4ZUW
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![BU of 4zuw by Molmil](/molmil-images/mine/4zuw) | Crystal structure of Equine MHC I(Eqca-N*00601) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-GW12 | Descriptor: | Beta-2-microglobulin, Classical MHC class I antigen, GLY-SER-GLN-LYS-LEU-THR-THR-GLY-ASN-CYS-ASN-TRP | Authors: | Yao, S, Liu, J, Qi, J, Chen, R, Zhang, N, Liu, Y, Xia, C. | Deposit date: | 2015-05-17 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles J Immunol., 196, 2016
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6N8Z
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![BU of 6n8z by Molmil](/molmil-images/mine/6n8z) | HSP104DWB extended conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104 | Authors: | Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F. | Deposit date: | 2018-11-30 | Release date: | 2019-01-02 | Last modified: | 2019-01-16 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Rep, 26, 2019
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5K0K
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![BU of 5k0k by Molmil](/molmil-images/mine/5k0k) | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2434 | Descriptor: | 15-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}-4,5,6,7,9,10,11,12-octahydro-2,16-(azenometheno)pyrrolo[2,1-d][1,3,5,9]te traazacyclotetradecin-8(3H)-one, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Wang, X, Liu, J, Zhang, W, Stashko, M.A, Nichols, J, DeRyckere, D, Miley, M.J, Norris-Drouin, J, Chen, Z, Machius, M, Wood, E, Graham, D.K, Earp, H.S, Graham, K, Kireev, D, Frye, S.V. | Deposit date: | 2016-05-17 | Release date: | 2017-01-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors. ACS Med Chem Lett, 7, 2016
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1MIT
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![BU of 1mit by Molmil](/molmil-images/mine/1mit) | RECOMBINANT CUCURBITA MAXIMA TRYPSIN INHIBITOR V (RCMTI-V) (NMR, MINIMIZED AVERAGE STRUCTURE) | Descriptor: | TRYPSIN INHIBITOR V | Authors: | Cai, M, Gong, Y, Huang, Y, Liu, J, Prakash, O, Wen, L, Wen, J.J, Huang, J.-K, Krishnamoorthi, R. | Deposit date: | 1995-10-26 | Release date: | 1996-04-03 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of recombinant Cucurbita maxima trypsin inhibitor-V determined by NMR spectroscopy. Biochemistry, 35, 1996
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7NHS
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![BU of 7nhs by Molmil](/molmil-images/mine/7nhs) | Wzc K540M C8 | Descriptor: | Putative transmembrane protein Wzc | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-11 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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7NI2
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![BU of 7ni2 by Molmil](/molmil-images/mine/7ni2) | Wzc-K540M-4YE C8 | Descriptor: | Tyrosine-protein kinase | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-11 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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7NIB
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![BU of 7nib by Molmil](/molmil-images/mine/7nib) | Wzc-K540M-4YE C1 | Descriptor: | Tyrosine-protein kinase | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-11 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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6OCP
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![BU of 6ocp by Molmil](/molmil-images/mine/6ocp) | Crystal structure of a human GABAB receptor peptide bound to KCTD16 T1 | Descriptor: | BTB/POZ domain-containing protein KCTD16, Gamma-aminobutyric acid type B receptor subunit 2 | Authors: | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | Deposit date: | 2019-03-25 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor. Proc.Natl.Acad.Sci.USA, 116, 2019
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6OCR
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![BU of 6ocr by Molmil](/molmil-images/mine/6ocr) | Crystal structure of human KCTD16 T1 domain | Descriptor: | BTB/POZ domain-containing protein KCTD16 | Authors: | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | Deposit date: | 2019-03-25 | Release date: | 2019-04-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor. Proc.Natl.Acad.Sci.USA, 116, 2019
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1LB2
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![BU of 1lb2 by Molmil](/molmil-images/mine/1lb2) | Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA | Descriptor: | 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*AP*G)-3', 5'-D(*CP*TP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | Authors: | Benoff, B, Yang, H, Lawson, C.L, Parkinson, G, Liu, J, Blatter, E, Ebright, Y.W, Berman, H.M, Ebright, R.H. | Deposit date: | 2002-04-01 | Release date: | 2002-09-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of transcription activation: the CAP-alpha CTD-DNA complex. Science, 297, 2002
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6N8T
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![BU of 6n8t by Molmil](/molmil-images/mine/6n8t) | Hsp104DWB closed conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104 | Authors: | Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F. | Deposit date: | 2018-11-30 | Release date: | 2019-01-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Rep, 26, 2019
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6OCT
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![BU of 6oct by Molmil](/molmil-images/mine/6oct) | Crystal structure of human KCTD16 T1 domain | Descriptor: | BTB/POZ domain-containing protein KCTD16 | Authors: | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | Deposit date: | 2019-03-25 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor. Proc.Natl.Acad.Sci.USA, 116, 2019
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7LH9
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![BU of 7lh9 by Molmil](/molmil-images/mine/7lh9) | Crystal structure of BRPF2 PWWP domain in complex with DNA | Descriptor: | Bromodomain-containing protein 1, DNA | Authors: | Zhang, M, Lei, M, Qin, S, Dong, A, Yang, A, Li, Y, Loppnau, P, Hughes, T.R, Arrowsmith, C.H, Edwards, A.M, Min, J, Liu, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-01-21 | Release date: | 2021-02-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains. Biochim Biophys Acta Gene Regul Mech, 1864, 2021
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5GRJ
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![BU of 5grj by Molmil](/molmil-images/mine/5grj) | Crystal structure of human PD-L1 with monoclonal antibody avelumab | Descriptor: | Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain | Authors: | Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. | Deposit date: | 2016-08-11 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.206 Å) | Cite: | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell Res., 27, 2017
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1IG3
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![BU of 1ig3 by Molmil](/molmil-images/mine/1ig3) | Mouse Thiamin Pyrophosphokinase Complexed with Thiamin | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, SULFATE ION, thiamin pyrophosphokinase | Authors: | Timm, D.E, Liu, J, Baker, L.-J, Harris, R.A. | Deposit date: | 2001-04-16 | Release date: | 2001-04-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of thiamin pyrophosphokinase. J.Mol.Biol., 310, 2001
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3QIC
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![BU of 3qic by Molmil](/molmil-images/mine/3qic) | The structure of human glucokinase E339K mutation | Descriptor: | GLYCEROL, Glucokinase, alpha-D-glucopyranose | Authors: | Liu, Q, Liu, S, Liu, J. | Deposit date: | 2011-01-27 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site. Febs Lett., 585, 2011
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3TI4
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![BU of 3ti4 by Molmil](/molmil-images/mine/3ti4) | Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with laninamivir octanoate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-9-O-octanoyl-D-glycero-D-galacto-non-2-enonic acid, ACETATE ION, ... | Authors: | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | Deposit date: | 2011-08-20 | Release date: | 2011-11-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
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3TIC
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![BU of 3tic by Molmil](/molmil-images/mine/3tic) | Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with zanamivir | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | Deposit date: | 2011-08-20 | Release date: | 2011-11-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
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6WN3
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![BU of 6wn3 by Molmil](/molmil-images/mine/6wn3) | |
6WNB
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![BU of 6wnb by Molmil](/molmil-images/mine/6wnb) | |
3TIA
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![BU of 3tia by Molmil](/molmil-images/mine/3tia) | Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, ... | Authors: | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | Deposit date: | 2011-08-20 | Release date: | 2011-11-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
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6WNC
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![BU of 6wnc by Molmil](/molmil-images/mine/6wnc) | |
6WND
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![BU of 6wnd by Molmil](/molmil-images/mine/6wnd) | |
1MJN
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![BU of 1mjn by Molmil](/molmil-images/mine/1mjn) | Crystal Structure of the intermediate affinity aL I domain mutant | Descriptor: | Integrin alpha-L, MAGNESIUM ION | Authors: | Shimaoka, M, Xiao, T, Liu, J.H, Yang, Y.T, Dong, Y.C, Jun, C.D, McCormack, A, Zhang, R.G, Wang, J.H, Springer, T.A. | Deposit date: | 2002-08-28 | Release date: | 2003-01-28 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of the alphaL I Domain and its Complex with ICAM-1 reveal a Shape-shifting Pathway for Integrin Regulation Cell(Cambridge,Mass.), 112, 2003
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1HUZ
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![BU of 1huz by Molmil](/molmil-images/mine/1huz) | CRYSTAL STRUCTURE OF DNA POLYMERASE COMPLEXED WITH DNA AND CR-PCP | Descriptor: | 5'-D(*AP*AP*TP*AP*GP*GP*CP*GP*TP*CP*G)-3', 5'-D(P*CP*GP*AP*CP*GP*CP*CP*T)-3', CHROMIUM ION, ... | Authors: | Arndt, J.W, Gong, W, Zhong, X, Showalter, A.K, Liu, J, Lin, Z, Paxson, C, Tsai, M.-D, Chan, M.K. | Deposit date: | 2001-01-04 | Release date: | 2001-04-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. Biochemistry, 40, 2001
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