3MHW

The complex crystal Structure of Urokianse and 2-Aminobenzothiazole

Summary for 3MHW

• Entry DOI: 10.2210/pdb3mhw/pdb
• Related: 2NWN 3KID
• Descriptor: Urokinase-type plasminogen activator, SULFATE ION, 1,3-benzothiazol-2-amine, ... (4 entities in total)
• Functional Keywords: hydrolase, blood coagulation, fibrinolysis, plasminogen activation
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P00749
• Total number of polymer chains: 1
• Total formula weight: 28092.95

Authors

Jiang, L.-G.,Yuan, C.,Chen, L.-Q.,Huang, M.-D. (deposition date: 2010-04-09, release date: 2010-04-21, Last modification date: 2023-11-01)

• Primary citation: Jiang, L.-G.,Yu, H.-Y.,Yuan, C.,Wang, J.-D.,Chen, L.-Q.,Meehan, E.J.,Huang, Z.-X.,Huang, M.-D.; Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator; CHIN.J.STRUCT.CHEM., 28:1427-1432, 2009

Experimental method

X-RAY DIFFRACTION (1.45 Å)