6T7I
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![BU of 6t7i by Molmil](/molmil-images/mine/6t7i) | Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-22 | Release date: | 2019-12-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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8QOA
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![BU of 8qoa by Molmil](/molmil-images/mine/8qoa) | Structure of SecM-stalled Escherichia coli 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ... | Authors: | Gersteuer, F, Morici, M, Wilson, D.N. | Deposit date: | 2023-09-28 | Release date: | 2024-03-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome. Nat Commun, 15, 2024
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8R3V
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![BU of 8r3v by Molmil](/molmil-images/mine/8r3v) | |
8R6F
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![BU of 8r6f by Molmil](/molmil-images/mine/8r6f) | CryoEM structure of wheat 40S ribosomal subunit, body domain | Descriptor: | 30S ribosomal protein S11, chloroplastic, 30S ribosomal protein S4, ... | Authors: | Kravchenko, O.V, Baymukhametov, T.N, Afonina, Z.A, Vasilenko, K.S. | Deposit date: | 2023-11-22 | Release date: | 2023-12-27 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | High-Resolution Structure and Internal Mobility of a Plant 40S Ribosomal Subunit. Int J Mol Sci, 24, 2023
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8QPP
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![BU of 8qpp by Molmil](/molmil-images/mine/8qpp) | Bacillus subtilis MutS2-collided disome complex (stalled 70S) | Descriptor: | 16S rRNA (1533-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R. | Deposit date: | 2023-10-02 | Release date: | 2023-12-27 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. Embo J., 43, 2024
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6QZP
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![BU of 6qzp by Molmil](/molmil-images/mine/6qzp) | High-resolution cryo-EM structure of the human 80S ribosome | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA (1740-MER), 28S rRNA (3773-MER), ... | Authors: | Natchiar, S.K, Myasnikov, A.G, Kratzat, H, Hazemann, I, Klaholz, B.P. | Deposit date: | 2019-03-12 | Release date: | 2019-04-24 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Visualization of chemical modifications in the human 80S ribosome structure. Nature, 551, 2017
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6T4Q
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![BU of 6t4q by Molmil](/molmil-images/mine/6t4q) | Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-14 | Release date: | 2019-12-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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6S0X
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![BU of 6s0x by Molmil](/molmil-images/mine/6s0x) | Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | Deposit date: | 2019-06-18 | Release date: | 2019-08-21 | Method: | ELECTRON MICROSCOPY (2.425 Å) | Cite: | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Sci Rep, 9, 2019
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6RXX
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![BU of 6rxx by Molmil](/molmil-images/mine/6rxx) | Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state C, Poly-Ala | Descriptor: | 35S ribosomal RNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ... | Authors: | Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2019-06-10 | Release date: | 2019-08-14 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol.Cell, 75, 2019
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6RXV
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![BU of 6rxv by Molmil](/molmil-images/mine/6rxv) | Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state B2 | Descriptor: | 35S ribosomal RNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ... | Authors: | Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2019-06-10 | Release date: | 2019-08-14 | Last modified: | 2019-10-02 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol.Cell, 75, 2019
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6TH6
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![BU of 6th6 by Molmil](/molmil-images/mine/6th6) | Cryo-EM Structure of T. kodakarensis 70S ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M. | Deposit date: | 2019-11-18 | Release date: | 2020-07-29 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping. Nature, 583, 2020
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8QOI
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![BU of 8qoi by Molmil](/molmil-images/mine/8qoi) | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | Descriptor: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | Authors: | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | Deposit date: | 2023-09-29 | Release date: | 2024-06-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 2024
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8RDV
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![BU of 8rdv by Molmil](/molmil-images/mine/8rdv) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon, mRNA and P-site tRNA (structure 2). | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-08 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RDW
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![BU of 8rdw by Molmil](/molmil-images/mine/8rdw) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon and EF-Tu(GDP) (structure 3). | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-08 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RXH
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![BU of 8rxh by Molmil](/molmil-images/mine/8rxh) | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN | Descriptor: | (2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid, 40S ribosomal protein S12, 40S ribosomal protein S14, ... | Authors: | Rajan, K.S, Yonath, A. | Deposit date: | 2024-02-07 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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8RD8
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![BU of 8rd8 by Molmil](/molmil-images/mine/8rd8) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factors Balon and RaiA (structure 1). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S30, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-07 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RXX
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![BU of 8rxx by Molmil](/molmil-images/mine/8rxx) | |
6RXY
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![BU of 6rxy by Molmil](/molmil-images/mine/6rxy) | Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state a | Descriptor: | 35S rRNA, 40S ribosomal protein S13-like protein, 40S ribosomal protein S14-like protein, ... | Authors: | Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2019-06-10 | Release date: | 2019-08-14 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol.Cell, 75, 2019
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6TB3
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![BU of 6tb3 by Molmil](/molmil-images/mine/6tb3) | yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex | Descriptor: | 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R. | Deposit date: | 2019-10-31 | Release date: | 2020-04-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | The Ccr4-Not complex monitors the translating ribosome for codon optimality. Science, 368, 2020
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6T83
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![BU of 6t83 by Molmil](/molmil-images/mine/6t83) | Structure of yeast disome (di-ribosome) stalled on poly(A) tract. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-24 | Release date: | 2019-12-25 | Last modified: | 2020-02-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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6T7T
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![BU of 6t7t by Molmil](/molmil-images/mine/6t7t) | Structure of yeast 80S ribosome stalled on poly(A) tract. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-23 | Release date: | 2019-12-25 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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5IT9
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![BU of 5it9 by Molmil](/molmil-images/mine/5it9) | Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES. | Descriptor: | 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ... | Authors: | Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. | Deposit date: | 2016-03-16 | Release date: | 2016-05-18 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
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5JPQ
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![BU of 5jpq by Molmil](/molmil-images/mine/5jpq) | Cryo-EM structure of the 90S pre-ribosome | Descriptor: | 18S ribosomal RNA, Bms1, Emg1, ... | Authors: | Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R. | Deposit date: | 2016-05-04 | Release date: | 2016-07-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome. Cell, 166, 2016
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5JUT
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![BU of 5jut by Molmil](/molmil-images/mine/5jut) | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2016-05-10 | Release date: | 2016-10-05 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
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5KCS
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![BU of 5kcs by Molmil](/molmil-images/mine/5kcs) | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Evernimycin, mRNA, TetM and P-site tRNA at 3.9A resolution | Descriptor: | (2R,3R,4R,6S)-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7S,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-({(2R,3aS,3a'R,6S,7R,7'R,7aS,7a'S)-7'-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-7-hydroxyoctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4',7-dihydroxy-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-4-{[(2R,4S,5R,6S)-5-methoxy-4,6-dimethyl-4-nitrotetrahydro-2H-pyran-2-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N. | Deposit date: | 2016-06-06 | Release date: | 2016-08-17 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016
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