4C6R
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![BU of 4c6r by Molmil](/molmil-images/mine/4c6r) | Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPS4 | Descriptor: | DISEASE RESISTANCE PROTEIN RPS4 | Authors: | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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4AM6
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![BU of 4am6 by Molmil](/molmil-images/mine/4am6) | C-TERMINAL DOMAIN OF ACTIN-RELATED PROTEIN ARP8 FROM S. CEREVISIAE | Descriptor: | ACTIN-LIKE PROTEIN ARP8, SULFATE ION | Authors: | Wuerges, J, Saravanan, M, Bose, D, Cook, N.J, Zhang, X, Wigley, D.B. | Deposit date: | 2012-03-07 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Interactions between the Nucleosome Histone Core and Arp8 in the Ino80 Chromatin Remodeling Complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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4C6S
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![BU of 4c6s by Molmil](/molmil-images/mine/4c6s) | Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RRS1 | Descriptor: | GLYCEROL, PROBABLE WRKY TRANSCRIPTION FACTOR 52, SODIUM ION, ... | Authors: | Wan, L, Williams, S.J, Sohn, K.H, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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4AM7
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![BU of 4am7 by Molmil](/molmil-images/mine/4am7) | ADP-BOUND C-TERMINAL DOMAIN OF ACTIN-RELATED PROTEIN ARP8 FROM S. CEREVISIAE | Descriptor: | ACTIN-LIKE PROTEIN ARP8, ADENOSINE-5'-DIPHOSPHATE | Authors: | Wuerges, J, Saravanan, M, Bose, D, Cook, N.J, Zhang, X, Wigley, D.B. | Deposit date: | 2012-03-07 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Interactions between the Nucleosome Histone Core and Arp8 in the Ino80 Chromatin Remodeling Complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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6IRA
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![BU of 6ira by Molmil](/molmil-images/mine/6ira) | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 7.8 | Descriptor: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | Authors: | Zhang, J, Chang, S, Zhang, X, Zhu, S. | Deposit date: | 2018-11-12 | Release date: | 2019-01-16 | Last modified: | 2019-06-05 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018
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6IRG
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![BU of 6irg by Molmil](/molmil-images/mine/6irg) | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class II | Descriptor: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | Authors: | Zhang, J, Chang, S, Zhang, X, Zhu, S. | Deposit date: | 2018-11-12 | Release date: | 2019-01-16 | Last modified: | 2019-06-05 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018
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6D21
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![BU of 6d21 by Molmil](/molmil-images/mine/6d21) | |
4AU6
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![BU of 4au6 by Molmil](/molmil-images/mine/4au6) | Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles | Descriptor: | RNA-DEPENDENT RNA POLYMERASE | Authors: | Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C. | Deposit date: | 2012-05-14 | Release date: | 2012-06-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Location of the Dsrna-Dependent Polymerase, Vp1, in Rotavirus Particles. J.Mol.Biol., 425, 2013
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6D2Q
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![BU of 6d2q by Molmil](/molmil-images/mine/6d2q) | Crystal structure of the FERM domain of zebrafish FARP1 | Descriptor: | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | Authors: | Kuo, Y.C, Zhang, X. | Deposit date: | 2018-04-13 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
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4C6T
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![BU of 4c6t by Molmil](/molmil-images/mine/4c6t) | Crystal structure of the RPS4 and RRS1 TIR domain heterodimer | Descriptor: | DISEASE RESISTANCE PROTEIN RPS4, MALONIC ACID, PROBABLE WRKY TRANSCRIPTION FACTOR 52 | Authors: | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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4DFF
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![BU of 4dff by Molmil](/molmil-images/mine/4dff) | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia | Descriptor: | 8,9-dimethoxy-1-(1,3-thiazol-5-yl)-5,6-dihydroimidazo[5,1-a]isoquinoline, MAGNESIUM ION, ZINC ION, ... | Authors: | Ho, G.D, Seganish, W.M, Bercovici, A, Tulshian, D, Greenlee, W.J, Van Rijn, R, Hruza, A, Xiao, L, Rindgen, D, Mullins, D, Guzzi, M, Zhang, X, Bleichardt, C, Hodgson, R. | Deposit date: | 2012-01-23 | Release date: | 2012-03-14 | Last modified: | 2012-04-04 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg.Med.Chem.Lett., 22, 2012
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4DHI
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![BU of 4dhi by Molmil](/molmil-images/mine/4dhi) | Structure of C. elegans OTUB1 bound to human UBC13 | Descriptor: | Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N | Authors: | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | Deposit date: | 2012-01-27 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
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3KH8
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![BU of 3kh8 by Molmil](/molmil-images/mine/3kh8) | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici | Descriptor: | MaoC-like dehydratase | Authors: | Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. | Deposit date: | 2009-10-30 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici To be Published
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6IFL
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![BU of 6ifl by Molmil](/molmil-images/mine/6ifl) | Cryo-EM structure of type III-A Csm-NTR complex | Descriptor: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-20 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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2LIT
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![BU of 2lit by Molmil](/molmil-images/mine/2lit) | NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states | Descriptor: | Cytochrome c iso-1, HEME C | Authors: | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | Deposit date: | 2011-08-31 | Release date: | 2011-12-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States. Plos One, 6, 2011
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4TOR
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![BU of 4tor by Molmil](/molmil-images/mine/4tor) | Crystal structure of Tankyrase 1 with IWR-8 | Descriptor: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | Authors: | Chen, H, Zhang, X, Lum, L, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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2LIR
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![BU of 2lir by Molmil](/molmil-images/mine/2lir) | NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states | Descriptor: | Cytochrome c iso-1, HEME C | Authors: | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | Deposit date: | 2011-08-31 | Release date: | 2011-12-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States. Plos One, 6, 2011
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1RKU
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![BU of 1rku by Molmil](/molmil-images/mine/1rku) | Crystal Structure of ThrH gene product of Pseudomonas Aeruginosa | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, homoserine kinase | Authors: | Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H. | Deposit date: | 2003-11-23 | Release date: | 2004-03-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity. J.Biol.Chem., 279, 2004
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4TOS
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![BU of 4tos by Molmil](/molmil-images/mine/4tos) | Crystal structure of Tankyrase 1 with 355 | Descriptor: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | Authors: | Chen, H, Zhang, X, Lum, l, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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1BR0
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![BU of 1br0 by Molmil](/molmil-images/mine/1br0) | THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A | Descriptor: | PROTEIN (SYNTAXIN 1-A) | Authors: | Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J. | Deposit date: | 1998-08-25 | Release date: | 1998-09-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A. Cell(Cambridge,Mass.), 94, 1998
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8EQB
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![BU of 8eqb by Molmil](/molmil-images/mine/8eqb) | FAM46C/BCCIPalpha/Nanobody complex | Descriptor: | Isoform 2 of BRCA2 and CDKN1A-interacting protein, Synthetic nanobody 1, Terminal nucleotidyltransferase 5C | Authors: | Liu, S, Chen, H, Yin, Y, Bai, X, Zhang, X. | Deposit date: | 2022-10-07 | Release date: | 2023-03-15 | Last modified: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Inhibition of FAM46/TENT5 activity by BCCIP alpha adopting a unique fold. Sci Adv, 9, 2023
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190D
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![BU of 190d by Molmil](/molmil-images/mine/190d) | |
1BM6
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![BU of 1bm6 by Molmil](/molmil-images/mine/1bm6) | SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 COMPLEXED TO A POTENT NON-PEPTIDIC INHIBITOR, NMR, 20 STRUCTURES | Descriptor: | 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ... | Authors: | Li, Y, Zhang, X, Melton, R, Ganu, V, Gonnella, N.C. | Deposit date: | 1998-07-29 | Release date: | 1999-07-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor. Biochemistry, 37, 1998
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1C76
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![BU of 1c76 by Molmil](/molmil-images/mine/1c76) | STAPHYLOKINASE (SAK) MONOMER | Descriptor: | STAPHYLOKINASE | Authors: | Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y. | Deposit date: | 2000-02-01 | Release date: | 2000-08-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity To be published
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6S8F
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![BU of 6s8f by Molmil](/molmil-images/mine/6s8f) | Structure of nucleotide-bound Tel1/ATM | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | Authors: | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | Deposit date: | 2019-07-09 | Release date: | 2019-10-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28, 2020
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