4F83

Crystal structure of the receptor binding domain of botulinum neurotoxin mosaic serotype C/D with a tetraethylene glycol molecule bound on the Hcn sub-domain and a sulfate ion at the putative active site

Summary for 4F83

Entry DOI	10.2210/pdb4f83/pdb
Descriptor	Type C neurotoxin, TETRAETHYLENE GLYCOL, SULFATE ION, ... (5 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, botulinum neurotoxin, mosaic serotype c/d, toxin
Biological source	Clostridium botulinum
Total number of polymer chains	1
Total formula weight	50172.41
Authors	Zhang, Y.,Buchko, G.W.,Gardberg, A.,Edwards, T.E.,Sankaran, B.,Robinson, H.,Varnum, S.M.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-05-16, release date: 2012-06-20, Last modification date: 2013-06-12)
Primary citation	Zhang, Y.,Gardberg, A.S.,Edwards, T.E.,Sankaran, B.,Robinson, H.,Varnum, S.M.,Buchko, G.W. Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D. Biochimie, 95:1379-1385, 2013 Cited by PubMed: 23523511 DOI: 10.1016/j.biochi.2013.03.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation