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PDB: 103 results

6Y0G
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BU of 6y0g by Molmil
Structure of human ribosome in classical-PRE state
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
Deposit date:2020-02-07
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6LSS
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BU of 6lss by Molmil
Cryo-EM structure of a pre-60S ribosomal subunit - state preA
Descriptor: 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-20
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
8Y0X
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BU of 8y0x by Molmil
Dormant ribosome with SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The global structure of dormant ribosome
To Be Published
8IE3
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BU of 8ie3 by Molmil
human nuclear pre-60S ribosomal particle - State E
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-02-15
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8IR1
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BU of 8ir1 by Molmil
human nuclear pre-60S ribosomal particle - State A
Descriptor: 28S rRNA, 5.8S rRMA, 5S RNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-03-17
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
7BHP
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BU of 7bhp by Molmil
Cryo-EM structure of the human Ebp1 - 80S ribosome
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Desogus, J, Bhaskar, V, Chao, J.A.
Deposit date:2021-01-11
Release date:2021-02-03
Last modified:2021-03-31
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Dynamic association of human Ebp1 with the ribosome.
Rna, 27, 2021
8OJ8
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BU of 8oj8 by Molmil
60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R.
Deposit date:2023-03-24
Release date:2024-02-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
8OJ0
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BU of 8oj0 by Molmil
60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R.
Deposit date:2023-03-23
Release date:2024-02-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:dormant ribosome with eIF5A, eEF2 and SERBP1
To Be Published
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6ZVK
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BU of 6zvk by Molmil
The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ...
Authors:Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-07-24
Release date:2020-12-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
8IR3
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BU of 8ir3 by Molmil
human nuclear pre-60S ribosomal particle - State B'
Descriptor: 28S rRNA, 5.8S rRNA, 5S RNA, ...
Authors:Zhang, Y, Gao, N.
Deposit date:2023-03-17
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
5AJ0
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BU of 5aj0 by Molmil
Cryo electron microscopy of actively translating human polysomes (POST state).
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-02-19
Release date:2015-05-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
6Y57
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BU of 6y57 by Molmil
Structure of human ribosome in hybrid-PRE state
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
Deposit date:2020-02-25
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
5LKS
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BU of 5lks by Molmil
Structure-function insights reveal the human ribosome as a cancer target for antibiotics
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P.
Deposit date:2016-07-23
Release date:2017-04-26
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure-function insights reveal the human ribosome as a cancer target for antibiotics.
Nat Commun, 7, 2016
5T2C
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BU of 5t2c by Molmil
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Zhang, X, Lai, M, Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
7A01
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BU of 7a01 by Molmil
The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ...
Authors:Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-08-05
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
4UG0
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BU of 4ug0 by Molmil
STRUCTURE OF THE HUMAN 80S RIBOSOME
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ...
Authors:Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P.
Deposit date:2015-03-20
Release date:2015-06-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the human 80S ribosome
NATURE, 520, 2015
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-18
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6W6L
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BU of 6w6l by Molmil
Cryo-EM structure of the human ribosome-TMCO1 translocon
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Keenan, R.J, McGilvray, P.T.
Deposit date:2020-03-17
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:An ER translocon for multi-pass membrane protein biogenesis.
Elife, 9, 2020
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6IP5
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BU of 6ip5 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP8
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BU of 6ip8 by Molmil
Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019

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