8WOR

Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH

Summary for 8WOR

• Entry DOI: 10.2210/pdb8wor/pdb
• EMDB information: 37695 37696
• Descriptor: SID1 transmembrane family member 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (9 entities in total)
• Functional Keywords: ceramidase, putative rna and cholesterol transport protein, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 209399.94

Authors

Liu, W.,Tang, M.,Wang, J.,Zhang, X.,Wu, S.,Ru, H. (deposition date: 2023-10-07, release date: 2024-03-20, Last modification date: 2025-07-02)

• Primary citation: Liu, W.,Tang, M.,Wang, J.,Wang, F.,Song, G.,Zhang, X.,Wu, S.,Ru, H.; Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1.; Cell Discov, 10:21-21, 2024; PubMed: 38378654; DOI: 10.1038/s41421-024-00647-2

Experimental method

ELECTRON MICROSCOPY (2.66 Å)