8SF0
 
 | | Cryo-EM Structure of RyR1 + cAMP (Local Refinement of TMD) | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION | | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | | 登録日 | 2023-04-10 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
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8SEZ
 | | Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD) | | 分子名称: | ADENINE, Ryanodine receptor 1, ZINC ION | | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | | 登録日 | 2023-04-10 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
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8SEX
 | | Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD) | | 分子名称: | ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION | | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | | 登録日 | 2023-04-10 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
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6PAL
 | | Bacteroides uniformis endo-laminarinase BuGH158 from the beta(1,3)-glucan utilization locus | | 分子名称: | ACETATE ION, SULFATE ION, Uncharacterized protein | | 著者 | Tamura, K, Brumer, H, van Petegem, F. | | 登録日 | 2019-06-11 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.818 Å) | | 主引用文献 | Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human GutBacteroides.
Mbio, 11, 2020
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6M2W
 | | Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL) | | 分子名称: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... | | 著者 | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | | 登録日 | 2020-03-01 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
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5DZG
 | | Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with a xyloglucan tetradecasaccharide | | 分子名称: | VvEG16, endo-glucanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H. | | 登録日 | 2015-09-25 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
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5FDY
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6MUD
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5FEB
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6MUE
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6PYA
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6PYF
 | | Sex Hormone-binding globulin mutant E176K in complex with Estradiol | | 分子名称: | CALCIUM ION, ESTRADIOL, Sex hormone-binding globulin | | 著者 | Round, P.W, Wu, T.S, Das, S, Van Petegem, F. | | 登録日 | 2019-07-29 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
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6PYB
 | | Sex Hormone-binding globulin mutant E176K in complex with DVT | | 分子名称: | 4,4'-[(3R,4R)-oxolane-3,4-diylbis(methylene)]bis(2-methoxyphenol), CALCIUM ION, Sex hormone-binding globulin | | 著者 | Round, P.W, Das, S, Van Petegem, F. | | 登録日 | 2019-07-29 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-02-12 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
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5DZE
 | | Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with cellotetraose | | 分子名称: | beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, endo-glucanase | | 著者 | McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H. | | 登録日 | 2015-09-25 | | 公開日 | 2016-09-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
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5DZF
 | | Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with a mixed-linkage glucan octasaccharide | | 分子名称: | SULFATE ION, beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H. | | 登録日 | 2015-09-25 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
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6Y4O
 | | Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | | 分子名称: | CALCIUM ION, Calmodulin-2, Ryanodine receptor 2 | | 著者 | Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R. | | 登録日 | 2020-02-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.83549082 Å) | | 主引用文献 | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y4P
 | | Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | | 分子名称: | CALCIUM ION, Calmodulin-1, Ryanodine receptor 2 | | 著者 | Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R. | | 登録日 | 2020-02-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.13325572 Å) | | 主引用文献 | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6B29
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6X35
 | | Pig R615C RyR1 in complex with CaM, EGTA (class 1, open) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6X33
 | | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6B27
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1VYD
 | | Crystal structure of cytochrome C2 mutant G95E | | 分子名称: | CYTOCHROME C2, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Dumortier, C, Fitch, J, Van Petegem, F, Vermeulen, W, Meyer, T.E, Van Beeumen, J.J, Cusanovich, M.A. | | 登録日 | 2004-04-27 | | 公開日 | 2004-06-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Protein Dynamics in the Region of the Sixth Ligand Methionine Revealed by Studies of Imidazole Binding to Rhodobacter Capsulatus Cytochrome C2 Hinge Mutants.
Biochemistry, 43, 2004
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6VSV
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6X36
 | | Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6X32
 | | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 1 and 2, closed) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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