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PDB: 721 results

8JMX
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The crystal structure of human aurka kinase domain in complex with AURKA-A2
Descriptor: 5-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde, Aurora kinase A
Authors:Zhu, C.J, Zhang, Z.M.
Deposit date:2023-06-05
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.95020175 Å)
Cite:Multitarget inhibitors/probes that target LRRK2 and AURORA A kinases noncovalently and covalently.
Chem.Commun.(Camb.), 59, 2023
7ON1
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BU of 7on1 by Molmil
Cenp-A nucleosome in complex with Cenp-C
Descriptor: BJ4_G0006610.mRNA.1.CDS.1, BJ4_G0007000.mRNA.1.CDS.1, DNA (123-MER), ...
Authors:Yan, K, Yang, J, Zhang, Z, Barford, D.
Deposit date:2021-05-25
Release date:2021-07-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cenp-A nucleosome in complex with Cenp-C
To Be Published
9AVL
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BU of 9avl by Molmil
Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs
Descriptor: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
Deposit date:2024-03-04
Release date:2024-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AVG
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BU of 9avg by Molmil
Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs
Descriptor: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
Deposit date:2024-03-02
Release date:2024-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AXF
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BU of 9axf by Molmil
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
Authors:Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
Deposit date:2024-03-06
Release date:2024-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AYF
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BU of 9ayf by Molmil
Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
Authors:Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
Deposit date:2024-03-07
Release date:2024-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9ASB
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BU of 9asb by Molmil
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs
Descriptor: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
Deposit date:2024-02-24
Release date:2024-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
3OMH
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BU of 3omh by Molmil
Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide
Descriptor: Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22
Authors:Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
Deposit date:2010-08-26
Release date:2011-06-29
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate.
J.Biol.Chem., 286, 2011
7R5R
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BU of 7r5r by Molmil
Structure of the human CCAN CENP-A alpha-satellite complex
Descriptor: Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ...
Authors:Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
Deposit date:2022-02-11
Release date:2022-04-27
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7R5V
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BU of 7r5v by Molmil
Structure of the human CCAN CENP-A alpha-satellite complex
Descriptor: Centromere protein H, Centromere protein I, Centromere protein K, ...
Authors:Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
Deposit date:2022-02-11
Release date:2022-04-27
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
8GS3
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BU of 8gs3 by Molmil
Cryo-EM structure of human Neuroligin 3
Descriptor: Neuroligin-3
Authors:Zhang, H, Zhang, Z, Hou, M.
Deposit date:2022-09-04
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Front Endocrinol, 13, 2022
8OVX
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BU of 8ovx by Molmil
Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus
Descriptor: Inner kinetochore subunit AME1, Inner kinetochore subunit CTF19, Inner kinetochore subunit MCM21, ...
Authors:Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S.
Deposit date:2023-04-26
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OVW
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BU of 8ovw by Molmil
Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA
Descriptor: C0N3 DNA, Centromere-binding protein 1, Inner kinetochore subunit AME1, ...
Authors:Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
Deposit date:2023-04-26
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OW0
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BU of 8ow0 by Molmil
Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome
Descriptor: C0N3 DNA, Centromere-binding protein 1, Histone H2A.1, ...
Authors:Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
Deposit date:2023-04-26
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8A5Y
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BU of 8a5y by Molmil
S. cerevisiae apo unphosphorylated APC/C.
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
Authors:Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
Deposit date:2022-06-16
Release date:2022-08-31
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
8A61
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BU of 8a61 by Molmil
S. cerevisiae apo phosphorylated APC/C
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
Authors:Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
Deposit date:2022-06-16
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
8A3T
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BU of 8a3t by Molmil
S. cerevisiae APC/C-Cdh1 complex
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
Authors:Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J.
Deposit date:2022-06-09
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
6J3X
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BU of 6j3x by Molmil
The Structure of Maltooligosaccharide-forming Amylase from Pseudomonas saccharophila STB07 with Maltotriose
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glucan 1,4-alpha-maltotetraohydrolase, ...
Authors:Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H.
Deposit date:2019-01-06
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Maltotetraose-forming amylase from Pseudomonas saccharophila STB07
To Be Published
8HPA
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BU of 8hpa by Molmil
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ...
Authors:Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C.
Deposit date:2022-12-12
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structure of DNA replication machinery from human monkeypox virus
To Be Published
3J2M
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BU of 3j2m by Molmil
The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the extended T4 tail
Descriptor: Tail connector protein Gp15, Tail sheath protein Gp18
Authors:Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
Deposit date:2012-11-09
Release date:2013-03-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15 Å)
Cite:The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
8WHA
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BU of 8wha by Molmil
Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WH5
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BU of 8wh5 by Molmil
Structure of DDM1-nucleosome complex in the apo state
Descriptor: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WHB
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BU of 8whb by Molmil
Structure of nucleosome core particle of Arabidopsis thaliana
Descriptor: DNA (antisense strand), DNA (sense strand), Histone H2A.6, ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WH9
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BU of 8wh9 by Molmil
Structure of DDM1-nucleosome complex in ADP-BeFx state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
6IYG
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BU of 6iyg by Molmil
The Structure of Maltooligosaccharide-forming Amylase from Pseudomonas saccharophila STB07 with Maltotetraose
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glucan 1,4-alpha-maltotetraohydrolase, ...
Authors:Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H.
Deposit date:2018-12-15
Release date:2019-12-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Maltotetraose-forming amylase from Pseudomonas saccharophila STB07
To Be Published

222415

건을2024-07-10부터공개중

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