6B27
Crystal structure of human STAC2 Tandem SH3 Domains (296-411) in complex with a CaV1.1 II-III loop peptide
Summary for 6B27
Entry DOI | 10.2210/pdb6b27/pdb |
Descriptor | SH3 and cysteine-rich domain-containing protein 2, Voltage-dependent L-type calcium channel subunit alpha-1S, SULFATE ION, ... (5 entities in total) |
Functional Keywords | excitation-contraction coupling, ion channel adaptor protein, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 91469.31 |
Authors | Wong King Yuen, S.M.,Van Petegem, F. (deposition date: 2017-09-19, release date: 2017-10-25, Last modification date: 2024-03-13) |
Primary citation | Wong King Yuen, S.M.,Campiglio, M.,Tung, C.C.,Flucher, B.E.,Van Petegem, F. Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114:E9520-E9528, 2017 Cited by PubMed: 29078335DOI: 10.1073/pnas.1708852114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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