3CHR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3chr by Molmil](/molmil-images/mine/3chr) | Crystal structure of leukotriene A4 hydrolase in complex with 4-amino-N-[4-(phenylmethoxy)phenyl]-butanamide | Descriptor: | 4-amino-N-[4-(benzyloxy)phenyl]butanamide, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | Authors: | Thunnissen, M.M.G.M, Adler, M, Whitlow, M. | Deposit date: | 2008-03-10 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase. Bioorg.Med.Chem., 16, 2008
|
|
3CZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3czd by Molmil](/molmil-images/mine/3czd) | Crystal structure of human glutaminase in complex with L-glutamate | Descriptor: | GLUTAMIC ACID, GLYCEROL, Glutaminase kidney isoform, ... | Authors: | Karlberg, T, Welin, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-04-29 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3CHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3chs by Molmil](/molmil-images/mine/3chs) | Crystal structure of leukotriene A4 hydrolase in complex with (2S)-2-amino-5-[[4-[(2S)-2-hydroxy-2-phenyl-ethoxy]phenyl]amino]-5-oxo-pentanoic acid | Descriptor: | (2S)-2-amino-5-[[4-[(2S)-2-hydroxy-2-phenyl-ethoxy]phenyl]amino]-5-oxo-pentanoic acid, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | Authors: | Thunnissen, M.M.G.M, Adler, M, Whitlow, M. | Deposit date: | 2008-03-10 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase. Bioorg.Med.Chem., 16, 2008
|
|
3CP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cp7 by Molmil](/molmil-images/mine/3cp7) | |
1XGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xgv by Molmil](/molmil-images/mine/1xgv) | Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix | Descriptor: | Isocitrate dehydrogenase | Authors: | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | Deposit date: | 2004-09-17 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability J.Mol.Biol., 345, 2005
|
|
1W6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1w6h by Molmil](/molmil-images/mine/1w6h) | Novel plasmepsin II-inhibitor complex | Descriptor: | N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE, PLASMEPSIN 2 | Authors: | Lindberg, J, Johansson, P.-O, Rosenquist, A, Kvarnstroem, I, Vrang, L, Samuelsson, B, Unge, T. | Deposit date: | 2004-08-18 | Release date: | 2006-07-05 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design To be Published
|
|
1W4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1w4y by Molmil](/molmil-images/mine/1w4y) | Ferrous horseradish peroxidase C1A in complex with carbon monoxide | Descriptor: | CALCIUM ION, CARBON MONOXIDE, HORSERADISH PEROXIDASE C1A, ... | Authors: | Carlsson, G.H, Nicholls, P, Svistunenko, D, Berglund, G.I, Hajdu, J. | Deposit date: | 2004-08-03 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Complexes of Horseradish Peroxidase with Formate, Acetate, and Carbon Monoxide Biochemistry, 44, 2005
|
|
1WBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wbk by Molmil](/molmil-images/mine/1wbk) | |
1W6I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1w6i by Molmil](/molmil-images/mine/1w6i) | plasmepsin II-pepstatin A complex | Descriptor: | PEPSTATIN, PLASMEPSIN 2 PRECURSOR | Authors: | Lindberg, J, Johansson, P.-O, Rosenquist, A, Kvarnstroem, I, Vrang, L, Samuelsson, B, Unge, T. | Deposit date: | 2004-08-18 | Release date: | 2006-07-05 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design To be Published
|
|
6V5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v5d by Molmil](/molmil-images/mine/6v5d) | EROS3 RDC and NOE Derived Ubiquitin Ensemble | Descriptor: | Ubiquitin | Authors: | Lange, O.F, Lakomek, N.A, Smith, C.A, Griesinger, C, de Groot, B.L. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Enhancing NMR derived ensembles with kinetics on multiple timescales. J.Biomol.Nmr, 74, 2020
|
|
1WB7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wb7 by Molmil](/molmil-images/mine/1wb7) | Iron Superoxide Dismutase (Fe-SOD) From The Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F mutant. | Descriptor: | FE (III) ION, SUPEROXIDE DISMUTASE [FE] | Authors: | Gogliettino, M.A, Tanfani, F, Scire, A, Ursby, T, Adinolfi, B.S, Cacciamani, T, De Vendittis, E. | Deposit date: | 2004-10-31 | Release date: | 2004-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | The Role of Tyr41 and His155 in the Functional Properties of Superoxide Dismutase from the Archaeon Sulfolobus Solfataricus Biochemistry, 43, 2004
|
|
1W4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1w4w by Molmil](/molmil-images/mine/1w4w) | Ferric horseradish peroxidase C1A in complex with formate | Descriptor: | CALCIUM ION, FORMIC ACID, HORSERADISH PEROXIDASE C1A, ... | Authors: | Carlsson, G.H, Nicholls, P, Svistunenko, D, Berglund, G.I, Hajdu, J. | Deposit date: | 2004-08-03 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Complexes of Horseradish Peroxidase with Formate, Acetate, and Carbon Monoxide Biochemistry, 44, 2005
|
|
1YM3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ym3 by Molmil](/molmil-images/mine/1ym3) | Crystal Structure of carbonic anhydrase RV3588c from Mycobacterium tuberculosis | Descriptor: | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), MAGNESIUM ION, ZINC ION | Authors: | Covarrubias, A.S, Larsson, A.M, Hogbom, M, Lindberg, J, Bergfors, T, Bjorkelid, C, Mowbray, S.L, Unge, T, Jones, T.A, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-01-20 | Release date: | 2005-03-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and function of carbonic anhydrases from Mycobacterium tuberculosis. J.Biol.Chem., 280, 2005
|
|
1XJK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjk by Molmil](/molmil-images/mine/1xjk) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-11-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
|
|
1XJF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjf by Molmil](/molmil-images/mine/1xjf) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
|
|
1XKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xkd by Molmil](/molmil-images/mine/1xkd) | Ternary complex of Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix | Descriptor: | CALCIUM ION, ISOCITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | Deposit date: | 2004-09-28 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability. J.Mol.Biol., 345, 2005
|
|
1ZCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zcj by Molmil](/molmil-images/mine/1zcj) | |
1ZKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zkr by Molmil](/molmil-images/mine/1zkr) | Crystal structure of the major cat allergen Fel d 1 (1+2) | Descriptor: | Major allergen I polypeptide, fused chain 1, chain 2 | Authors: | Kaiser, L, Cirkovic Velickovic, T, Adedoyin, J, Thunberg, S, Gronlund, H, Gafvelin, G, van Hage, M, Achour, A. | Deposit date: | 2005-05-04 | Release date: | 2006-05-16 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal structure of the major cat allergen Fel d 1 (1+2) To be Published
|
|
1XSE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xse by Molmil](/molmil-images/mine/1xse) | Crystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1 | Descriptor: | 11beta-hydroxysteroid dehydrogenase type 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Ogg, D, Elleby, B, Norstrom, C, Stefansson, K, Abrahmsen, L, Oppermann, U, Svensson, S. | Deposit date: | 2004-10-19 | Release date: | 2004-11-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions J.Biol.Chem., 280, 2005
|
|
1XMZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xmz by Molmil](/molmil-images/mine/1xmz) | Crystal structure of the dark state of kindling fluorescent protein kfp from anemonia sulcata | Descriptor: | BETA-MERCAPTOETHANOL, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Quillin, M.L, Anstrom, D.M, Shu, X, O'Leary, S, Kallio, K, Chudakov, D.M, Remington, S.J. | Deposit date: | 2004-10-04 | Release date: | 2005-04-19 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Kindling Fluorescent Protein from Anemonia sulcata: Dark-State Structure at 1.38 Resolution Biochemistry, 44, 2005
|
|
1XJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xjj by Molmil](/molmil-images/mine/1xjj) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ribonucleotide reductase, ... | Authors: | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | Deposit date: | 2004-09-23 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol., 11, 2005
|
|
1XWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xwg by Molmil](/molmil-images/mine/1xwg) | Human GST A1-1 T68E mutant | Descriptor: | Glutathione S-transferase A1 | Authors: | Grahn, E, Jakobsson, E, Gustafsson, A, Novotny, M, Grehn, L, Olin, B, Madsen, D, Wahlberg, M, Mannervik, B, Kleywegt, G.J. | Deposit date: | 2004-11-01 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix. Acta Crystallogr.,Sect.D, 62, 2006
|
|
1Z43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z43 by Molmil](/molmil-images/mine/1z43) | |
1XS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xs4 by Molmil](/molmil-images/mine/1xs4) | dCTP deaminase from Escherichia coli- E138A mutant enzyme in complex with dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION | Authors: | Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. | Deposit date: | 2004-10-18 | Release date: | 2004-12-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
|
|
1ZJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zj8 by Molmil](/molmil-images/mine/1zj8) | Structure of Mycobacterium tuberculosis NirA protein | Descriptor: | CHLORIDE ION, IRON/SULFUR CLUSTER, Probable ferredoxin-dependent nitrite reductase NirA, ... | Authors: | Schnell, R, Sandalova, T, Hellman, U, Lindqvist, Y, Schneider, G, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-04-28 | Release date: | 2005-05-31 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis Is a Sulfite Reductase with a Covalent Cys-Tyr Bond in the Active Site J.Biol.Chem., 280, 2005
|
|