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PDB: 1139 results

7QV9
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BU of 7qv9 by Molmil
CryoEM structure of bacterial transcription intermediate complex mediated by activator PspF
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, DNA-directed RNA polymerase subunit alpha, ...
Authors:Ye, F.Z, Zhang, X.D.
Deposit date:2022-01-20
Release date:2022-11-09
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanisms of DNA opening revealed in AAA+ transcription complex structures.
Sci Adv, 8, 2022
7QWP
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BU of 7qwp by Molmil
CryoEM structure of bacterial transcription close complex (RPc)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ye, F.Z, Zhang, X.D.
Deposit date:2022-01-25
Release date:2022-11-09
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanisms of DNA opening revealed in AAA+ transcription complex structures.
Sci Adv, 8, 2022
4QWQ
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BU of 4qwq by Molmil
Crystal structure of the DNA-binding domain of the response regulator SaeR from Staphylococcus aureus
Descriptor: Response regulator SaeR
Authors:Fan, X, Zhu, Y, Zhang, X, Teng, M, Li, X.
Deposit date:2014-07-17
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structure of the DNA-binding domain of the response regulator SaeR from Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 71, 2015
6O0W
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BU of 6o0w by Molmil
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-2'-5'-DIPHOSPHATE, TIR-NB-LRR type resistance protein RUN1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0V
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BU of 6o0v by Molmil
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 2
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
4TOR
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BU of 4tor by Molmil
Crystal structure of Tankyrase 1 with IWR-8
Descriptor: 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ...
Authors:Chen, H, Zhang, X, Lum, L, Chen, C.
Deposit date:2014-06-06
Release date:2015-05-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
6O1B
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BU of 6o1b by Molmil
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Sterile alpha and TIR motif-containing protein 1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-18
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0U
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BU of 6o0u by Molmil
Crystal structure of the TIR domain H685A mutant from human SARM1
Descriptor: Sterile alpha and TIR motif-containing protein 1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0Q
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BU of 6o0q by Molmil
Crystal structure of the TIR domain from human SARM1 in complex with ribose
Descriptor: CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1, beta-D-ribofuranose
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
1BML
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BU of 1bml by Molmil
COMPLEX OF THE CATALYTIC DOMAIN OF HUMAN PLASMIN AND STREPTOKINASE
Descriptor: PLASMIN, STREPTOKINASE
Authors:Wang, X, Zhang, X.C.
Deposit date:1999-05-25
Release date:1999-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the catalytic domain of human plasmin complexed with streptokinase.
Science, 281, 1998
8EQB
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BU of 8eqb by Molmil
FAM46C/BCCIPalpha/Nanobody complex
Descriptor: Isoform 2 of BRCA2 and CDKN1A-interacting protein, Synthetic nanobody 1, Terminal nucleotidyltransferase 5C
Authors:Liu, S, Chen, H, Yin, Y, Bai, X, Zhang, X.
Deposit date:2022-10-07
Release date:2023-03-15
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Inhibition of FAM46/TENT5 activity by BCCIP alpha adopting a unique fold.
Sci Adv, 9, 2023
8EXE
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BU of 8exe by Molmil
Crystal structure of human FAM46A-BCCIPa complex at 3.5 angstrom resolution
Descriptor: Isoform 2 of BRCA2 and CDKN1A-interacting protein, Terminal nucleotidyltransferase 5A
Authors:Liu, S, Zhang, X.
Deposit date:2022-10-25
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of FAM46/TENT5 activity by BCCIP alpha adopting a unique fold.
Sci Adv, 9, 2023
190D
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BU of 190d by Molmil
Crystal structure of a four-stranded intercalated DNA: d(C4)
Descriptor: DNA (5'-D(*CP*CP*CP*C)-3')
Authors:Chen, L, Cai, L, Zhang, X, Rich, A.
Deposit date:1994-09-02
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a four-stranded intercalated DNA: d(C4).
Biochemistry, 33, 1994
5ADY
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BU of 5ady by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with HflX
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
Authors:Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
6R9G
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BU of 6r9g by Molmil
Structural basis of transcription inhibition by the DNA mimic Ocr protein of bacteriophage T7
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ye, F.Z, Zhang, X.D.
Deposit date:2019-04-03
Release date:2020-02-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7.
Elife, 9, 2020
1D59
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BU of 1d59 by Molmil
CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3')
Authors:Kang, C, Zhang, X, Ratliff, R, Moyzis, R, Rich, A.
Deposit date:1992-02-25
Release date:1993-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of four-stranded Oxytricha telomeric DNA.
Nature, 356, 1992
6VUA
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BU of 6vua by Molmil
X-ray structure of human CD38 catalytic domain with 2'-Cl-araNAD+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, DI(HYDROXYETHYL)ETHER, ...
Authors:Dai, Z, Zhang, X.N, Nasertorabi, F, Han, G.W, Stevens, R.C, Zhang, Y.
Deposit date:2020-02-14
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases.
Sci Adv, 6, 2020
1AWP
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BU of 1awp by Molmil
RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5
Descriptor: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wang, X, Zhang, X.
Deposit date:1997-10-03
Release date:1998-10-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The reduction potential of cytochrome b5 is modulated by its exposed heme edge.
Biochemistry, 37, 1998
4R2P
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BU of 4r2p by Molmil
Wilms Tumor Protein (WT1) zinc fingers in complex with hydroxymethylated DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5HC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5HC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ...
Authors:Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X.
Deposit date:2014-08-12
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.788 Å)
Cite:Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
4R2A
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BU of 4r2a by Molmil
Egr1/Zif268 zinc fingers in complex with methylated DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ...
Authors:Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X.
Deposit date:2014-08-11
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.591 Å)
Cite:Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
4R2D
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BU of 4r2d by Molmil
Egr1/Zif268 zinc fingers in complex with formylated DNA
Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5FC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), Early growth response protein 1, ...
Authors:Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X.
Deposit date:2014-08-11
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.088 Å)
Cite:Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
6Z3A
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BU of 6z3a by Molmil
Mec1-Ddc2 (wild-type) in complex with AMP-PNP
Descriptor: DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ...
Authors:Yates, L.A, Zhang, X.
Deposit date:2020-05-19
Release date:2020-11-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
173L
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BU of 173l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Xiong, X.-P, Zhang, X.-J, Sun, D, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
6Z2W
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BU of 6z2w by Molmil
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP
Descriptor: DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Yates, L.A, Zhang, X.
Deposit date:2020-05-18
Release date:2020-11-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
4R2S
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BU of 4r2s by Molmil
Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ...
Authors:Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X.
Deposit date:2014-08-12
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014

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