2FMX
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![BU of 2fmx by Molmil](/molmil-images/mine/2fmx) | An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+) | 分子名称: | GTP-binding protein SAR1b, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Rao, Y, Bian, C, Yuan, C, Li, Y, Huang, M. | 登録日 | 2006-01-10 | 公開日 | 2006-09-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+) Biochem.Biophys.Res.Commun., 348, 2006
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4XSK
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![BU of 4xsk by Molmil](/molmil-images/mine/4xsk) | Structure of PAItrap, an uPA mutant | 分子名称: | GLYCEROL, SULFATE ION, TRIETHYLENE GLYCOL, ... | 著者 | Gong, L, Proulle, V, Hong, Z, Lin, Z, Liu, M, Yuan, C, Lin, L, Furie, B, Flaumenhaft, R, Andreasen, P, Furie, B, Huang, M. | 登録日 | 2015-01-22 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of PAItrap, an uPA mutant To Be Published
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2FA9
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![BU of 2fa9 by Molmil](/molmil-images/mine/2fa9) | The crystal structure of Sar1[H79G]-GDP provides insight into the coat-controlled GTP hydrolysis in the disassembly of COP II | 分子名称: | GTP-binding protein SAR1b, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Rao, Y, Huang, M, Yuan, C, Bian, C, Hou, X. | 登録日 | 2005-12-07 | 公開日 | 2006-09-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Sar1[H79G]-GDP Which Provides Insight into the Coat-controlled GTP Hydrolysis in the Disassembly of COP II Chin.J.Struct.Chem., 25, 2006
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6XVD
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![BU of 6xvd by Molmil](/molmil-images/mine/6xvd) | Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition | 分子名称: | Urokinase-type plasminogen activator, upain-1-W3F | 著者 | Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G. | 登録日 | 2020-01-21 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases. Biosci.Biotechnol.Biochem., 84, 2020
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2A0T
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![BU of 2a0t by Molmil](/molmil-images/mine/2a0t) | NMR structure of the FHA1 domain of Rad53 in complex with a biological relevant phosphopeptide derived from Madt1 | 分子名称: | Hypothetical 73.8 kDa protein in SAS3-SEC17 intergenic region, residues 301-310, Serine/threonine-protein kinase RAD53 | 著者 | Mahajan, A, Yuan, C, Pike, B.L, Heierhorst, J, Chang, C.-F, Tsai, M.-D. | 登録日 | 2005-06-16 | 公開日 | 2005-11-08 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches J.Am.Chem.Soc., 127, 2005
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6IS8
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![BU of 6is8 by Molmil](/molmil-images/mine/6is8) | Crystal structure of ZmMoc1 D115N mutant in complex with Holliday junction | 分子名称: | DNA (33-MER), MAGNESIUM ION, Monokaryotic chloroplast 1, ... | 著者 | Lin, Z, Lin, H, Zhang, D, Yuan, C. | 登録日 | 2018-11-15 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
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5YIS
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![BU of 5yis by Molmil](/molmil-images/mine/5yis) | Crystal Structure of AnkB LIR/LC3B complex | 分子名称: | Ankyrin-2, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B, ... | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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5YIR
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![BU of 5yir by Molmil](/molmil-images/mine/5yir) | Crystal Structure of AnkB LIR/GABARAP complex | 分子名称: | Ankyrin-2, Gamma-aminobutyric acid receptor-associated protein, NICKEL (II) ION | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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5YIQ
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![BU of 5yiq by Molmil](/molmil-images/mine/5yiq) | Crystal structure of AnkG LIR/LC3B complex | 分子名称: | Ankyrin-3, Microtubule-associated proteins 1A/1B light chain 3B, ZINC ION | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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2O8T
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![BU of 2o8t by Molmil](/molmil-images/mine/2o8t) | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q) in complex with Inhibitors | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, SULFATE ION, ... | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | 登録日 | 2006-12-12 | 公開日 | 2007-12-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors To be Published
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2O8W
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![BU of 2o8w by Molmil](/molmil-images/mine/2o8w) | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors | 分子名称: | 1-phenylguanidine, SULFATE ION, TETRAETHYLENE GLYCOL, ... | 著者 | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | 登録日 | 2006-12-12 | 公開日 | 2007-12-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors To be Published
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3G7N
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![BU of 3g7n by Molmil](/molmil-images/mine/3g7n) | Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3 | 分子名称: | DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ... | 著者 | Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D. | 登録日 | 2009-02-10 | 公開日 | 2010-02-23 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD Proteins, 78, 2010
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4QTH
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![BU of 4qth by Molmil](/molmil-images/mine/4qth) | Crystal structure of anti-uPAR Fab 8B12 | 分子名称: | anti-uPAR antibody, heavy chain, light chain | 著者 | Zhao, B, Yuan, C, Luo, Z, Huang, M. | 登録日 | 2014-07-08 | 公開日 | 2015-02-25 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
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4QTI
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![BU of 4qti by Molmil](/molmil-images/mine/4qti) | Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 | 分子名称: | Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... | 著者 | Zhao, B, Yuan, C, Luo, Z, Huang, M. | 登録日 | 2014-07-08 | 公開日 | 2015-02-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
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3HNB
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![BU of 3hnb by Molmil](/molmil-images/mine/3hnb) | |
3HNY
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![BU of 3hny by Molmil](/molmil-images/mine/3hny) | |
3HOB
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![BU of 3hob by Molmil](/molmil-images/mine/3hob) | |
1DC2
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![BU of 1dc2 by Molmil](/molmil-images/mine/1dc2) | SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, 20 STRUCTURES | 分子名称: | CYCLIN-DEPENDENT KINASE 4 INHIBITOR A (P16INK4A) | 著者 | Byeon, I.-J.L, Li, J, Yuan, C, Tsai, M.-D. | 登録日 | 1999-11-04 | 公開日 | 1999-12-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data. Protein Sci., 9, 2000
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3TKZ
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![BU of 3tkz by Molmil](/molmil-images/mine/3tkz) | Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide | 分子名称: | PROTEIN (RVIpYFVPLNR peptide), Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | 登録日 | 2011-08-29 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
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3TL0
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![BU of 3tl0 by Molmil](/molmil-images/mine/3tl0) | Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide | 分子名称: | RLNpYAQLWHR peptide, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | 登録日 | 2011-08-29 | 公開日 | 2011-09-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
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2N9C
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![BU of 2n9c by Molmil](/molmil-images/mine/2n9c) | NRAS Isoform 5 | 分子名称: | GTPase NRas | 著者 | Markowitz, J, Mal, T.K, Yuan, C, Courtney, N.B, Patel, M, Stiff, A.R, Blachly, J, Walker, C, Eisfeld, A, de la Chapelle, A, Carson III, W.E. | 登録日 | 2015-11-13 | 公開日 | 2016-03-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterization of NRAS isoform 5. Protein Sci., 25, 2016
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4ISO
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![BU of 4iso by Molmil](/molmil-images/mine/4iso) | Crystal Structure of Matriptase in complex with its inhibitor HAI-1 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLUTATHIONE, GLYCEROL, ... | 著者 | Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. | 登録日 | 2013-01-16 | 公開日 | 2013-03-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
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4ISN
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![BU of 4isn by Molmil](/molmil-images/mine/4isn) | Crystal Structure of Matriptase in complex with its inhibitor HAI-1 | 分子名称: | GLUTATHIONE, Kunitz-type protease inhibitor 1, Suppressor of tumorigenicity 14 protein, ... | 著者 | Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. | 登録日 | 2013-01-16 | 公開日 | 2013-03-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
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4IS5
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![BU of 4is5 by Molmil](/molmil-images/mine/4is5) | Crystal Structure of the ligand-free inactive Matriptase | 分子名称: | GLUTATHIONE, GLYCEROL, SULFATE ION, ... | 著者 | Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. | 登録日 | 2013-01-16 | 公開日 | 2013-03-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
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4ISL
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![BU of 4isl by Molmil](/molmil-images/mine/4isl) | Crystal Structure of the inactive Matriptase in complex with its inhibitor HAI-1 | 分子名称: | GLUTATHIONE, GLYCEROL, Kunitz-type protease inhibitor 1, ... | 著者 | Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. | 登録日 | 2013-01-16 | 公開日 | 2013-03-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
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