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PDB: 287 件
7W3H
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BU of 7w3h by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W38
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Structure of USP14-bound human 26S proteasome in state EA2.0_UBL
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W39
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BU of 7w39 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.1_UBL
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3J
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BU of 7w3j by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3C
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BU of 7w3c by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3A
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BU of 7w3a by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3K
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BU of 7w3k by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3M
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BU of 7w3m by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-18
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3I
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BU of 7w3i by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-18
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7YPG
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BU of 7ypg by Molmil
Cryo-EM structure of amyloid fibril formed by tau (297-391)
分子名称: Isoform Tau-E of Microtubule-associated protein tau
著者Zhang, S.Q, Li, X, Liu, C.
登録日2022-08-03
公開日2022-12-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
5ZHH
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BU of 5zhh by Molmil
Structure of Inositol monophosphatase from Anabaena (Nostoc) sp. PCC 7120
分子名称: Inositol-1-monophosphatase
著者Zhang, S.R, Wang, F.K.
登録日2018-03-13
公開日2019-04-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure of Inositol monophosphatase from Anabaena (Nostoc) sp. PCC 7120
To Be Published
7WAZ
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BU of 7waz by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at ts loading state
分子名称: NTS-DNA, RNA (115-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB0
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BU of 7wb0 by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state with flexible H2 domain
分子名称: NTS-DNA, RNA (115-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB1
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BU of 7wb1 by Molmil
PlmCasX-sgRNAv2-dsDNA ternary complex at nts loading state
分子名称: NTS-DNA, RNA (121-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAY
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BU of 7way by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state
分子名称: DNA (27-MER), DNA (33-MER), RNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7YEO
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BU of 7yeo by Molmil
Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c
分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Uncharacterized trans-sulfuration enzyme C23A1.14c
著者Zhang, S.J.
登録日2022-07-06
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c
To Be Published
7Y5G
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BU of 7y5g by Molmil
Cryo-EM structure of a eukaryotic ZnT8 in the presence of zinc
分子名称: ZINC ION, Zinc transporter 8
著者Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X.
登録日2022-06-17
公開日2022-12-14
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
J.Struct.Biol., 215, 2022
7Y5H
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BU of 7y5h by Molmil
Cryo-EM structure of a eukaryotic ZnT8 at a low pH
分子名称: ZINC ION, Zinc transporter 8
著者Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X.
登録日2022-06-17
公開日2022-12-14
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
J.Struct.Biol., 215, 2022
7VG8
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BU of 7vg8 by Molmil
TYLCV Rep-DNA
分子名称: DNA (5'-((DT)P*(DA)P*(DA)P*(DT)P*(DA)P*(DT)P*(DT)P*(DA)*(DC)P*)-3'), MANGANESE (II) ION, Replication-associated protein
著者Zhang, S.Y, Wang, C.N.
登録日2021-09-14
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献structure of TYLCV Rep complexed with ssDNA
To Be Published
4UCG
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BU of 4ucg by Molmil
NmeDAH7PS R126S variant
分子名称: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, ...
著者Cross, P.J, Heyes, L.C, Zhang, S, Nazmi, A.R, Parker, E.J.
登録日2014-12-03
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Functional Unit of Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase is Dimeric.
Plos One, 11, 2016
8X6Z
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BU of 8x6z by Molmil
1-naphthylamine GS from Pseudomonas sp. JS3066
分子名称: Glutamine synthetase, MANGANESE (II) ION
著者Zhou, N.Y, Zhang, S.T.
登録日2023-11-22
公開日2024-01-03
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of 1-naphthylamine glutamine synthetase at 2.95 Angstroms resolution.
To Be Published
7OQ6
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BU of 7oq6 by Molmil
Crystal structure of cytochrome P450 Sas16 from Streptomyces asterosporus
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION
著者Zhang, L, Zhang, S, Bechthold, A, Einsle, O.
登録日2021-06-02
公開日2022-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate.
Acta Pharm Sin B, 13, 2023
6QNS
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BU of 6qns by Molmil
Crystal structure of the binding domain of Botulinum Neurotoxin type B mutant I1248W/V1249W in complex with human synaptotagmin 1 and GD1a receptors
分子名称: Botulinum neurotoxin type B, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Synaptotagmin-1
著者Masuyer, G, Yin, L, Zhang, S, Miyashita, S.I, Dong, M, Stenmark, P.
登録日2019-02-12
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.
Plos Biol., 18, 2020
2XNI
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BU of 2xni by Molmil
Protein-ligand complex of a novel macrocyclic HCV NS3 protease inhibitor derived from amino cyclic boronates
分子名称: (1-{[(10-tert-butyl-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19,23,23a-tetradecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosin-7(3H)-yl)carbonyl]amino}-3-hydroxypropyl)(trihydroxy)borate(1-), MAGNESIUM ION, NS3 PROTEASE, ...
著者Li, X, Zhang, Y.-K, Liu, Y, Ding, C.Z, Zhou, Y, Li, Q, Plattner, J.J, Baker, S.J, Zhang, S, Kazmierski, W.M, Wright, L.L, Smith, G.K, Grimes, R.M, Crosby, R.M, Creech, K.L, Carballo, L.H, Slater, M.J, Jarvest, R.L, Thommes, P, Hubbard, J.A, Convery, M.A, Nassau, P.M, McDowell, W, Skarzynski, T.J, Qian, X, Fan, D, Liao, L, Ni, Z.-J, Pennicott, L.E, Zou, W, Wright, J.
登録日2010-08-02
公開日2011-08-17
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel Macrocyclic Hcv Ns3 Protease Inhibitors Derived from Alpha-Amino Cyclic Boronates.
Bioorg.Med.Chem.Lett., 20, 2010
5JYY
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BU of 5jyy by Molmil
Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ...
著者Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X.
登録日2016-05-15
公開日2016-06-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016

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