4MW0
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![BU of 4mw0 by Molmil](/molmil-images/mine/4mw0) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea (Chem 1392) | 分子名称: | 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4MW6
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![BU of 4mw6 by Molmil](/molmil-images/mine/4mw6) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[2-(benzyloxy)-5-chloro-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1476) | 分子名称: | 1-(3-{[2-(benzyloxy)-5-chloro-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.558 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4MW5
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![BU of 4mw5 by Molmil](/molmil-images/mine/4mw5) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea (Chem 1415) | 分子名称: | 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.347 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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5XQ1
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![BU of 5xq1 by Molmil](/molmil-images/mine/5xq1) | Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | Fermitin family homolog 2,Integrin beta-3 | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.954 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8A5Y
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![BU of 8a5y by Molmil](/molmil-images/mine/8a5y) | S. cerevisiae apo unphosphorylated APC/C. | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | 著者 | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | 登録日 | 2022-06-16 | 公開日 | 2022-08-31 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states To Be Published
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8A61
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![BU of 8a61 by Molmil](/molmil-images/mine/8a61) | S. cerevisiae apo phosphorylated APC/C | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | 著者 | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | 登録日 | 2022-06-16 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C To Be Published
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8A3T
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![BU of 8a3t by Molmil](/molmil-images/mine/8a3t) | S. cerevisiae APC/C-Cdh1 complex | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | 著者 | Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J. | 登録日 | 2022-06-09 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex To Be Published
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5XQ0
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![BU of 5xq0 by Molmil](/molmil-images/mine/5xq0) | Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | Fermitin family homolog 2,Integrin beta-1, GLYCEROL | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7ON1
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![BU of 7on1 by Molmil](/molmil-images/mine/7on1) | Cenp-A nucleosome in complex with Cenp-C | 分子名称: | BJ4_G0006610.mRNA.1.CDS.1, BJ4_G0007000.mRNA.1.CDS.1, DNA (123-MER), ... | 著者 | Yan, K, Yang, J, Zhang, Z, Barford, D. | 登録日 | 2021-05-25 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cenp-A nucleosome in complex with Cenp-C To Be Published
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7U5H
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![BU of 7u5h by Molmil](/molmil-images/mine/7u5h) | |
7U5L
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![BU of 7u5l by Molmil](/molmil-images/mine/7u5l) | |
1AQC
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5XPZ
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![BU of 5xpz by Molmil](/molmil-images/mine/5xpz) | Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | Fermitin family homolog 2, GLYCEROL | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XPY
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![BU of 5xpy by Molmil](/molmil-images/mine/5xpy) | Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | ACETATE ION, Fermitin family homolog 2, GLYCEROL | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5Z09
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![BU of 5z09 by Molmil](/molmil-images/mine/5z09) | ST0452(Y97N)-UTP binding form | 分子名称: | Dual sugar-1-phosphate nucleotidylyltransferase, URIDINE 5'-TRIPHOSPHATE | 著者 | Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y. | 登録日 | 2017-12-19 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering Appl. Environ. Microbiol., 84, 2018
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5Z0A
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![BU of 5z0a by Molmil](/molmil-images/mine/5z0a) | ST0452(Y97N)-GlcNAc binding form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual sugar-1-phosphate nucleotidylyltransferase | 著者 | Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y. | 登録日 | 2017-12-19 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering Appl. Environ. Microbiol., 84, 2018
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5ZMN
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![BU of 5zmn by Molmil](/molmil-images/mine/5zmn) | Sulfur binding domain and SRA domain of ScoMcrA complexed with phosphorothioated DNA | 分子名称: | DNA (5'-D(*CP*CP*CP*GP*(GS)P*CP*CP*GP*GP*G)-3'), SULFATE ION, Uncharacterized protein McrA | 著者 | Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X. | 登録日 | 2018-04-04 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | 主引用文献 | Structural basis for the recognition of sulfur in phosphorothioated DNA. Nat Commun, 9, 2018
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5W3T
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6KZD
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![BU of 6kzd by Molmil](/molmil-images/mine/6kzd) | Crystal structure of TRKc in complex with 3-((6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl)ethynyl)- N-(3-isopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-2- methylbenzamide | 分子名称: | 3-[2-[6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl]ethynyl]-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-propan-2-yl-phenyl]benzamide, NT-3 growth factor receptor, PHOSPHATE ION | 著者 | Wang, Y, Zhang, Z.M. | 登録日 | 2019-09-23 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.708 Å) | 主引用文献 | Design, synthesis and biological evaluation of 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors. Eur.J.Med.Chem., 179, 2019
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6LYH
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![BU of 6lyh by Molmil](/molmil-images/mine/6lyh) | Crystal structure of tea N9-methyltransferase CkTcS in complex with SAH and 1,3,7-trimethyluric acid | 分子名称: | 1,3,7-trimethyl-9H-purine-2,6,8-trione, N-methyltransferase CkTcS, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Wang, Y, Zhang, Z.-M. | 登録日 | 2020-02-14 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15000319 Å) | 主引用文献 | Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea. Nat Commun, 11, 2020
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5GJB
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![BU of 5gjb by Molmil](/molmil-images/mine/5gjb) | Zika virus NS3 helicase in complex with ssRNA | 分子名称: | NS3 helicase, RNA (5'-R(*AP*GP*AP*UP*CP*AP*A)-3') | 著者 | Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H. | 登録日 | 2016-06-28 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Structural basis of Zika virus helicase in recognizing its substrates Protein Cell, 7, 2016
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8XV9
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![BU of 8xv9 by Molmil](/molmil-images/mine/8xv9) | Fedratinib-bound human SLC19A3 | 分子名称: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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8XV2
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![BU of 8xv2 by Molmil](/molmil-images/mine/8xv2) | Thiamine-bound human SLC19A3 | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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8XV5
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![BU of 8xv5 by Molmil](/molmil-images/mine/8xv5) | Pyridoxamine-bound human SLC19A3 | 分子名称: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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8GS9
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![BU of 8gs9 by Molmil](/molmil-images/mine/8gs9) | SARS-CoV-2 BA.2 spike RBD in complex bound with VacBB-551 | 分子名称: | Heavy chain of VacBB-551, Light chain of VacBB-551, Spike glycoprotein | 著者 | Liu, C.C, Ju, B, Shen, S.L, Zhang, Z. | 登録日 | 2022-09-05 | 公開日 | 2023-05-03 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination. Cell Rep, 42, 2023
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