1W6I

plasmepsin II-pepstatin A complex

Summary for 1W6I

• Entry DOI: 10.2210/pdb1w6i/pdb
• Related: 1J8J 1LEE 1LF2 1LF3 1LF4 1M43 1ME6 1PFZ 1SME 1W6H 1XDH 1XE5 1XE6 2BJU 2BL3
• Related PRD ID: PRD_000557
• Descriptor: PLASMEPSIN 2 PRECURSOR, PEPSTATIN (3 entities in total)
• Functional Keywords: malaria, drug, aspartic protease, plasmepsin, glycoprotein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: PLASMODIUM FALCIPARUM; More
• Cellular location: Vacuole: P46925
• Total number of polymer chains: 4
• Total formula weight: 75619.66

Authors

Lindberg, J.,Johansson, P.-O.,Rosenquist, A.,Kvarnstroem, I.,Vrang, L.,Samuelsson, B.,Unge, T. (deposition date: 2004-08-18, release date: 2006-07-05, Last modification date: 2024-11-20)

• Primary citation: Lindberg, J.,Johansson, P.-O.,Rosenquist, A.,Kvarnstroem, I.,Vrang, L.,Samuelsson, B.,Unge, T.; Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design; To be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)