4R2C
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![BU of 4r2c by Molmil](/molmil-images/mine/4r2c) | Egr1/Zif268 zinc fingers in complex with hydroxymethylated DNA | 分子名称: | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5HC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5HC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), Early growth response protein 1, ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-11 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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4N5G
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![BU of 4n5g by Molmil](/molmil-images/mine/4n5g) | Crystal Structure of RXRa LBD complexed with a synthetic modulator K8012 | 分子名称: | 5-(2-{(1Z)-5-fluoro-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole, Retinoic acid receptor RXR-alpha | 著者 | Aleshin, A.E, Su, Y, Zhang, X, Liddington, R.C. | 登録日 | 2013-10-09 | 公開日 | 2014-05-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site. Chem.Biol., 21, 2014
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4R2S
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![BU of 4r2s by Molmil](/molmil-images/mine/4r2s) | Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-12 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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8B4J
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7YL7
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![BU of 7yl7 by Molmil](/molmil-images/mine/7yl7) | Structure of hIAPP-TF-type3 | 分子名称: | Islet amyloid polypeptide | 著者 | Li, D, Zhang, X. | 登録日 | 2022-07-25 | 公開日 | 2022-12-28 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core. Iscience, 25, 2022
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3LQ9
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![BU of 3lq9 by Molmil](/molmil-images/mine/3lq9) | Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR | 分子名称: | DNA-damage-inducible transcript 4 protein | 著者 | Vega-Rubin-de-Celis, S, Abdallah, Z, Brugarolas, J, Zhang, X. | 登録日 | 2010-02-08 | 公開日 | 2010-03-09 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analysis and functional implications of the negative mTORC1 regulator REDD1. Biochemistry, 49, 2010
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7OZR
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![BU of 7ozr by Molmil](/molmil-images/mine/7ozr) | |
6A6B
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![BU of 6a6b by Molmil](/molmil-images/mine/6a6b) | cryo-em structure of alpha-synuclein fiber | 分子名称: | Alpha-synuclein | 著者 | Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X. | 登録日 | 2018-06-27 | 公開日 | 2018-07-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy Cell Res., 28, 2018
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4GKG
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![BU of 4gkg by Molmil](/molmil-images/mine/4gkg) | Crystal structure of the S-Helix Linker | 分子名称: | C4-dicarboxylate transport sensor protein dctB, PHOSPHATE ION | 著者 | Liu, J.W, Lu, D, Sun, Y.J, Wen, J, Yang, Y, Yang, J.G, Wei, X.L, Zhang, X.D, Wang, Y.P. | 登録日 | 2012-08-11 | 公開日 | 2013-08-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | 主引用文献 | Crystal structure of the S-Helix Linker To be Published
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5Y9P
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![BU of 5y9p by Molmil](/molmil-images/mine/5y9p) | Staphylococcus aureus RNase HII | 分子名称: | GLYCEROL, Ribonuclease HII | 著者 | Hang, T, Wu, M, Zhang, X. | 登録日 | 2017-08-26 | 公開日 | 2018-08-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into a novel functional dimer of Staphylococcus aureus RNase HII Biochem. Biophys. Res. Commun., 503, 2018
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8CXH
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![BU of 8cxh by Molmil](/molmil-images/mine/8cxh) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | 分子名称: | Ankyrin repeat family A protein 2,Envelope E protein, C10 heavy chain, C10 light chain, ... | 著者 | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | 登録日 | 2022-05-21 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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8CXG
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![BU of 8cxg by Molmil](/molmil-images/mine/8cxg) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | 分子名称: | Ankyrin repeat family A protein 2,Envelope E protein, C8 scFv heavy chain, C8 scFv light chain, ... | 著者 | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | 登録日 | 2022-05-21 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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8CXI
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![BU of 8cxi by Molmil](/molmil-images/mine/8cxi) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | 分子名称: | A11 heavy chain, A11 light chain, Ankyrin repeat family A protein 2,Envelope E protein, ... | 著者 | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | 登録日 | 2022-05-21 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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4GYV
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![BU of 4gyv by Molmil](/molmil-images/mine/4gyv) | Crystal structure of the DH domain of FARP2 | 分子名称: | FERM, RhoGEF and pleckstrin domain-containing protein 2 | 著者 | He, X, Zhang, X. | 登録日 | 2012-09-05 | 公開日 | 2013-03-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2. Structure, 21, 2013
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4H6Y
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![BU of 4h6y by Molmil](/molmil-images/mine/4h6y) | |
3CTM
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![BU of 3ctm by Molmil](/molmil-images/mine/3ctm) | Crystal Structure of a Carbonyl Reductase from Candida Parapsilosis with anti-Prelog Stereo-specificity | 分子名称: | Carbonyl Reductase | 著者 | Zhang, R, Zhu, G, Li, X, Xu, Y, Zhang, X.C, Rao, Z. | 登録日 | 2008-04-14 | 公開日 | 2008-05-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity. Protein Sci., 17, 2008
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3MHS
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![BU of 3mhs by Molmil](/molmil-images/mine/3mhs) | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... | 著者 | Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. | 登録日 | 2010-04-08 | 公開日 | 2010-04-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
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3MHH
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![BU of 3mhh by Molmil](/molmil-images/mine/3mhh) | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module | 分子名称: | Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... | 著者 | Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. | 登録日 | 2010-04-08 | 公開日 | 2010-04-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
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7M0R
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![BU of 7m0r by Molmil](/molmil-images/mine/7m0r) | Cryo-EM structure of the Sema3A/PlexinA4/Neuropilin 1 complex | 分子名称: | CALCIUM ION, Neuropilin-1, Plexin-A4, ... | 著者 | Lu, D, Shang, G, He, X, Bai, X, Zhang, X. | 登録日 | 2021-03-11 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Architecture of the Sema3A/PlexinA4/Neuropilin tripartite complex. Nat Commun, 12, 2021
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4GZN
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![BU of 4gzn by Molmil](/molmil-images/mine/4gzn) | Mouse ZFP57 zinc fingers in complex with methylated DNA | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Liu, Y, Zhang, X, Cheng, X. | 登録日 | 2012-09-06 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | 主引用文献 | An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes Dev., 26, 2012
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4GZU
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![BU of 4gzu by Molmil](/molmil-images/mine/4gzu) | |
7SII
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![BU of 7sii by Molmil](/molmil-images/mine/7sii) | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | 著者 | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | 登録日 | 2021-10-14 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Activation of STING by targeting a pocket in the transmembrane domain. Nature, 604, 2022
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3OZZ
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![BU of 3ozz by Molmil](/molmil-images/mine/3ozz) | |
4JGC
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![BU of 4jgc by Molmil](/molmil-images/mine/4jgc) | Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC) | 分子名称: | 4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid, G/T mismatch-specific thymine DNA glycosylase, oligonucleotide, ... | 著者 | Hashimoto, H, Zhang, X, Cheng, X. | 登録日 | 2013-02-28 | 公開日 | 2013-05-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.582 Å) | 主引用文献 | Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH. Dna Repair, 12, 2013
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4TOS
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![BU of 4tos by Molmil](/molmil-images/mine/4tos) | Crystal structure of Tankyrase 1 with 355 | 分子名称: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | 著者 | Chen, H, Zhang, X, Lum, l, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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