Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1282 results

6XRQ
DownloadVisualize
BU of 6xrq by Molmil
Structural descriptions of ligand interactions to DNA and RNA quadruplexes folded from the non-coding region of Pseudorabies virus
Descriptor: 2,7-bis[3-(morpholin-4-yl)propyl]-4,9-bis{[3-(morpholin-4-yl)propyl]amino}benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, POTASSIUM ION, RNA (5' GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A-3')
Authors:Zhang, Y.S, Parkinson, G.N, Wei, D.G.
Deposit date:2020-07-13
Release date:2021-07-28
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of Pseudorabies virus.
Biochimie, 2024
5X87
DownloadVisualize
BU of 5x87 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation L177T
Descriptor: Bestrophin, ZINC ION
Authors:Zhang, Y, Chen, S, Yang, T.
Deposit date:2017-03-01
Release date:2017-11-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca2+-dependent Cl-currents in human RPE.
Elife, 6, 2017
4GKU
DownloadVisualize
BU of 4gku by Molmil
Crystal structure of beta lactamase in PET-15B
Descriptor: Beta-lactamase TEM
Authors:Zhang, Y, Cao, C.
Deposit date:2012-08-13
Release date:2012-10-10
Method:X-RAY DIFFRACTION (1.915 Å)
Cite:Crystal structure of beta lactamase in PET-15B
To be published
4F83
DownloadVisualize
BU of 4f83 by Molmil
Crystal structure of the receptor binding domain of botulinum neurotoxin mosaic serotype C/D with a tetraethylene glycol molecule bound on the Hcn sub-domain and a sulfate ion at the putative active site
Descriptor: GLYCEROL, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Zhang, Y, Buchko, G.W, Gardberg, A, Edwards, T.E, Sankaran, B, Robinson, H, Varnum, S.M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-05-16
Release date:2012-06-20
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D.
Biochimie, 95, 2013
4H6P
DownloadVisualize
BU of 4h6p by Molmil
Crystal structure of a putative chromate reductase from Gluconacetobacter hansenii, Gh-ChrR, containing a R101A substitution.
Descriptor: Chromate reductase, FLAVIN MONONUCLEOTIDE
Authors:Zhang, Y, Robinson, H, Buchko, G.W.
Deposit date:2012-09-19
Release date:2012-10-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.556 Å)
Cite:Mechanistic insights of chromate and uranyl reduction by the NADPH-dependent FMN reductase, ChrR, from Gluconacetobacter hansenii
To be Published
6N33
DownloadVisualize
BU of 6n33 by Molmil
Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622
Descriptor: 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor
Authors:Zhang, Y.
Deposit date:2018-11-14
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Nat Commun, 10, 2019
4HS4
DownloadVisualize
BU of 4hs4 by Molmil
Crystal structure of a putative chromate reductase from Gluconacetobacter hansenii, Gh-ChrR, containing a Y129N substitution.
Descriptor: Chromate reductase, FLAVIN MONONUCLEOTIDE
Authors:Zhang, Y, Robinson, H, Buchko, G.W.
Deposit date:2012-10-29
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic insights of chromate and uranyl reduction by the NADPH-dependent FMN reductase, ChrR, from Gluconacetobacter hansenii
To be Published
4NPU
DownloadVisualize
BU of 4npu by Molmil
Crystal Structure of HIV-1 Protease Multiple Mutant P51
Descriptor: Protease
Authors:Zhang, Y, Weber, I.T.
Deposit date:2013-11-22
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps.
Acs Chem.Biol., 9, 2014
5E17
DownloadVisualize
BU of 5e17 by Molmil
T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7)
Descriptor: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2015-09-29
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Science, 351, 2016
5E18
DownloadVisualize
BU of 5e18 by Molmil
T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)
Descriptor: DNA (28-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2015-09-29
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Science, 351, 2016
4NPT
DownloadVisualize
BU of 4npt by Molmil
Crystal Structure of HIV-1 Protease Multiple Mutant P51 Complexed with Darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, GLYCEROL, Protease
Authors:Zhang, Y, Weber, I.T.
Deposit date:2013-11-22
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps.
Acs Chem.Biol., 9, 2014
4OXW
DownloadVisualize
BU of 4oxw by Molmil
X-ray structure of a designed CISK-PX domain
Descriptor: SULFATE ION, designed CISK-PX domain
Authors:Zhang, Y, Shultis, D.D, Dodge, G.
Deposit date:2014-02-07
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:X-ray structure of a designed CISK-PX domain
To Be Published
9ATN
DownloadVisualize
BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
Descriptor: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
Authors:Zhang, Y, Zandian, M, Kutateladze, T.
Deposit date:2024-02-27
Release date:2024-06-19
Method:SOLUTION NMR
Cite:ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
6XNZ
DownloadVisualize
BU of 6xnz by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex
Descriptor: 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ...
Authors:Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
Deposit date:2020-07-05
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
6XNY
DownloadVisualize
BU of 6xny by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Paired-Form)
Descriptor: 12RSS integration strand (55-mer), 12RSS signal DNA top strand (34-mer), 23RSS integration strand (66-mer), ...
Authors:Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
Deposit date:2020-07-05
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
6Y5B
DownloadVisualize
BU of 6y5b by Molmil
5-HT3A receptor in Salipro (apo, asymmetric)
Descriptor: 5-hydroxytryptamine receptor 3A
Authors:Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M.
Deposit date:2020-02-25
Release date:2020-12-23
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers.
Nat Commun, 12, 2021
6XNX
DownloadVisualize
BU of 6xnx by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Dynamic-Form)
Descriptor: 12RSS integration strand DNA (55-MER), 12RSS signal top strand DNA (34-MER), 23RSS integration strand DNA (66-MER), ...
Authors:Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
Deposit date:2020-07-05
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
6Y59
DownloadVisualize
BU of 6y59 by Molmil
5-HT3A receptor in Salipro (apo, C5 symmetric)
Descriptor: 5-hydroxytryptamine receptor 3A
Authors:Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M.
Deposit date:2020-02-25
Release date:2020-12-23
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers.
Nat Commun, 12, 2021
6Y5A
DownloadVisualize
BU of 6y5a by Molmil
Serotonin-bound 5-HT3A receptor in Salipro
Descriptor: 5-hydroxytryptamine receptor 3A, SEROTONIN
Authors:Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M.
Deposit date:2020-02-25
Release date:2020-12-23
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers.
Nat Commun, 12, 2021
5WAN
DownloadVisualize
BU of 5wan by Molmil
Crystal Structure of a flavoenzyme RutA in the pyrimidine catabolic pathway
Descriptor: FLAVIN MONONUCLEOTIDE, GLYCEROL, Pyrimidine monooxygenase RutA, ...
Authors:Zhang, Y, Mukherjee, T, Abdelwahed, S, Begley, T.P, Ealick, S.E.
Deposit date:2017-06-26
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Catalysis of a flavoenzyme-mediated amide hydrolysis.
J. Am. Chem. Soc., 132, 2010
5X21
DownloadVisualize
BU of 5x21 by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM)
Descriptor: (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zhang, Y, Ebright, R.
Deposit date:2017-01-29
Release date:2017-07-05
Last modified:2022-10-12
Method:X-RAY DIFFRACTION (3.323 Å)
Cite:Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell, 169, 2017
6O7G
DownloadVisualize
BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
Descriptor: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2019-03-07
Release date:2019-05-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
5X22
DownloadVisualize
BU of 5x22 by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zhang, Y, Ebright, R.
Deposit date:2017-01-29
Release date:2017-07-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell, 169, 2017
6I5X
DownloadVisualize
BU of 6i5x by Molmil
Crystal structure of Aspergillus fumigatus phosphomannomutase
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Zhang, Y, Raimi, O.G, Ferenbach, A.T, van Aalten, D.M.F.
Deposit date:2018-11-15
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Aspergillus fumigatus phosphomannomutase
To Be Published
5UQ8
DownloadVisualize
BU of 5uq8 by Molmil
70S ribosome complex with dnaX mRNA stem-loop and E-site tRNA ("out" conformation)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zhang, Y, Hong, S, Skiniotis, G, Dunham, C.M.
Deposit date:2017-02-07
Release date:2018-03-07
Last modified:2018-03-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.
Structure, 26, 2018

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon