7RXQ
Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide
Summary for 7RXQ
| Entry DOI | 10.2210/pdb7rxq/pdb |
| Related | 7RW4 7RXE |
| Descriptor | Junctophilin-2 N-terminal fragment, Voltage-dependent L-type calcium channel subunit alpha-1S, ETHANOL, ... (5 entities in total) |
| Functional Keywords | complex, membrane, ion channel, structural protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 38340.06 |
| Authors | Yang, Z.,Panwar, P.,Van Petegem, F. (deposition date: 2021-08-23, release date: 2022-02-23, Last modification date: 2023-10-18) |
| Primary citation | Yang, Z.F.,Panwar, P.,McFarlane, C.R.,Tuinte, W.E.,Campiglio, M.,Van Petegem, F. Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations. Proc.Natl.Acad.Sci.USA, 119:e2120416119-e2120416119, 2022 Cited by PubMed: 35238659DOI: 10.1073/pnas.2120416119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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