5X87

Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation L177T

Summary for 5X87

• Entry DOI: 10.2210/pdb5x87/pdb
• Descriptor: Bestrophin, ZINC ION (3 entities in total)
• Functional Keywords: bestrophin, klebsiella pneumoniae, mutation, membrane protein
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 5
• Total formula weight: 170077.08

Authors

Zhang, Y.,Chen, S.,Yang, T. (deposition date: 2017-03-01, release date: 2017-11-01, Last modification date: 2023-11-29)

• Primary citation: Li, Y.,Zhang, Y.,Xu, Y.,Kittredge, A.,Ward, N.,Chen, S.,Tsang, S.H.,Yang, T.; Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca2+-dependent Cl-currents in human RPE.; Elife, 6:-, 2017; PubMed: 29063836; DOI: 10.7554/eLife.29914

Experimental method

X-RAY DIFFRACTION (3.14 Å)