Nup53p
Descriptor: Importin subunit beta-3, Nucleoporin NUP53
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
3W3T
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BU of 3w3t by Molmil
Crystal structure of Kap121p
Descriptor: Importin subunit beta-3
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
3W3V
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BU of 3w3v by Molmil
Crystal structure of Kap121p mutant D353K/E396K/D438K
Descriptor: Importin subunit beta-3
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
3W3U
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BU of 3w3u by Molmil
Crystal structure of Kap121p mutant R349A/Q350A/D353A/E396A/N430K/D438A/N477A
Descriptor: Importin subunit beta-3
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
4JLQ
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BU of 4jlq by Molmil
Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2
Descriptor: Nuclear polyadenylated RNA-binding protein NAB2, Transportin-1
Authors:Sampathkumar, P, Gizzi, A, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
Deposit date:2013-03-12
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of human Karyopherin beta 2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
J.Struct.Funct.Genom., 14, 2013
4OL0
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BU of 4ol0 by Molmil
Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tsirkone, V.G, Strelkov, S.V.
Deposit date:2014-01-23
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran.
Acta Crystallogr.,Sect.F, 70, 2014
5MFM
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BU of 5mfm by Molmil
Designed armadillo repeat protein peptide fusion YIIIM6AII_GS11_(KR)5
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Importin subunit alpha, ...
Authors:Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A.
Deposit date:2016-11-18
Release date:2017-09-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Curvature of designed armadillo repeat proteins allows modular peptide binding.
J. Struct. Biol., 201, 2018
1WA5
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BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
Authors:Stewart, M.
Deposit date:2004-10-23
Release date:2004-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
2VY6
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BU of 2vy6 by Molmil
Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit
Descriptor: POLYMERASE BASIC PROTEIN 2
Authors:Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D.
Deposit date:2008-07-18
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
7YJI
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BU of 7yji by Molmil
Crystal structure of Lpg1083 from Legionella pneumophila
Descriptor: ACETATE ION, T4SS effector Lpg1083
Authors:Ge, H, Gao, J, Chen, X.
Deposit date:2022-07-20
Release date:2023-06-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The bacterial effector SidN/Lpg1083 promotes cell death by targeting Lamin-B2.
J Mol Cell Biol, 15, 2023
7CYL
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BU of 7cyl by Molmil
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Chook, Y.M.
Deposit date:2020-09-03
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Sci Rep, 11, 2021
2GMO
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BU of 2gmo by Molmil
NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2
Descriptor: Polymerase basic protein 2
Authors:Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J.
Deposit date:2006-04-07
Release date:2007-02-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nat.Struct.Mol.Biol., 14, 2007
3CH5
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BU of 3ch5 by Molmil
The crystal structure of the RanGDP-Nup153ZnF2 complex
Descriptor: Fragment of Nuclear pore complex protein Nup153, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Vetter, I.R, Schrader, N.
Deposit date:2008-03-07
Release date:2008-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of the Ran-Nup153ZnF2 Complex: a General Ran Docking Site at the Nuclear Pore Complex
Structure, 16, 2008
4U2X
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BU of 4u2x by Molmil
Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus
Descriptor: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24
Authors:Xu, W, Leung, D, Borek, D, Amarasinghe, G.
Deposit date:2014-07-18
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.153 Å)
Cite:Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1.
Cell Host Microbe, 16, 2014
1QBK
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BU of 1qbk by Molmil
STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX
Descriptor: KARYOPHERIN BETA2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Chook, Y.M, Blobel, G.
Deposit date:1999-04-23
Release date:1999-06-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.
Nature, 399, 1999
1EFX
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BU of 1efx by Molmil
STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3
Descriptor: BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ...
Authors:Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D.
Deposit date:2000-02-10
Release date:2000-06-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405, 2000
1BK6
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BU of 1bk6 by Molmil
KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
Descriptor: KARYOPHERIN ALPHA, LARGE T ANTIGEN
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1BK5
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BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
Descriptor: COBALT (II) ION, KARYOPHERIN ALPHA
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
5YVG
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BU of 5yvg by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVI
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BU of 5yvi by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVH
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BU of 5yvh by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
3W3Z
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BU of 3w3z by Molmil
Crystal structure of Kap121p bound to RanGTP
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-3, ...
Authors:Kobayashi, J, Matsuura, Y.
Deposit date:2012-12-28
Release date:2013-04-10
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
8SGH
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BU of 8sgh by Molmil
Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS
Descriptor: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1
Authors:Gonzalez, A, Fung, H.Y.J, Chook, Y.M.
Deposit date:2023-04-12
Release date:2023-06-14
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Structure, 31, 2023

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