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PDB: 1640 件

7D09
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Acinetobacter MlaFEDB complex in ATP-bound Vtrans2 conformation
分子名称: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
著者Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
登録日2020-09-09
公開日2020-12-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D08
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Acinetobacter MlaFEDB complex in ATP-bound Vtrans1 conformation
分子名称: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
著者Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
登録日2020-09-09
公開日2020-12-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7C8G
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Structure of alginate lyase AlyC3
分子名称: Alginate lyase AlyC3, GLYCEROL, SUCCINIC ACID
著者Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P.
登録日2020-05-30
公開日2020-10-07
最終更新日2020-12-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic.
J.Biol.Chem., 295, 2020
7C8F
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Structure of alginate lyase AlyC3 in complex with dimannuronate(2M)
分子名称: H127A/Y244A mutant of alginate lyase AlyC3 in complex with dimannuronate, MALONATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid
著者Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P.
登録日2020-05-30
公開日2020-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.461 Å)
主引用文献Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic.
J.Biol.Chem., 295, 2020
7WF9
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Crystal structure of mouse SNX25 RGS domain in space group P41212
分子名称: Sorting nexin-25
著者Zhang, Y, Xu, J, Liu, J.
登録日2021-12-26
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins.
J.Mol.Biol., 434, 2022
7WF8
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Crystal structure of mouse SNX25 RGS domain in space group P212121
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Zhang, Y, Xu, J, Liu, J.
登録日2021-12-26
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins.
J.Mol.Biol., 434, 2022
7DK8
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Crystal structure of OsGH3-8 with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Probable indole-3-acetic acid-amido synthetase GH3.8
著者Zhang, Y.K, Xu, G.L, Ming, Z.H.
登録日2020-11-23
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of the acyl acid amido synthetase GH3-8 from Oryza sativa.
Biochem.Biophys.Res.Commun., 534, 2021
7XH3
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Dimeric G-quadruplex DNA Formed in the Proximal Promoter of VEGFR-2
分子名称: DNA (5'-D(*CP*CP*GP*GP*GP*TP*AP*CP*CP*CP*GP*G)-3')
著者Zhang, Y, Lan, W, Wang, C, Cao, C.
登録日2022-04-07
公開日2023-02-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric G-quadruplex DNA Structure in the Proximal Promoter of VEGFR-2 Reveals a New Drug Target to Inhibit Tumor Angiogenesis.
Chin.J.Chem., 40, 2022
7XFV
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Dimeric G-quadruplex DNA Formed in the Proximal Promoter of VEGFR-2
分子名称: DNA (5'-D(*AP*TP*GP*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')
著者Zhang, Y, Lan, W, Wang, C, Cao, C.
登録日2022-04-02
公開日2023-03-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric G-quadruplex DNA Structure in the Proximal Promoter of VEGFR-2 Reveals a New Drug Target to Inhibit Tumor Angiogenesis.
Chin.J.Chem., 40, 2023
7E7S
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BU of 7e7s by Molmil
WT transporter state1
分子名称: CALCIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
著者Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K.
登録日2021-02-27
公開日2021-09-08
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca 2+ -ATPase SERCA2b.
Embo J., 40, 2021
7D6E
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Structural insights into membrane remodeling by SNX1
分子名称: Sorting nexin-1
著者Zhang, Y, Pang, X, Sun, F.
登録日2020-09-30
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural insights into membrane remodeling by SNX1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7D6D
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Structural insights into membrane remodeling by SNX1
分子名称: Sorting nexin-1
著者Zhang, Y, Pang, X, Sun, F.
登録日2020-09-30
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural insights into membrane remodeling by SNX1.
Proc.Natl.Acad.Sci.USA, 118, 2021
6PWW
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Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
4URT
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The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R.
登録日2014-07-02
公開日2014-09-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue
Neuron, 83, 2014
4R5Y
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The complex structure of Braf V600E kinase domain with a novel Braf inhibitor
分子名称: 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf
著者Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M.
登録日2014-08-22
公開日2016-02-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Mol.Cancer Ther., 14, 2015
7C1L
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Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant R148A in complex with C8-CoA
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A
著者Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X.
登録日2020-05-05
公開日2020-11-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis.
Nat Commun, 12, 2021
7C1U
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Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140V/R148A in a "product-released" conformation
分子名称: Non-ribosomal peptide synthetase modules
著者Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X.
登録日2020-05-05
公開日2020-11-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis.
Nat Commun, 12, 2021
4I48
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BU of 4i48 by Molmil
Structure of HLA-A68 complexed with an HIV Env derived peptide
分子名称: 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F.
登録日2012-11-27
公開日2013-10-02
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
7S3V
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Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity towards kynurenine
分子名称: Kynureninase
著者Burkholder, N.T, Zhang, Y.J.
登録日2021-09-08
公開日2022-12-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.249 Å)
主引用文献Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.
Nat Catal, 5, 2022
6VUA
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X-ray structure of human CD38 catalytic domain with 2'-Cl-araNAD+
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, DI(HYDROXYETHYL)ETHER, ...
著者Dai, Z, Zhang, X.N, Nasertorabi, F, Han, G.W, Stevens, R.C, Zhang, Y.
登録日2020-02-14
公開日2020-06-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases.
Sci Adv, 6, 2020
6J76
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Structure of 3,6-anhydro-L-galactose Dehydrogenase in Complex with NAP
分子名称: Aldehyde dehydrogenase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.368 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
5V1X
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Carbon Sulfoxide lyase, Egt2 Y134F in complex with its substrate
分子名称: (1S)-2-{2-[(R)-(2R)-2-amino-2-carboxyethanesulfinyl]-1H-imidazol-4-yl}-1-carboxy-N,N,N-trimethylethan-1-aminium, FORMIC ACID, Hercynylcysteine sulfoxide lyase
著者Irani, S, Zhang, Y.
登録日2017-03-02
公開日2018-03-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.558 Å)
主引用文献Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.
Cell Chem Biol, 25, 2018
6IK4
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A Novel M23 Metalloprotease Pseudoalterin from Deep-sea
分子名称: Elastinolytic metalloprotease, GLYCEROL, ZINC ION
著者Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z.
登録日2018-10-14
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020
5UTS
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Carbon Sulfoxide lyase, Egt2 in the Ergothioneine biosynthesis pathway
分子名称: C-S Lyase Egt2, FORMIC ACID
著者Irani, S, Zhang, Y.
登録日2017-02-15
公開日2018-02-21
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.
Cell Chem Biol, 25, 2018
6IJC
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Structure of MMPA-CoA dehydrogenase from Roseovarius nubinhibens ISM
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acyl-CoA dehydrogenase family protein
著者Shao, X, Yuan, Z.L, Cao, H.Y, Wang, P, Li, C.Y, Chen, X.L, Zhang, Y.Z.
登録日2018-10-09
公開日2019-07-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria.
Mol.Microbiol., 111, 2019

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