3LQ9

Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR

Summary for 3LQ9

Entry DOI	10.2210/pdb3lq9/pdb
Descriptor	DNA-damage-inducible transcript 4 protein (2 entities in total)
Functional Keywords	redd1 ddit4 mtor, hypoxia, cancer, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion : Q9NX09
Total number of polymer chains	2
Total formula weight	29661.80
Authors	Vega-Rubin-de-Celis, S.,Abdallah, Z.,Brugarolas, J.,Zhang, X. (deposition date: 2010-02-08, release date: 2010-03-09, Last modification date: 2017-11-01)
Primary citation	Vega-Rubin-de-Celis, S.,Abdallah, Z.,Kinch, L.,Grishin, N.V.,Brugarolas, J.,Zhang, X. Structural analysis and functional implications of the negative mTORC1 regulator REDD1. Biochemistry, 49:2491-2501, 2010 Cited by PubMed: 20166753 DOI: 10.1021/bi902135e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation