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PDB: 1134 results

4O9F
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crystal structure of horse MAVS card domain mutant R64C
Descriptor: mitochondrial antiviral signaling protein (MAVS)
Authors:Zhang, X, He, X.
Deposit date:2014-01-02
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:Structural basis for the prion-like MAVS filaments in antiviral innate immunity.
Elife, 3, 2014
4DXW
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BU of 4dxw by Molmil
Crystal structure of NavRh, a voltage-gated sodium channel
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
Authors:Zhang, X, Ren, W.L, Yan, C.Y, Wang, J.W, Yan, N.
Deposit date:2012-02-28
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
Nature, 486, 2012
6LRM
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BU of 6lrm by Molmil
Crystal structure of PDE4D catalytic domain in complex with arctigenin
Descriptor: 1,2-ETHANEDIOL, Arctigenin, MAGNESIUM ION, ...
Authors:Zhang, X.L, Li, M.J, Xu, Y.C.
Deposit date:2020-01-16
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation.
J Adv Res, 33, 2021
7YSK
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BU of 7ysk by Molmil
Crystal structure of D-Cysteine desulfhydrase from Pectobacterium atrosepticum
Descriptor: D-Cysteine desulfhydrase
Authors:Zhang, X, Wang, L, Xu, X, Xing, X, Zhou, J.
Deposit date:2022-08-12
Release date:2022-12-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum
Tetrahedron, 2022
4O9L
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crystal structure of horse MAVS card domain mutant E26R
Descriptor: mitochondrial antiviral signaling protein (MAVS)
Authors:Zhang, X, He, X.
Deposit date:2014-01-02
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:Structural basis for the prion-like MAVS filaments in antiviral innate immunity.
Elife, 3, 2014
2B5X
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Solution Structure of a Thioredoxin-like Protein in the Reduced Form
Descriptor: YkuV protein
Authors:Zhang, X, Xia, B, Jin, C.
Deposit date:2005-09-29
Release date:2006-01-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity
J.Biol.Chem., 281, 2006
5ZH0
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BU of 5zh0 by Molmil
Crystal Structures of Endo-beta-1,4-xylanase II
Descriptor: Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION
Authors:Zhang, X, Wan, Q, Li, Z.
Deposit date:2018-03-10
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal Structures of Endo-beta-1,4-xylanase II
To be published
3F4M
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BU of 3f4m by Molmil
Crystal structure of TIPE2
Descriptor: CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2
Authors:Zhang, X, Wang, J, Shi, Y.
Deposit date:2008-11-01
Release date:2009-03-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Crystal structure of TIPE2 provides insights into immune homeostasis
Nat.Struct.Mol.Biol., 16, 2009
2B5Y
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Solution Structure of a Thioredoxin-like Protein in the Oxidized Form
Descriptor: YkuV protein
Authors:Zhang, X, Xia, B, Jin, C.
Deposit date:2005-09-29
Release date:2006-01-17
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:The bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity
J.Biol.Chem., 281, 2006
6K5L
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BU of 6k5l by Molmil
The crystal structure of isocitrate dehydrogenase kinase/phosphatase wtih two Mn2+ from E. coli
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
Authors:Zhang, X, Lei, Z, Zheng, J, Jia, Z.
Deposit date:2019-05-29
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Characterization of metal binding of bifunctional kinase/phosphatase AceK and implication in activity modulation.
Sci Rep, 9, 2019
2RFE
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BU of 2rfe by Molmil
Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
Authors:Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
Deposit date:2007-09-28
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
4N6F
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BU of 4n6f by Molmil
Crystal structure of Amycolatopsis orientalis BexX complexed with G6P
Descriptor: CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase
Authors:Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E.
Deposit date:2013-10-11
Release date:2014-05-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
2RFD
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Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor, SULFATE ION
Authors:Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
Deposit date:2007-09-28
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
2RF9
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BU of 2rf9 by Molmil
Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
Authors:Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
Deposit date:2007-09-28
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
2GS6
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BU of 2gs6 by Molmil
Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate
Descriptor: CHLORIDE ION, Epidermal growth factor receptor, Peptide, ...
Authors:Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
Deposit date:2006-04-25
Release date:2006-06-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Cell(Cambridge,Mass.), 125, 2006
4Q2M
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BU of 4q2m by Molmil
Structure of the E. coli YajR Transporter YAM Domain Combined Iodine
Descriptor: ACETIC ACID, CADMIUM ION, IODIDE ION, ...
Authors:Zhang, X.C.
Deposit date:2014-04-09
Release date:2014-07-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.489 Å)
Cite:Atomic resolution structure of the E. coli YajR transporter YAM domain.
Biochem.Biophys.Res.Commun., 450, 2014
2GS2
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BU of 2gs2 by Molmil
Crystal Structure of the active EGFR kinase domain
Descriptor: Epidermal growth factor receptor
Authors:Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
Deposit date:2006-04-25
Release date:2006-06-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Cell(Cambridge,Mass.), 125, 2006
2MQ0
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BU of 2mq0 by Molmil
NMR structure of the c3 domain of human cardiac myosin binding protein-c
Descriptor: Myosin-binding protein C, cardiac-type
Authors:Zhang, X, De, S, Mcintosh, L.P, Paetzel, M.
Deposit date:2014-06-10
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.
Biochemistry, 53, 2014
2MQ3
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BU of 2mq3 by Molmil
NMR structure of the c3 domain of human cardiac myosin binding protein-c with a hypertrophic cardiomyopathy-related mutation R502W.
Descriptor: Myosin-binding protein C, cardiac-type
Authors:Zhang, X, De, S, Mcintosh, L.P, Paetzel, M.
Deposit date:2014-06-12
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.
Biochemistry, 53, 2014
7CBQ
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BU of 7cbq by Molmil
Crystal structure of PDE4D catalytic domain in complex with Apremilast
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide, ...
Authors:Zhang, X.L, Xu, Y.C.
Deposit date:2020-06-13
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment.
Eur.J.Med.Chem., 211, 2021
4OA7
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BU of 4oa7 by Molmil
Crystal structure of Tankyrase1 in complex with IWR1
Descriptor: 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION
Authors:Zhang, X, He, H.
Deposit date:2014-01-03
Release date:2015-01-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
7CBJ
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BU of 7cbj by Molmil
Crystal structure of PDE4D catalytic domain in complex with compound 36
Descriptor: (1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Zhang, X.L, Xu, Y.C.
Deposit date:2020-06-12
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment.
Eur.J.Med.Chem., 211, 2021
7YOB
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BU of 7yob by Molmil
Crystal structure of Aldehyde dehydrogenase 1A1 from mouse
Descriptor: Aldehyde dehydrogenase 1A1
Authors:Zhang, X.Y, Ouyang, Z.Q.
Deposit date:2022-08-01
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal structure of aldehyde dehydrogenase 1A1 from mouse.
Biochem.Biophys.Res.Commun., 628, 2022
7YSL
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BU of 7ysl by Molmil
Crystal structure of D-Cysteine desulfhydrase with a trapped PLP-pyruvate geminal diamine
Descriptor: 1,2-ETHANEDIOL, D-Cysteine desulfhydrase, FORMIC ACID
Authors:Zhang, X, Wang, L, Xu, X, Xing, X, Zhou, J.
Deposit date:2022-08-12
Release date:2022-12-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum
Tetrahedron, 2022
189L
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BU of 189l by Molmil
ENHANCEMENT OF PROTEIN STABILITY BY THE COMBINATION OF POINT MUTATIONS IN T4 LYSOZYME IS ADDITIVE
Descriptor: T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-05-09
Release date:1995-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive.
Protein Eng., 8, 1995

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