6M0X

Crystal structure of Streptococcus thermophilus Cas9 in complex with AGGA PAM

Summary for 6M0X

• Entry DOI: 10.2210/pdb6m0x/pdb
• Descriptor: CRISPR-associated endonuclease Cas9 1, RNA (71-MER), DNA (28-MER), ... (7 entities in total)
• Functional Keywords: cas9, crispr, dna binding protein
• Biological source: Streptococcus thermophilus LMD-9; More
• Total number of polymer chains: 4
• Total formula weight: 165466.86

Authors

Zhang, Y.,Zhang, H.,Xu, X.,Wang, Y.,Chen, W.,Wang, Y.,Wu, Z.,Tang, N.,Wang, Y.,Zhao, S.,Gan, J.,Ji, Q. (deposition date: 2020-02-23, release date: 2020-09-09, Last modification date: 2023-11-29)

• Primary citation: Zhang, Y.,Zhang, H.,Xu, X.,Wang, Y.,Chen, W.,Wang, Y.,Wu, Z.,Tang, N.,Wang, Y.,Zhao, S.,Gan, J.,Ji, Q.; Catalytic-state structure and engineering of Streptococcus thermophilus Cas9; Nat Catal, 2020; DOI: 10.1038/s41929-020-00506-9

Experimental method

X-RAY DIFFRACTION (2.561 Å)