1W6I
plasmepsin II-pepstatin A complex
Summary for 1W6I
Entry DOI | 10.2210/pdb1w6i/pdb |
Related | 1J8J 1LEE 1LF2 1LF3 1LF4 1M43 1ME6 1PFZ 1SME 1W6H 1XDH 1XE5 1XE6 2BJU 2BL3 |
Related PRD ID | PRD_000557 |
Descriptor | PLASMEPSIN 2 PRECURSOR, PEPSTATIN (3 entities in total) |
Functional Keywords | malaria, drug, aspartic protease, plasmepsin, glycoprotein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | PLASMODIUM FALCIPARUM More |
Cellular location | Vacuole: P46925 |
Total number of polymer chains | 4 |
Total formula weight | 75619.66 |
Authors | Lindberg, J.,Johansson, P.-O.,Rosenquist, A.,Kvarnstroem, I.,Vrang, L.,Samuelsson, B.,Unge, T. (deposition date: 2004-08-18, release date: 2006-07-05, Last modification date: 2018-01-17) |
Primary citation | Lindberg, J.,Johansson, P.-O.,Rosenquist, A.,Kvarnstroem, I.,Vrang, L.,Samuelsson, B.,Unge, T. Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design To be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report