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PDB: 80 件
4DW2
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BU of 4dw2 by Molmil
The crystal structure of uPA in complex with the Fab fragment of mAb-112
分子名称: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
登録日2012-02-24
公開日2013-01-16
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
4DVA
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BU of 4dva by Molmil
The crystal structure of human urokinase-type plasminogen activator catalytic domain
分子名称: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
登録日2012-02-23
公開日2013-01-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
4H42
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BU of 4h42 by Molmil
Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, N-[(2-amino-1,3-benzothiazol-6-yl)carbonyl]glycine, Urokinase-type plasminogen activator
著者Yu, H.-Y, Gao, D, Zhang, X, Jiang, L.-G, Hong, Z.-B, Yuan, C, Fang, X, Wang, J.-D, Huang, M.-D.
登録日2012-09-14
公開日2013-10-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA
CHIN.J.STRUCT.CHEM., 32, 2013
3KHV
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BU of 3khv by Molmil
Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
分子名称: SULFATE ION, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator, ...
著者Jiang, L.-G, Zhao, G.-X, Bian, X.-B, Yuan, C, Huang, Z.-X, Huang, M.-D.
登録日2009-10-30
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
CHIN.J.STRUCT.CHEM., 28, 2009
3KID
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BU of 3kid by Molmil
The Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
分子名称: Urokinase-type plasminogen activator, ethyl 2-amino-1,3-benzothiazole-6-carboxylate
著者Jiang, L.-G, Yu, H.Y, Yuan, C, Wang, J.D, Chen, L.Q, Meehan, E.J, Huang, Z.-X, Huang, M.-D.
登録日2009-11-01
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
CHIN.J.STRUCT.CHEM., 28, 2009
3KGP
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BU of 3kgp by Molmil
Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
分子名称: 4-(aminomethyl)benzoic acid, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.-G, Zhao, G.-X, Bian, X.-B, Yuan, C, Huang, Z.-X, Huang, M.-D.
登録日2009-10-29
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
CHIN.J.STRUCT.CHEM., 28, 2009
3MHW
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BU of 3mhw by Molmil
The complex crystal Structure of Urokianse and 2-Aminobenzothiazole
分子名称: 1,3-benzothiazol-2-amine, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.-G, Yuan, C, Chen, L.-Q, Huang, M.-D.
登録日2010-04-09
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
CHIN.J.STRUCT.CHEM., 28, 2009
3M61
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BU of 3m61 by Molmil
Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
分子名称: Urokinase-type plasminogen activator, upain-1 W3A
著者Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M.
登録日2010-03-15
公開日2010-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
TO BE PUBLISHED
3MWI
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BU of 3mwi by Molmil
The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine
分子名称: 5-nitro-1H-indole-2-carboximidamide, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.G, Yu, H.Y, Yuan, C, Huang, Z.X, Huang, M.D.
登録日2010-05-06
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine
To be Published
6BV7
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BU of 6bv7 by Molmil
NMR structure of Sodium/Calcium Exchanger 1 (NCX1) Two-helix Bundle (THB) domain
分子名称: Sodium/calcium exchanger 1
著者Yuan, J, Yuan, C, Bruschweiler, R.
登録日2017-12-12
公開日2018-06-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Intracellular Loop of the Na+/Ca2+Exchanger Contains an "Awareness Ribbon"-Shaped Two-Helix Bundle Domain.
Biochemistry, 57, 2018
2JXJ
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BU of 2jxj by Molmil
NMR structure of the ARID domain from the histone H3K4 demethylase RBP2
分子名称: Histone demethylase JARID1A
著者Tu, S, Yuan, C, Tsai, M.
登録日2007-11-20
公開日2008-09-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif
Nat.Struct.Mol.Biol., 15, 2008
2KHZ
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BU of 2khz by Molmil
Solution Structure of RCL
分子名称: c-Myc-responsive protein Rcl
著者Doddapaneni, K, Mahler, B, Yuan, C, Wu, Z.
登録日2009-04-15
公開日2009-10-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of RCL, a novel 2'-deoxyribonucleoside 5'-monophosphate N-glycosidase
J.Mol.Biol., 394, 2009
2NWN
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BU of 2nwn by Molmil
New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1
分子名称: Plasminogen activator, urokinase, upain-1
著者Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC)
登録日2006-11-16
公開日2007-10-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
2O8U
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BU of 2o8u by Molmil
Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
分子名称: BENZAMIDINE, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
著者Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M.
登録日2006-12-12
公開日2007-12-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
To be Published
3U73
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BU of 3u73 by Molmil
Crystal structure of stabilized human uPAR mutant in complex with ATF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
著者Huang, M.D, Xu, X, Yuan, C.
登録日2011-10-13
公開日2012-04-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
3U74
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BU of 3u74 by Molmil
Crystal structure of stabilized human uPAR mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor
著者Huang, M.D, Xu, X, Yuan, C.
登録日2011-10-13
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
5YIP
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BU of 5yip by Molmil
Crystal Structure of AnkG LIR/GABARAPL1 complex
分子名称: Ankyrin-3, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1
著者Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M.
登録日2017-10-06
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
8Y7F
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BU of 8y7f by Molmil
Crystal structure of CARF domain-truncated Csx1-Crn2 from Marinitoga sp.
分子名称: CRISPR-associated protein
著者Zhang, D, Yuan, C, Lin, Z.
登録日2024-02-04
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Nucleic Acids Res., 2024
8Y7G
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BU of 8y7g by Molmil
Crystal structure of the Marinitoga sp. Csx1-Crn2 H495A mutant in complex with cyclic-tetraadenylate (cA4)
分子名称: ACETATE ION, CRISPR-associated protein, RNA (5'-R(P*AP*A)-3'), ...
著者Zhang, D, Yuan, C, Lin, Z.
登録日2024-02-04
公開日2024-07-17
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Nucleic Acids Res., 2024
8Y6Z
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BU of 8y6z by Molmil
Crystal structure of the Marinitoga sp. Csx1-Crn2 fusion ribonuclease of type III CRISPR
分子名称: CRISPR-associated protein
著者Zhang, D, Yuan, C.
登録日2024-02-03
公開日2024-07-17
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Nucleic Acids Res., 2024
8Y75
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BU of 8y75 by Molmil
Crystal structure of the CARF-HTH domain of Csx1-Crn2 from Marinitoga sp.
分子名称: CRISPR-associated protein
著者Zhang, D, Yuan, C, Lin, Z.
登録日2024-02-03
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Nucleic Acids Res., 2024
6JRG
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BU of 6jrg by Molmil
Crystal structure of ZmMoc1 H253A mutant in complex with Holliday junction
分子名称: DNA (32-MER), DNA (33-MER), MAGNESIUM ION, ...
著者Lin, Z, Lin, H, Zhang, D, Yuan, C.
登録日2019-04-03
公開日2019-10-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6JRF
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BU of 6jrf by Molmil
Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium
分子名称: CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ...
著者Lin, Z, Lin, H, Zhang, D, Yuan, C.
登録日2019-04-03
公開日2019-10-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
7WOK
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BU of 7wok by Molmil
Crystal structure of HSA soaked with cisplatin for one week
分子名称: Albumin, Cisplatin, PHOSPHATE ION
著者Chen, S.L, Yuan, C, Jiang, L.G, Luo, Z.P, Huang, M.D.
登録日2022-01-21
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystallographic analysis of interaction between cisplatin and human serum albumin: Effect of fatty acid.
Int.J.Biol.Macromol., 216, 2022
7WOJ
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BU of 7woj by Molmil
Crystal structure of HSA-Myr complex soaked with cisplatin for one week
分子名称: Albumin, Cisplatin, MYRISTIC ACID
著者Chen, S.L, Yuan, C, Jiang, L.G, Luo, Z.P, Huang, M.D.
登録日2022-01-21
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Crystallographic analysis of interaction between cisplatin and human serum albumin: Effect of fatty acid.
Int.J.Biol.Macromol., 216, 2022

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