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5YVI

Crystal structure of Karyopherin beta2 in complex with FUS(456-526)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATransportin-1polymer86898325.41UniProt (Q92973)
Pfam (PF03810)
Pfam (PF02985)
Pfam (PF13513)
In PDB
Homo sapiens (Human)Importin beta-2,Karyopherin beta-2,M9 region interaction protein,MIP
2BRNA-binding protein FUSpolymer737561.01UniProt (P35637)
In PDB
Homo sapiens (Human)75 kDa DNA-pairing protein,Oncogene FUS,Oncogene TLS,POMp75,Translocated in liposarcoma protein
Sequence modifications
A: 1 - 360 (UniProt: Q92973)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
A: 368 - 890 (UniProt: Q92973)
PDBExternal DatabaseDetails
Gly 361-linker
Gly 362-linker
Ser 363-linker
Gly 364-linker
Gly 365-linker
Ser 366-linker
Gly 367-linker
B: 456 - 526 (UniProt: P35637)
PDBExternal DatabaseDetails
Gly 454-expression tag
Ser 455-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight105886.4
All*Total formula weight105886.4
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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