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5HMC

Crystal structure of S. sahachiroi AziG complexed with 5-methyl naphthoic acid

Summary for 5HMC
Entry DOI10.2210/pdb5hmc/pdb
Related5HMB
DescriptorAzi13, 5-methylnaphthalene-1-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywordsazinomycin biosynthesis, polyketide synthase, thioesterase, naphthoate, hydrolase
Biological sourceStreptomyces sahachiroi
Total number of polymer chains1
Total formula weight15794.55
Authors
Zhang, Y.,Erb, M.S.,Ealick, S.E. (deposition date: 2016-01-15, release date: 2016-02-03, Last modification date: 2024-04-03)
Primary citationMori, S.,Simkhada, D.,Zhang, H.,Erb, M.S.,Zhang, Y.,Williams, H.,Fedoseyenko, D.,Russell, W.K.,Kim, D.,Fleer, N.,Ealick, S.E.,Watanabe, C.M.
Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.
Biochemistry, 55:704-714, 2016
Cited by
PubMed: 26731610
DOI: 10.1021/acs.biochem.5b01050
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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