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PDB: 143 results

7RXE
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Crystal structure of junctophilin-2
Descriptor: CITRATE ANION, ISOPROPYL ALCOHOL, Junctophilin-2 N-terminal fragment
Authors:Yang, Z, Panwar, P, Van Petegem, F.
Deposit date:2021-08-22
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RW4
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BU of 7rw4 by Molmil
Crystal structure of junctophilin-1
Descriptor: ACETATE ION, GLYCEROL, Junctophilin-1
Authors:Yang, Z, Panwar, P, Van Petegem, F.
Deposit date:2021-08-19
Release date:2022-02-23
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RXQ
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Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide
Descriptor: ETHANOL, Junctophilin-2 N-terminal fragment, SULFATE ION, ...
Authors:Yang, Z, Panwar, P, Van Petegem, F.
Deposit date:2021-08-23
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
2XOA
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BU of 2xoa by Molmil
Crystal Structure of the N-terminal three domains of the skeletal muscle Ryanodine Receptor (RyR1)
Descriptor: RYANODINE RECEPTOR 1
Authors:Tung, C, Lobo, P.A, Kimlicka, L, Van Petegem, F.
Deposit date:2010-08-10
Release date:2010-11-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Amino-Terminal Disease Hotspot of Ryanodine Receptors Forms a Cytoplasmic Vestibule.
Nature, 468, 2010
1PG5
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BU of 1pg5 by Molmil
CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS
Descriptor: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J.
Deposit date:2003-05-27
Release date:2004-06-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
6Y4P
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BU of 6y4p by Molmil
Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
Descriptor: CALCIUM ION, Calmodulin-1, Ryanodine receptor 2
Authors:Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
Deposit date:2020-02-21
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.13325572 Å)
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6Y4O
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BU of 6y4o by Molmil
Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
Descriptor: CALCIUM ION, Calmodulin-2, Ryanodine receptor 2
Authors:Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
Deposit date:2020-02-21
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83549082 Å)
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6B28
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Crystal structure of human STAC2 Tandem SH3 Domains Q347I (296-411)
Descriptor: SH3 and cysteine-rich domain-containing protein 2
Authors:Wong King Yuen, S.M, Tung, C.C, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B26
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Crystal structure of human STAC2 Tandem SH3 Domains (296-411)
Descriptor: SH3 and cysteine-rich domain-containing protein 2
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B25
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BU of 6b25 by Molmil
Crystal structure of human STAC1 Tandem SH3 Domains (288-402)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6X36
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BU of 6x36 by Molmil
Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6X32
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BU of 6x32 by Molmil
Wt pig RyR1 in complex with apoCaM, EGTA condition (class 1 and 2, closed)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6X35
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BU of 6x35 by Molmil
Pig R615C RyR1 in complex with CaM, EGTA (class 1, open)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6X33
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BU of 6x33 by Molmil
Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6X34
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BU of 6x34 by Molmil
Pig R615C RyR1 EGTA (all classes, open)
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ZINC ION
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-05-21
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
5C30
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BU of 5c30 by Molmil
Crystal Structure of Rabbit Ryanodine Receptor 1 Repeat12 Domain
Descriptor: ISOPROPYL ALCOHOL, Ryanodine receptor 1
Authors:Yuchi, Z, Van Petegem, F.
Deposit date:2015-06-16
Release date:2015-08-05
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
5C33
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BU of 5c33 by Molmil
Crystal Structure of Mouse Ryanodine Receptor 2 SPRY1 Domain
Descriptor: CHLORIDE ION, ISOPROPYL ALCOHOL, Ryanodine receptor 2
Authors:Yuchi, Z, Van Petegem, F.
Deposit date:2015-06-16
Release date:2015-08-05
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
5DZG
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BU of 5dzg by Molmil
Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with a xyloglucan tetradecasaccharide
Descriptor: VvEG16, endo-glucanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
Deposit date:2015-09-25
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
5DZE
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BU of 5dze by Molmil
Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with cellotetraose
Descriptor: beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, endo-glucanase
Authors:McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
Deposit date:2015-09-25
Release date:2016-09-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
1H71
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BU of 1h71 by Molmil
Psychrophilic Protease from Pseudoalteromonas 'TAC II 18'
Descriptor: CALCIUM ION, SERRALYSIN, ZINC ION
Authors:Villeret, V, Van Petegem, F, Aghajari, N, Chessa, J.-P, Gerday, C, Haser, R, Van Beeumen, J.
Deposit date:2001-07-02
Release date:2003-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003
6PYA
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BU of 6pya by Molmil
Sex Hormone-binding globulin mutant E176K in complex with IPI
Descriptor: 3-[(1H-imidazol-1-yl)methyl]-2-phenyl-1H-indole, CALCIUM ION, Sex hormone-binding globulin
Authors:Round, P.W, Das, S, Van Petegem, F.
Deposit date:2019-07-29
Release date:2019-12-25
Last modified:2020-02-12
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
6PYF
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BU of 6pyf by Molmil
Sex Hormone-binding globulin mutant E176K in complex with Estradiol
Descriptor: CALCIUM ION, ESTRADIOL, Sex hormone-binding globulin
Authors:Round, P.W, Wu, T.S, Das, S, Van Petegem, F.
Deposit date:2019-07-29
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
5KHG
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BU of 5khg by Molmil
HCN2 CNBD in complex with cytidine-3', 5'-cyclic monophosphate (cCMP)
Descriptor: 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
Deposit date:2016-06-14
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
6PYB
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BU of 6pyb by Molmil
Sex Hormone-binding globulin mutant E176K in complex with DVT
Descriptor: 4,4'-[(3R,4R)-oxolane-3,4-diylbis(methylene)]bis(2-methoxyphenol), CALCIUM ION, Sex hormone-binding globulin
Authors:Round, P.W, Das, S, Van Petegem, F.
Deposit date:2019-07-29
Release date:2019-12-25
Last modified:2020-02-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
5KHJ
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BU of 5khj by Molmil
HCN2 CNBD in complex with uridine-3', 5'-cyclic monophosphate (cUMP)
Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, Uridine-3',5'-cyclic monophosphate
Authors:Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
Deposit date:2016-06-14
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016

221716

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