7RXQ
Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Junctophilin-2 N-terminal fragment | polymer | 327 | 36122.7 | 1 | UniProt (Q9BR39) Pfam (PF02493) In PDB | Homo sapiens (Human) | JP2NT |
| 2 | B | Voltage-dependent L-type calcium channel subunit alpha-1S | polymer | 16 | 1883.1 | 1 | UniProt (P07293) In PDB | Oryctolagus cuniculus | Calcium channel,L type,alpha-1 polypeptide,isoform 3,skeletal muscle,Dihydropyridine receptor alpha-1S subunit,DHPR,Voltage-gated calcium channel subunit alpha Cav1.1 |
| 3 | A | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A: 1 - 437 (UniProt: Q9BR39)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| - | Ser 162 | deletion |
| - | Leu 163 | deletion |
| - | Ser 164 | deletion |
| - | Ser 165 | deletion |
| - | Leu 166 | deletion |
| - | Arg 167 | deletion |
| - | Ser 168 | deletion |
| - | Glu 169 | deletion |
| - | His 170 | deletion |
| - | Ser 171 | deletion |
| - | Asn 172 | deletion |
| - | Gly 173 | deletion |
| - | Thr 174 | deletion |
| - | Val 175 | deletion |
| - | Ala 176 | deletion |
| - | Pro 177 | deletion |
| - | Asp 178 | deletion |
| - | Ser 179 | deletion |
| - | Pro 180 | deletion |
| - | Ala 181 | deletion |
| - | Ser 182 | deletion |
| - | Pro 183 | deletion |
| - | Ala 184 | deletion |
| - | Ser 185 | deletion |
| - | Asp 186 | deletion |
| - | Gly 187 | deletion |
| - | Pro 188 | deletion |
| - | Ala 189 | deletion |
| - | Leu 190 | deletion |
| - | Pro 191 | deletion |
| - | Ser 192 | deletion |
| - | Pro 193 | deletion |
| - | Ala 194 | deletion |
| - | Ile 195 | deletion |
| - | Pro 196 | deletion |
| - | Arg 197 | deletion |
| - | Gly 198 | deletion |
| - | Gly 199 | deletion |
| - | Phe 200 | deletion |
| - | Ala 201 | deletion |
| - | Leu 202 | deletion |
| - | Ser 203 | deletion |
| - | Leu 204 | deletion |
| - | Leu 205 | deletion |
| - | Ala 206 | deletion |
| - | Asn 207 | deletion |
| - | Ala 208 | deletion |
| - | Glu 209 | deletion |
| - | Ala 210 | deletion |
| - | Ala 211 | deletion |
| - | Ala 212 | deletion |
| - | Arg 213 | deletion |
| - | Ala 214 | deletion |
| - | Pro 215 | deletion |
| - | Lys 216 | deletion |
| - | Gly 217 | deletion |
| - | Gly 218 | deletion |
| - | Gly 219 | deletion |
| - | Leu 220 | deletion |
| - | Phe 221 | deletion |
| - | Gln 222 | deletion |
| - | Arg 223 | deletion |
| - | Gly 224 | deletion |
| - | Ala 225 | deletion |
| - | Leu 226 | deletion |
| - | Leu 227 | deletion |
| - | Gly 228 | deletion |
| - | Lys 229 | deletion |
| - | Leu 230 | deletion |
| - | Arg 231 | deletion |
| - | Arg 232 | deletion |
| - | Ala 233 | deletion |
| - | Glu 234 | deletion |
| - | Ser 235 | deletion |
| - | Arg 236 | deletion |
| - | Thr 237 | deletion |
| - | Ser 238 | deletion |
| - | Val 239 | deletion |
| - | Gly 240 | deletion |
| - | Ser 241 | deletion |
| - | Gln 242 | deletion |
| - | Arg 243 | deletion |
| - | Ser 244 | deletion |
| - | Arg 245 | deletion |
| - | Val 246 | deletion |
| - | Ser 247 | deletion |
| - | Phe 248 | deletion |
| - | Leu 249 | deletion |
| - | Lys 250 | deletion |
| - | Ser 251 | deletion |
| - | Asp 252 | deletion |
| - | Leu 253 | deletion |
| - | Ser 254 | deletion |
| - | Ser 255 | deletion |
| - | Gly 256 | deletion |
| - | Ala 257 | deletion |
| - | Ser 258 | deletion |
| - | Asp 259 | deletion |
| - | Ala 260 | deletion |
| - | Ala 261 | deletion |
| - | Ser 262 | deletion |
| - | Thr 263 | deletion |
| - | Ala 264 | deletion |
| - | Ser 265 | deletion |
| - | Leu 266 | deletion |
| - | Gly 267 | deletion |
| - | Glu 268 | deletion |
| - | Ala 269 | deletion |
| - | Ala 270 | deletion |
| - | Glu 271 | deletion |
| - | Gly 272 | deletion |
| - | Ala 273 | deletion |
| - | Asp 274 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38005.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 334.3 | |
| All* | Total formula weight | 38340.1 |
