6M0W
 
 | | Crystal structure of Streptococcus thermophilus Cas9 in complex with the AGAA PAM | | 分子名称: | CRISPR-associated endonuclease Cas9 1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*GP*AP*AP*GP*C)-3'), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-23 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
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6M0X
 | | Crystal structure of Streptococcus thermophilus Cas9 in complex with AGGA PAM | | 分子名称: | BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-23 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.561 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
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6M0V
 | | Crsytal structure of streptococcus thermophilus Cas9 in complex with the GGAA PAM | | 分子名称: | BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-22 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
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8UAI
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4GKU
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6U3U
 | | Crystal Structure of Shiga Toxin 2K | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Shiga toxin 2K subunit A, ... | | 著者 | Zhang, Y.Z, He, X.H. | | 登録日 | 2019-08-22 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.287 Å) | | 主引用文献 | Structural and Functional Characterization of Stx2k, a New Subtype of Shiga Toxin 2.
Microorganisms, 8, 2019
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2MNY
 | | NMR Structure of KDM5B PHD1 finger | | 分子名称: | Lysine-specific demethylase 5B, ZINC ION | | 著者 | Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C. | | 登録日 | 2014-04-16 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B.
Protein Cell, 5, 2014
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2MNZ
 | | NMR Structure of KDM5B PHD1 finger in complex with H3K4me0(1-10aa) | | 分子名称: | H3K4me0, Lysine-specific demethylase 5B, ZINC ION | | 著者 | Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C. | | 登録日 | 2014-04-16 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B.
Protein Cell, 5, 2014
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2MK6
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6N33
 | | Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622 | | 分子名称: | 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor | | 著者 | Zhang, Y. | | 登録日 | 2018-11-14 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Nat Commun, 10, 2019
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5Z1W
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5HMC
 | | Crystal structure of S. sahachiroi AziG complexed with 5-methyl naphthoic acid | | 分子名称: | 5-methylnaphthalene-1-carboxylic acid, Azi13, SULFATE ION | | 著者 | Zhang, Y, Erb, M.S, Ealick, S.E. | | 登録日 | 2016-01-15 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.
Biochemistry, 55, 2016
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5XZD
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5XS9
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5X87
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5E18
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8KF9
 | | Stable G-quadruplex Conformation Formed in Promoter Region of Oncogene RET in 50 mM K+ solution | | 分子名称: | DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*G)-3') | | 著者 | Zhang, Y.P, Lan, W.X, Yin, S.W, Liu, Z.J, Xue, H.J, Cao, C.Y. | | 登録日 | 2023-08-15 | | 公開日 | 2024-09-04 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Stable G-quadruplex Conformation Formed in Promoter Region of Oncogene RET Indicates New Target for Anti-cancer Drug Screening
To Be Published
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8KFL
 | | Stable G-quadruplex Conformation Formed in Promoter Region of Oncogene RET in 100 mM Na+ | | 分子名称: | DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*G)-3') | | 著者 | Zhang, Y.P, Lan, W.X, Yin, S.W, Liu, Z.J, Xue, H.J, Cao, C.Y. | | 登録日 | 2023-08-15 | | 公開日 | 2024-09-04 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Stable G-quadruplex Conformation Formed in Promoter Region of Oncogene RET Indicates New Target for Anti-cancer Drug Screening
To Be Published
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8CZJ
 | | A bacteria Zrt/Irt-like protein in the apo state | | 分子名称: | Putative membrane protein, SULFATE ION, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | | 著者 | Zhang, Y, Hu, J. | | 登録日 | 2022-05-24 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | | 主引用文献 | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter.
Nat Commun, 14, 2023
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8AEY
 | | 3 A CRYO-EM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FERRITIN FROM TIMEPIX3 detector | | 分子名称: | Ferritin BfrB | | 著者 | Zhang, Y, van Schayck, J.P, Knoops, K, Peters, P.J, Ravelli, R.B.G. | | 登録日 | 2022-07-14 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Integration of an Event-driven Timepix3 Hybrid Pixel Detector into a Cryo-EM Workflow
Microsc Microanal, 2023
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6A9D
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6A37
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8E4V
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5X21
 | | Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) | | 分子名称: | (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Zhang, Y, Ebright, R. | | 登録日 | 2017-01-29 | | 公開日 | 2017-07-05 | | 最終更新日 | 2022-10-12 | | 実験手法 | X-RAY DIFFRACTION (3.323 Å) | | 主引用文献 | Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell, 169, 2017
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5X22
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