Crystal structure of high affinity alphaL I domain in the absence of ligand or metal

Summary for 1MQA

Related1MQ8 1MQ9
DescriptorIntegrin alpha-L (2 entities in total)
Functional Keywordsdesigned disulfide bridge, rossmann fold, immune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P20701
Total number of polymer chains1
Total molecular weight20495.5
Shimaoka, T.,Xiao, T.,Liu, J.-H.,Yang, Y.,Dong, Y.,Jun, C.-D.,Zhang, R.,Takagi, J.,Wang, J.-H.,Springer, T.A. (deposition date: 2002-09-15, release date: 2003-01-14, Last modification date: 2011-07-13)
Primary citation
Shimaoka, M.,Xiao, T.,Liu, J.-H.,Yang, Y.,Dong, Y.,Jun, C.-D.,McCormack, A.,Zhang, R.,Joachimiak, A.,Takagi, J.,Wang, J.-H.,Springer, T.A.
Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Cell(Cambridge,Mass.), 112:99-111, 2003
PubMed: 12526797 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(02)01257-6
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers131.2%8.4%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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