5YVI

Crystal structure of Karyopherin beta2 in complex with FUS(456-526)

Summary for 5YVI

Entry DOI	10.2210/pdb5yvi/pdb
Descriptor	Transportin-1, RNA-binding protein FUS (2 entities in total)
Functional Keywords	importin family, protein transport, protein transport-rna binding protein complex, protein transport/rna binding protein
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: Q92973 Nucleus : P35637
Total number of polymer chains	2
Total formula weight	105886.39
Authors	Yoshizawa, T.,Fung, H.Y.J.,Chook, Y.M. (deposition date: 2017-11-25, release date: 2018-05-16, Last modification date: 2023-11-22)
Primary citation	Yoshizawa, T.,Ali, R.,Jiou, J.,Fung, H.Y.J.,Burke, K.A.,Kim, S.J.,Lin, Y.,Peeples, W.B.,Saltzberg, D.,Soniat, M.,Baumhardt, J.M.,Oldenbourg, R.,Sali, A.,Fawzi, N.L.,Rosen, M.K.,Chook, Y.M. Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173:693-705.e22, 2018 Cited by PubMed: 29677513 DOI: 10.1016/j.cell.2018.03.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation