1RKV
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![BU of 1rkv by Molmil](/molmil-images/mine/1rkv) | Structure of Phosphate complex of ThrH from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H. | Deposit date: | 2003-11-23 | Release date: | 2004-03-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity. J.Biol.Chem., 279, 2004
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5CB3
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![BU of 5cb3 by Molmil](/molmil-images/mine/5cb3) | Structural Insights into the Mechanism of Escherichia coli Ymdb | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase | Authors: | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | Deposit date: | 2015-06-30 | Release date: | 2015-11-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase J.Struct.Biol., 192, 2015
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4M9V
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![BU of 4m9v by Molmil](/molmil-images/mine/4m9v) | Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X. | Deposit date: | 2013-08-15 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (0.969 Å) | Cite: | DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom. Biochemistry, 52, 2013
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1VAZ
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![BU of 1vaz by Molmil](/molmil-images/mine/1vaz) | Solution structures of the p47 SEP domain | Descriptor: | NSFL1 cofactor p47 | Authors: | Yuan, X, Simpson, P, Mckeown, C, Kondo, H, Uchiyama, K, Wallis, R, Dreveny, I, Keetch, C, Zhang, X, Robinson, C, Freemont, P, Matthews, S. | Deposit date: | 2004-02-20 | Release date: | 2004-04-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97. Embo J., 23, 2004
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5CF3
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![BU of 5cf3 by Molmil](/molmil-images/mine/5cf3) | Crystal structures of Bbp from Staphylococcus aureus | Descriptor: | Bone sialoprotein-binding protein, CALCIUM ION | Authors: | Yu, Y, Zhang, X.Y, Gu, J.K. | Deposit date: | 2015-07-08 | Release date: | 2015-09-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.031 Å) | Cite: | Crystal structures of Bbp from Staphylococcus aureus reveal the ligand binding mechanism with Fibrinogen alpha Protein Cell, 6, 2015
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5CFA
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1X79
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![BU of 1x79 by Molmil](/molmil-images/mine/1x79) | Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADP-ribosylation factor binding protein GGA1, Rab GTPase binding effector protein 1, ... | Authors: | Zhu, G, Zhang, X.C. | Deposit date: | 2004-08-13 | Release date: | 2004-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5. EMBO J., 23, 2004
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4C6T
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![BU of 4c6t by Molmil](/molmil-images/mine/4c6t) | Crystal structure of the RPS4 and RRS1 TIR domain heterodimer | Descriptor: | DISEASE RESISTANCE PROTEIN RPS4, MALONIC ACID, PROBABLE WRKY TRANSCRIPTION FACTOR 52 | Authors: | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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4DFF
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![BU of 4dff by Molmil](/molmil-images/mine/4dff) | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia | Descriptor: | 8,9-dimethoxy-1-(1,3-thiazol-5-yl)-5,6-dihydroimidazo[5,1-a]isoquinoline, MAGNESIUM ION, ZINC ION, ... | Authors: | Ho, G.D, Seganish, W.M, Bercovici, A, Tulshian, D, Greenlee, W.J, Van Rijn, R, Hruza, A, Xiao, L, Rindgen, D, Mullins, D, Guzzi, M, Zhang, X, Bleichardt, C, Hodgson, R. | Deposit date: | 2012-01-23 | Release date: | 2012-03-14 | Last modified: | 2012-04-04 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg.Med.Chem.Lett., 22, 2012
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4DHI
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![BU of 4dhi by Molmil](/molmil-images/mine/4dhi) | Structure of C. elegans OTUB1 bound to human UBC13 | Descriptor: | Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N | Authors: | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | Deposit date: | 2012-01-27 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
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1DP4
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![BU of 1dp4 by Molmil](/molmil-images/mine/1dp4) | DIMERIZED HORMONE BINDING DOMAIN OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATRIAL NATRIURETIC PEPTIDE RECEPTOR A, ... | Authors: | van den Akker, F, Zhang, X, Miyagi, M, Huo, X, Misono, K.S, Yee, V.C. | Deposit date: | 1999-12-23 | Release date: | 2000-07-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor. Nature, 406, 2000
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1U2Z
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![BU of 1u2z by Molmil](/molmil-images/mine/1u2z) | Crystal structure of histone K79 methyltransferase Dot1p from yeast | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. | Deposit date: | 2004-07-20 | Release date: | 2004-09-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase J.Biol.Chem., 279, 2004
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1RHP
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2K9X
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![BU of 2k9x by Molmil](/molmil-images/mine/2k9x) | Solution structure of Urm1 from Trypanosoma brucei | Descriptor: | Uncharacterized protein | Authors: | Zhang, W, Zhang, J, Xu, C, Wang, T, Zhang, X, Tu, X. | Deposit date: | 2008-10-27 | Release date: | 2009-03-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of Urm1 from Trypanosoma brucei Proteins, 75, 2009
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2OBR
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![BU of 2obr by Molmil](/molmil-images/mine/2obr) | Crystal Structures of P Domain of Norovirus VA387 | Descriptor: | Capsid protein | Authors: | Cao, S, Lou, Z, Jiang, X, Zhang, X.C, Li, X, Rao, Z. | Deposit date: | 2006-12-20 | Release date: | 2007-04-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the recognition of blood group trisaccharides by norovirus. J.Virol., 81, 2007
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8WOR
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![BU of 8wor by Molmil](/molmil-images/mine/8wor) | Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | Deposit date: | 2023-10-07 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1. Cell Discov, 10, 2024
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8WOQ
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![BU of 8woq by Molmil](/molmil-images/mine/8woq) | Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | Deposit date: | 2023-10-07 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1. Cell Discov, 10, 2024
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1F4H
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![BU of 1f4h by Molmil](/molmil-images/mine/1f4h) | E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | Deposit date: | 2000-06-07 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
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1F4A
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![BU of 1f4a by Molmil](/molmil-images/mine/1f4a) | E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | Deposit date: | 2000-06-07 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
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3F8I
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![BU of 3f8i by Molmil](/molmil-images/mine/3f8i) | Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group P21 | Descriptor: | 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1 | Authors: | Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X. | Deposit date: | 2008-11-12 | Release date: | 2009-01-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications. Epigenetics, 4, 2009
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1F6W
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3O5X
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![BU of 3o5x by Molmil](/molmil-images/mine/3o5x) | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | Descriptor: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | Deposit date: | 2010-07-28 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). J.Med.Chem., 53, 2010
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2L6K
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![BU of 2l6k by Molmil](/molmil-images/mine/2l6k) | Solution Structure of a Nonphosphorylated Peptide Recognizing Domain | Descriptor: | Tensin-like C1 domain-containing phosphatase | Authors: | Dai, K, Liao, S, Zhang, J, Zhang, X, Tu, X. | Deposit date: | 2010-11-22 | Release date: | 2011-10-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of Tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1 Plos One, 6, 2011
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8GWA
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![BU of 8gwa by Molmil](/molmil-images/mine/8gwa) | Structure of the intact photosynthetic light-harvesting antenna-reaction center complex from a green sulfur bacterium | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E,19E)-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaenyl]-1,3,4-trimethyl-benzene, ... | Authors: | Chen, J.H, Zhang, X. | Deposit date: | 2022-09-16 | Release date: | 2022-11-23 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-electron microscopy structure of the intact photosynthetic light-harvesting antenna-reaction center complex from a green sulfur bacterium. J Integr Plant Biol, 65, 2023
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3KV9
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![BU of 3kv9 by Molmil](/molmil-images/mine/3kv9) | Structure of KIAA1718 Jumonji domain | Descriptor: | FE (II) ION, JmjC domain-containing histone demethylation protein 1D, OXYGEN MOLECULE | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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