4GJG
Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Troponin C, slow skeletal and cardiac muscles | polymer | 89 | 10156.4 | 1 | UniProt (P63316) Pfam (PF13833) | Homo sapiens (human) | TN-C |
| 2 | B, C, D, E, F... (A) | CADMIUM ION | non-polymer | 112.4 | 7 | Chemie (CD) | |||
| 3 | I, J, K (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | L (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | M (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | N (A) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 1 - 89 (UniProt: P63316)
| PDB | External Database | Details |
|---|---|---|
| Asn 2 | Asp 2 | engineered mutation |
| Ile 28 | Val 28 | engineered mutation |
| Gln 29 | Leu 29 | engineered mutation |
| Asp 30 | Gly 30 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10156.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1058.2 | |
| All* | Total formula weight | 11214.6 |
