4GJG
Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.
Summary for 4GJG
Entry DOI | 10.2210/pdb4gjg/pdb |
Related | 1AP4 1J1D 1MXL 1SPY 3SD6 3SWB 4GJE 4GJF |
Descriptor | Troponin C, slow skeletal and cardiac muscles, CADMIUM ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | helix-loop-helix ef-hand motif, contractile protein, calcium sensor, cadmium binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 11214.60 |
Authors | Zhang, X.,Paetzel, M. (deposition date: 2012-08-09, release date: 2013-02-06, Last modification date: 2024-02-28) |
Primary citation | Zhang, X.L.,Tibbits, G.F.,Paetzel, M. The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination. Acta Crystallogr.,Sect.D, 69:722-734, 2013 Cited by PubMed: 23633581DOI: 10.1107/S0907444913001182 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report