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PDB: 721 件

8JMX
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The crystal structure of human aurka kinase domain in complex with AURKA-A2
分子名称: 5-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde, Aurora kinase A
著者Zhu, C.J, Zhang, Z.M.
登録日2023-06-05
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.95020175 Å)
主引用文献Multitarget inhibitors/probes that target LRRK2 and AURORA A kinases noncovalently and covalently.
Chem.Commun.(Camb.), 59, 2023
7ON1
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Cenp-A nucleosome in complex with Cenp-C
分子名称: BJ4_G0006610.mRNA.1.CDS.1, BJ4_G0007000.mRNA.1.CDS.1, DNA (123-MER), ...
著者Yan, K, Yang, J, Zhang, Z, Barford, D.
登録日2021-05-25
公開日2021-07-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cenp-A nucleosome in complex with Cenp-C
To Be Published
9AVL
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Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-04
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AVG
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Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-02
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AXF
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Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-06
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AYF
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Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-07
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9ASB
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BU of 9asb by Molmil
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-02-24
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
3OMH
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Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide
分子名称: Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22
著者Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
登録日2010-08-26
公開日2011-06-29
最終更新日2011-09-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate.
J.Biol.Chem., 286, 2011
7R5R
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Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7R5V
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Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
8GS3
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Cryo-EM structure of human Neuroligin 3
分子名称: Neuroligin-3
著者Zhang, H, Zhang, Z, Hou, M.
登録日2022-09-04
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Front Endocrinol, 13, 2022
8OVX
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Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus
分子名称: Inner kinetochore subunit AME1, Inner kinetochore subunit CTF19, Inner kinetochore subunit MCM21, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OVW
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Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA
分子名称: C0N3 DNA, Centromere-binding protein 1, Inner kinetochore subunit AME1, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OW0
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BU of 8ow0 by Molmil
Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome
分子名称: C0N3 DNA, Centromere-binding protein 1, Histone H2A.1, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8A5Y
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BU of 8a5y by Molmil
S. cerevisiae apo unphosphorylated APC/C.
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
8A61
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S. cerevisiae apo phosphorylated APC/C
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
8A3T
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S. cerevisiae APC/C-Cdh1 complex
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J.
登録日2022-06-09
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
6J3X
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The Structure of Maltooligosaccharide-forming Amylase from Pseudomonas saccharophila STB07 with Maltotriose
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glucan 1,4-alpha-maltotetraohydrolase, ...
著者Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H.
登録日2019-01-06
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Maltotetraose-forming amylase from Pseudomonas saccharophila STB07
To Be Published
8HPA
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Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ...
著者Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C.
登録日2022-12-12
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structure of DNA replication machinery from human monkeypox virus
To Be Published
3J2M
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The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the extended T4 tail
分子名称: Tail connector protein Gp15, Tail sheath protein Gp18
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-09
公開日2013-03-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
8WHA
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Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
著者Liu, Y, Zhang, Z, Du, J.
登録日2023-09-22
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WH5
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Structure of DDM1-nucleosome complex in the apo state
分子名称: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
著者Liu, Y, Zhang, Z, Du, J.
登録日2023-09-22
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WHB
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Structure of nucleosome core particle of Arabidopsis thaliana
分子名称: DNA (antisense strand), DNA (sense strand), Histone H2A.6, ...
著者Liu, Y, Zhang, Z, Du, J.
登録日2023-09-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WH9
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Structure of DDM1-nucleosome complex in ADP-BeFx state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
著者Liu, Y, Zhang, Z, Du, J.
登録日2023-09-22
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
6IYG
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The Structure of Maltooligosaccharide-forming Amylase from Pseudomonas saccharophila STB07 with Maltotetraose
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glucan 1,4-alpha-maltotetraohydrolase, ...
著者Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H.
登録日2018-12-15
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Maltotetraose-forming amylase from Pseudomonas saccharophila STB07
To Be Published

222415

件を2024-07-10に公開中

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