7LLL
| Exendin-4-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | 分子名称: | Exendin-4, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | 登録日 | 2021-02-04 | 公開日 | 2022-01-12 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation. Nat Commun, 13, 2022
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6LZ7
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6LZ3
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5E6P
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8FLK
| Cryo-EM structure of STING oligomer bound to cGAMP and NVS-STG2 | 分子名称: | 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, cGAMP | 著者 | Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y. | 登録日 | 2022-12-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Activation of human STING by a molecular glue-like compound. Nat.Chem.Biol., 20, 2024
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8FLM
| Cryo-EM structure of STING oligomer bound to cGAMP, NVS-STG2 and C53 | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, ... | 著者 | Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y. | 登録日 | 2022-12-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Activation of human STING by a molecular glue-like compound. Nat.Chem.Biol., 20, 2024
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5WTA
| Crystal Structure of Staphylococcus aureus SdrE apo form | 分子名称: | Serine-aspartate repeat-containing protein E | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | 登録日 | 2016-12-10 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Biochem. J., 474, 2017
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5WTB
| Complex Structure of Staphylococcus aureus SdrE with human complement factor H | 分子名称: | Peptide from Complement factor H, Serine-aspartate repeat-containing protein E | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | 登録日 | 2016-12-10 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Biochem. J., 474, 2017
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5EWU
| Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A | 分子名称: | BENZOIC ACID, MAGNESIUM ION, Magnesium-chelatase subunit ChlH, ... | 著者 | Chen, Z, Zhang, X, Liu, Y, Jiang, L. | 登録日 | 2015-11-21 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A To Be Published
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8QOT
| Structure of the mu opioid receptor bound to the antagonist nanobody NbE | 分子名称: | Anti-Fab Nanobody, Mu-type opioid receptor, NabFab HC, ... | 著者 | Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Manglik, A, Ballet, S, Boland, A, Stoeber, M. | 登録日 | 2023-09-29 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist. Biorxiv, 2023
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6A6B
| cryo-em structure of alpha-synuclein fiber | 分子名称: | Alpha-synuclein | 著者 | Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X. | 登録日 | 2018-06-27 | 公開日 | 2018-07-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy Cell Res., 28, 2018
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4Q9V
| Crystal structure of TIPE3 | 分子名称: | CHLORIDE ION, SULFATE ION, Tumor necrosis factor alpha-induced protein 8-like protein 3 | 著者 | Wu, J, Zhang, X, Chen, Y.H, Shi, Y. | 登録日 | 2014-05-02 | 公開日 | 2014-10-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer. Cancer Cell, 26, 2014
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6BP7
| Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2 | 分子名称: | Major vault protein | 著者 | Ding, K, Zhang, X, Mrazek, J, Kickhoefer, V.A, Lai, M, Ng, H.L, Yang, O.O, Rome, L.H, Zhou, Z.H. | 登録日 | 2017-11-22 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Solution Structures of Engineered Vault Particles. Structure, 26, 2018
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6BZE
| Cryo-EM structure of BCL10 CARD filament | 分子名称: | B-cell lymphoma/leukemia 10 | 著者 | David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H. | 登録日 | 2017-12-23 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BP8
| Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1 | 分子名称: | Major vault protein | 著者 | Ding, K, Zhang, X, Mrazek, J, Kickhoefer, V.A, Lai, M, Ng, H.L, Yang, O.O, Rome, L.H, Zhou, Z.H. | 登録日 | 2017-11-22 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Solution Structures of Engineered Vault Particles. Structure, 26, 2018
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5X5S
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5Y9P
| Staphylococcus aureus RNase HII | 分子名称: | GLYCEROL, Ribonuclease HII | 著者 | Hang, T, Wu, M, Zhang, X. | 登録日 | 2017-08-26 | 公開日 | 2018-08-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into a novel functional dimer of Staphylococcus aureus RNase HII Biochem. Biophys. Res. Commun., 503, 2018
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4HIL
| 1.25A Resolution Structure of Rat Type B Cytochrome b5 | 分子名称: | Cytochrome b5 type B, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION | 著者 | Lovell, S, Battaile, K.P, Parthasarathy, S, Sun, N, Terzyan, S, Zhang, X, Rivera, M, Kuczera, K, Benson, D.R. | 登録日 | 2012-10-11 | 公開日 | 2013-10-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | 1.25A Resolution Structure of Rat Type B Cytochrome b5 To be Published
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4HIN
| 2.4A Resolution Structure of Bovine Cytochrome b5 (S71L) | 分子名称: | COPPER (II) ION, Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Battaile, K.P, Parthasarathy, S, Sun, N, Terzyan, S, Zhang, X, Rivera, M, Kuczera, K, Benson, D.R. | 登録日 | 2012-10-11 | 公開日 | 2013-10-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 2.4A Resolution Structure of Bovine Cytochrome b5 (S71L) To be Published
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4IP3
| Complex structure of OspI and Ubc13 | 分子名称: | ORF169b, Ubiquitin-conjugating enzyme E2 N | 著者 | Fu, P, Jin, M, Zhang, X, Xu, L, Xia, Z, Zhu, Y. | 登録日 | 2013-01-09 | 公開日 | 2013-03-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure Analysis of Ubc13 Inactivation To be Published
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4JPN
| Bacteriophage phiX174 H protein residues 143-221 | 分子名称: | Minor spike protein H | 著者 | Sun, L, Young, L.N, Boudko, S.B, Fokine, A, Zhang, X, Rossmann, M.G, Fane, B.A. | 登録日 | 2013-03-19 | 公開日 | 2013-12-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Icosahedral bacteriophage Phi X174 forms a tail for DNA transport during infection. Nature, 505, 2014
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4JPP
| Bacteriophage phiX174 H protein residues 143-282 | 分子名称: | Minor spike protein H | 著者 | Sun, L, Young, L.N, Boudko, S.B, Fokine, A, Zhang, X, Rossmann, M.G, Fane, B.A. | 登録日 | 2013-03-19 | 公開日 | 2013-12-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Icosahedral bacteriophage Phi X174 forms a tail for DNA transport during infection. Nature, 505, 2014
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4LDT
| The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ... | 著者 | Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C. | 登録日 | 2013-06-25 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat.Struct.Mol.Biol., 20, 2013
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6NT9
| Cryo-EM structure of the complex between human TBK1 and chicken STING | 分子名称: | Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | 登録日 | 2019-01-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of STING binding with and phosphorylation by TBK1. Nature, 567, 2019
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8H3L
| Crystal Structure of SARS-CoV-2 Main Protease (Mpro) Double Mutant (T21I and E166V) in Complex with Inhibitor Enstrelvir | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | 著者 | Wang, H, Lin, M, Duan, Y, Zhang, X, Zhou, H, Bian, Q, Liu, X, Rao, Z, Yang, H. | 登録日 | 2022-10-08 | 公開日 | 2023-10-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature, 622, 2023
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