4F83
Crystal structure of the receptor binding domain of botulinum neurotoxin mosaic serotype C/D with a tetraethylene glycol molecule bound on the Hcn sub-domain and a sulfate ion at the putative active site
Summary for 4F83
Entry DOI | 10.2210/pdb4f83/pdb |
Descriptor | Type C neurotoxin, TETRAETHYLENE GLYCOL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, botulinum neurotoxin, mosaic serotype c/d, toxin |
Biological source | Clostridium botulinum |
Total number of polymer chains | 1 |
Total formula weight | 50172.41 |
Authors | Zhang, Y.,Buchko, G.W.,Gardberg, A.,Edwards, T.E.,Sankaran, B.,Robinson, H.,Varnum, S.M.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-05-16, release date: 2012-06-20, Last modification date: 2013-06-12) |
Primary citation | Zhang, Y.,Gardberg, A.S.,Edwards, T.E.,Sankaran, B.,Robinson, H.,Varnum, S.M.,Buchko, G.W. Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D. Biochimie, 95:1379-1385, 2013 Cited by PubMed: 23523511DOI: 10.1016/j.biochi.2013.03.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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