8WOR
Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | SID1 transmembrane family member 1 | polymer | 881 | 99695.2 | 2 | UniProt (Q9NXL6) Pfam (PF13965) In PDB | Homo sapiens (human) | |
| 2 | C, D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | B, A | CHOLESTEROL | non-polymer | 386.7 | 15 | Chemie (CLR) | |||
| 7 | B, A | OLEIC ACID | non-polymer | 282.5 | 2 | Chemie (OLA) | |||
| 8 | A, B | OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE | non-polymer | 425.7 | 2 | Chemie (SPL) | |||
| 9 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 832 (UniProt: Q9NXL6)
| PDB | External Database | Details |
|---|---|---|
| Ser 833 | - | expression tag |
| Arg 834 | - | expression tag |
| Glu 835 | - | expression tag |
| Asn 836 | - | expression tag |
| Leu 837 | - | expression tag |
| Tyr 838 | - | expression tag |
| Phe 839 | - | expression tag |
| Gln 840 | - | expression tag |
| Gly 841 | - | expression tag |
| Ser 842 | - | expression tag |
| Gly 843 | - | expression tag |
| Trp 844 | - | expression tag |
| Ser 845 | - | expression tag |
| His 846 | - | expression tag |
| Pro 847 | - | expression tag |
| Gln 848 | - | expression tag |
| Phe 849 | - | expression tag |
| Glu 850 | - | expression tag |
| Lys 851 | - | expression tag |
| Gly 852 | - | expression tag |
| Gly 853 | - | expression tag |
| Gly 854 | - | expression tag |
| Ser 855 | - | expression tag |
| Gly 856 | - | expression tag |
| Gly 857 | - | expression tag |
| Gly 858 | - | expression tag |
| Ser 859 | - | expression tag |
| Gly 860 | - | expression tag |
| Gly 861 | - | expression tag |
| Ser 862 | - | expression tag |
| Ala 863 | - | expression tag |
| Trp 864 | - | expression tag |
| Ser 865 | - | expression tag |
| His 866 | - | expression tag |
| Pro 867 | - | expression tag |
| Gln 868 | - | expression tag |
| Phe 869 | - | expression tag |
| Glu 870 | - | expression tag |
| Lys 871 | - | expression tag |
| Gly 872 | - | expression tag |
| Ser 873 | - | expression tag |
| Asp 874 | - | expression tag |
| Tyr 875 | - | expression tag |
| Lys 876 | - | expression tag |
| Asp 877 | - | expression tag |
| Asp 878 | - | expression tag |
| Asp 879 | - | expression tag |
| Asp 880 | - | expression tag |
| Lys 881 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 199390.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 8311.9 | |
| All* | Total formula weight | 209399.9 |
