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8KFL

Stable G-quadruplex Conformation Formed in Promoter Region of Oncogene RET in 100 mM Na+

Summary for 8KFL
Entry DOI10.2210/pdb8kfl/pdb
DescriptorDNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*G)-3') (1 entity in total)
Functional Keywordsret oncogene, g-quadruplex, drug screening, dna
Biological sourcesynthetic construct
Total number of polymer chains1
Total formula weight6707.28
Authors
Zhang, Y.P.,Lan, W.X.,Yin, S.W.,Liu, Z.J.,Xue, H.J.,Cao, C.Y. (deposition date: 2023-08-15, release date: 2024-09-04)
Primary citationZhang, Y.P.,Lan, W.X.,Yin, S.W.,Liu, Z.J.,Xue, H.J.,Cao, C.Y.
Stable G-quadruplex Conformation Formed in Promoter Region of Oncogene RET Indicates New Target for Anti-cancer Drug Screening
To Be Published,
Experimental method
SOLUTION NMR
Structure validation

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PDB entries from 2024-11-06

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