4JLQ

Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2

Replaces:  4H1K

Summary for 4JLQ

DescriptorTransportin-1, Nuclear polyadenylated RNA-binding protein NAB2 (2 entities in total)
Functional Keywordsheat repeats, karyopherin, nuclear import, proteintransport, importin, transportin, transport protein, nls, nab2, structural genomics, nucleocytoplasmic transport: a target for cellular control (npcxstals), new york structural genomics research consortium (nysgrc), psi-biology, npcxstals
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm Q92973
Nucleus P32505
Total number of polymer chains2
Total molecular weight100790.23
Authors
Primary citation
Soniat, M.,Sampathkumar, P.,Collett, G.,Gizzi, A.S.,Banu, R.N.,Bhosle, R.C.,Chamala, S.,Chowdhury, S.,Fiser, A.,Glenn, A.S.,Hammonds, J.,Hillerich, B.,Khafizov, K.,Love, J.D.,Matikainen, B.,Seidel, R.D.,Toro, R.,Rajesh Kumar, P.,Bonanno, J.B.,Chook, Y.M.,Almo, S.C.
Crystal structure of human Karyopherin beta 2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
J.Struct.Funct.Genom., 14:31-35, 2013
PubMed: 23535894 (PDB entries with the same primary citation)
DOI: 10.1007/s10969-013-9150-1
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.05 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22960.7%1.3%0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload