7W3K
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14
This is a non-PDB format compatible entry.
Summary for 7W3K
Entry DOI | 10.2210/pdb7w3k/pdb |
EMDB information | 32283 |
Descriptor | 26S protease regulatory subunit 7, Isoform Long of Proteasome subunit alpha type-1, Proteasome subunit alpha type-3, ... (37 entities in total) |
Functional Keywords | proteasome, aaa-atpase, deubiquitinase, usp14, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 48 |
Total formula weight | 1731853.56 |
Authors | |
Primary citation | Zhang, S.,Zou, S.,Yin, D.,Zhao, L.,Finley, D.,Wu, Z.,Mao, Y. USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605:567-574, 2022 Cited by PubMed: 35477760DOI: 10.1038/s41586-022-04671-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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