6DCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dcv by Molmil](/molmil-images/mine/6dcv) | Crystal structure of human anti-tau antibody CBTAU-27.1 | Descriptor: | GLYCEROL, Light chain of CBTAU27.1 Fab, heavy chain of CBTAU-27.1 Fab | Authors: | Zhu, X, Zhang, H, Wilson, I.A. | Deposit date: | 2018-05-08 | Release date: | 2018-06-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018
|
|
1M4M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m4m by Molmil](/molmil-images/mine/1m4m) | Mouse Survivin | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, ZINC ION | Authors: | Muchmore, S.W, Chen, J, Jakob, C, Zakula, D, Matayoshi, E.D, Wu, W, Zhang, H, Li, F, Ng, S.C, Altieri, D.C. | Deposit date: | 2002-07-03 | Release date: | 2002-09-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | CRYSTAL STRUCTURE AND MUTAGENIC ANALYSIS OF THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN MOL.CELL, 6, 2000
|
|
1M32
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m32 by Molmil](/molmil-images/mine/1m32) | Crystal Structure of 2-aminoethylphosphonate Transaminase | Descriptor: | 2-aminoethylphosphonate-pyruvate aminotransferase, PHOSPHATE ION, PHOSPHONOACETALDEHYDE, ... | Authors: | Chen, C.C.H, Zhang, H, Kim, A.D, Howard, A, Sheldrick, G.M, Mariano-Dunnaway, D, Herzberg, O. | Deposit date: | 2002-06-26 | Release date: | 2002-11-20 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Degradation Pathway of the Phosphonate Ciliatine: Crystal Structure of 2-Aminoethylphosphonate Transaminase Biochemistry, 41, 2002
|
|
5H4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h4b by Molmil](/molmil-images/mine/5h4b) | Crystal structure of Cbln4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-4 | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | Deposit date: | 2016-10-31 | Release date: | 2017-09-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
|
|
4YVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yvx by Molmil](/molmil-images/mine/4yvx) | Crystal structure of AKR1C3 complexed with glimepiride | Descriptor: | 3-ethyl-4-methyl-N-[2-(4-{[(cis-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-car boxamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhao, Y, Zheng, X, Zhang, H, Hu, X. | Deposit date: | 2015-03-20 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
|
|
4YVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yvp by Molmil](/molmil-images/mine/4yvp) | Crystal Structure of AKR1C1 complexed with glibenclamide | Descriptor: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhao, Y, Zheng, X, Zhang, H, Hu, X. | Deposit date: | 2015-03-20 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
|
|
5HFJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hfj by Molmil](/molmil-images/mine/5hfj) | crystal structure of M1.HpyAVI-SAM complex | Descriptor: | Adenine specific DNA methyltransferase (DpnA), S-ADENOSYLMETHIONINE | Authors: | Ma, B, Liu, W, Zhang, H. | Deposit date: | 2016-01-07 | Release date: | 2016-11-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori Oncotarget, 7, 2016
|
|
5VJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vjx by Molmil](/molmil-images/mine/5vjx) | Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor | Descriptor: | CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput | Authors: | Hou, Z, Su, L, Pei, J, Grishin, N.V, Zhang, H. | Deposit date: | 2017-04-20 | Release date: | 2017-12-06 | Last modified: | 2020-01-29 | Method: | X-RAY DIFFRACTION (2.695 Å) | Cite: | Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor. Structure, 25, 2017
|
|
5VJI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vji by Molmil](/molmil-images/mine/5vji) | Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor | Descriptor: | CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput | Authors: | Hou, Z, Su, L, Pei, J, Grishin, N.V, Zhang, H. | Deposit date: | 2017-04-19 | Release date: | 2017-06-07 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor. Structure, 25, 2017
|
|
4OQ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oq6 by Molmil](/molmil-images/mine/4oq6) | Crystal Structure of Human MCL-1 Bound to Inhibitor 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid | Descriptor: | 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Petros, A.M, Swann, S.L, Song, D, Swinger, K, Park, C, Zhang, H, Wendt, M.D, Kunzer, A.R, Souers, A.J, Sun, C. | Deposit date: | 2014-02-07 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg.Med.Chem.Lett., 24, 2014
|
|
2L6E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l6e by Molmil](/molmil-images/mine/2l6e) | NMR Structure of the monomeric mutant C-terminal domain of HIV-1 Capsid in complex with stapled peptide Inhibitor | Descriptor: | Capsid protein p24, NYAD-13 stapled peptide inhibitor | Authors: | Bhattacharya, S, Zhang, H, Debnath, A.K, Cowburn, D. | Deposit date: | 2010-11-18 | Release date: | 2010-12-29 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid. J.Biol.Chem., 283, 2008
|
|
5GYY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gyy by Molmil](/molmil-images/mine/5gyy) | Plant receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S-locus protein 11, S-receptor kinase SRK9 | Authors: | Ma, R, Han, Z, Hu, Z, Lin, G, Gong, X, Zhang, H, June, N, Chai, J. | Deposit date: | 2016-09-24 | Release date: | 2017-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.351 Å) | Cite: | Plant receptor complex at 2.35 Angstroms resolution To Be Published
|
|
5GNI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gni by Molmil](/molmil-images/mine/5gni) | |
5H49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h49 by Molmil](/molmil-images/mine/5h49) | Crystal structure of Cbln1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | Deposit date: | 2016-10-31 | Release date: | 2017-09-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
|
|
7CX4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cx4 by Molmil](/molmil-images/mine/7cx4) | Cryo-EM structure of the Evatanepag-bound EP2-Gs complex | Descriptor: | 2-[3-[[(4-~{tert}-butylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y. | Deposit date: | 2020-09-01 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype. Sci Adv, 7, 2021
|
|
7CX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cx3 by Molmil](/molmil-images/mine/7cx3) | Cryo-EM structure of the Taprenepag-bound EP2-Gs complex | Descriptor: | 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y. | Deposit date: | 2020-09-01 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype. Sci Adv, 7, 2021
|
|
7CX2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cx2 by Molmil](/molmil-images/mine/7cx2) | Cryo-EM structure of the PGE2-bound EP2-Gs complex | Descriptor: | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y. | Deposit date: | 2020-09-01 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype. Sci Adv, 7, 2021
|
|
6K4Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k4q by Molmil](/molmil-images/mine/6k4q) | Crystal structure of xCas9 in complex with sgRNA and DNA (CGG PAM) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*CP*GP*GP*TP*AP*TP*TP*G)-3'), ... | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | Deposit date: | 2019-05-26 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17, 2019
|
|
4OPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4opn by Molmil](/molmil-images/mine/4opn) | |
4W6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4w6q by Molmil](/molmil-images/mine/4w6q) | Glycosyltransferase C from Streptococcus agalactiae | Descriptor: | SERINE, URIDINE-5'-DIPHOSPHATE, glucosyltransferase | Authors: | Zhu, F, Zhang, H, Wu, H. | Deposit date: | 2014-08-20 | Release date: | 2015-07-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A conserved domain is crucial for acceptor substrate binding in a family of glucosyltransferases. J.Bacteriol., 197, 2015
|
|
2QJT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qjt by Molmil](/molmil-images/mine/2qjt) | Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase complexed with AMP and MN ion from Francisella tularensis | Descriptor: | ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, Nicotinamide-nucleotide adenylyltransferase | Authors: | Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H. | Deposit date: | 2007-07-09 | Release date: | 2008-03-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism. Structure, 16, 2008
|
|
2R5W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r5w by Molmil](/molmil-images/mine/2r5w) | Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase from Francisella tularensis | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Nicotinamide-nucleotide adenylyltransferase | Authors: | Huang, N, Sorci, L, Zhang, X, Brautigan, C, Li, X, Raffaelli, N, Grishin, N, Osterman, A, Zhang, H. | Deposit date: | 2007-09-04 | Release date: | 2008-03-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism. Structure, 16, 2008
|
|
7CQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cqz by Molmil](/molmil-images/mine/7cqz) | crystal structure of mouse FAM46C (TENT5C) | Descriptor: | CHLORIDE ION, GLYCEROL, Terminal nucleotidyltransferase 5C | Authors: | Hu, J.L, Zhang, H, Gao, S. | Deposit date: | 2020-08-12 | Release date: | 2021-06-09 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.34969759 Å) | Cite: | Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C. Cancer Commun (Lond), 41, 2021
|
|
1NUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nur by Molmil](/molmil-images/mine/1nur) | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE | Descriptor: | FKSG76, SULFATE ION | Authors: | Zhang, X, Kurnasov, O.V, Karthikeyan, S, Grishin, N.V, Osterman, A.L, Zhang, H. | Deposit date: | 2003-02-01 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS J.Biol.Chem., 278, 2003
|
|
1NUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nup by Molmil](/molmil-images/mine/1nup) | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE COMPLEX WITH NMN | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, FKSG76, SULFATE ION | Authors: | Zhang, X, Kurnasov, O.V, Karthikeyan, S, Grishin, N.V, Osterman, A.L, Zhang, H. | Deposit date: | 2003-02-01 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS J.Biol.Chem., 278, 2003
|
|