2VER
 
 | | Structural model for the complex between the Dr adhesins and carcinoembryonic antigen (CEA) | | Descriptor: | AFIMBRIAL ADHESIN AFA-III, ARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | Authors: | Korotkova, N, Yang, Y, Le Trong, I, Cota, E, Demeler, B, Marchant, J, Thomas, W.E, Stenkamp, R.E, Moseley, S.L, Matthews, S. | | Deposit date: | 2007-10-26 | | Release date: | 2008-01-08 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Binding of Dr Adhesins of Escherichia Coli to Carcinoembryonic Antigen Triggers Receptor Dissociation.
Mol.Microbiol., 67, 2008
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3IXT
 | | Crystal Structure of Motavizumab Fab Bound to Peptide Epitope | | Descriptor: | 1,2-ETHANEDIOL, Fusion glycoprotein F1, Motavizumab Fab heavy chain, ... | | Authors: | McLellan, J.S, Chen, M, Kim, A, Yang, Y, Graham, B.S, Kwong, P.D. | | Deposit date: | 2009-09-04 | | Release date: | 2010-01-19 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis of respiratory syncytial virus neutralization by motavizumab.
Nat.Struct.Mol.Biol., 17, 2010
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1QU6
 | | STRUCTURE OF THE DOUBLE-STRANDED RNA-BINDING DOMAIN OF THE PROTEIN KINASE PKR REVEALS THE MOLECULAR BASIS OF ITS DSRNA-MEDIATED ACTIVATION | | Descriptor: | PROTEIN KINASE PKR | | Authors: | Nanduri, S, Carpick, B.W, Yang, Y, Williams, B.R.G, Qin, J. | | Deposit date: | 1999-07-08 | | Release date: | 1999-12-23 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation.
EMBO J., 17, 1998
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5DAY
 | | The structure of NAP1-Related Protein(NRP1) in Arabidopsis | | Descriptor: | CALCIUM ION, NAP1-related protein 1 | | Authors: | Zhu, Y, Rong, L, Yang, Y, Zhang, C, Feng, H.Y, Zheng, L.N, Shen, W.H, Ma, J.B, Dong, A.W. | | Deposit date: | 2015-08-20 | | Release date: | 2016-09-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.329 Å) | | Cite: | The structure of NAP1-Related Protein(NRP1) in Arabidopsis
To Be Published
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5JZV
 | | The structure of D77G hCINAP-ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase isoenzyme 6 | | Authors: | Liu, Y, Yang, Z, Yang, Y, Cai, X, Zheng, X. | | Deposit date: | 2016-05-17 | | Release date: | 2016-08-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.
Nat Commun, 7, 2016
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8HDZ
 | | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form | | Descriptor: | A22 DNA replication processivity factor, E4 uracil-DNA glycosylase, F8 DNA polymerase | | Authors: | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | | Deposit date: | 2022-11-07 | | Release date: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.
Cell Res., 33, 2023
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5E1J
 | | Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | | Descriptor: | BARIUM ION, CALCIUM ION, Two pore calcium channel protein 1 | | Authors: | Guo, J, Zeng, W, Chen, Q, Lee, C, Chen, L, Yang, Y, Jiang, Y. | | Deposit date: | 2015-09-29 | | Release date: | 2015-12-16 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.308 Å) | | Cite: | Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana.
Nature, 531, 2016
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1T28
 | | High resolution structure of a picornaviral internal cis-acting replication element | | Descriptor: | 34-MER | | Authors: | Thiviyanathan, V, Yang, Y, Kaluarachchi, K, Reynbrand, R, Gorenstein, D.G, Lemon, S.M. | | Deposit date: | 2004-04-20 | | Release date: | 2004-08-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | High resolution structure of a picornaviral internal cis-acting replication element(cre).
Proc.Natl.Acad.Sci.USA, 101, 2004
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6PQY
 | | Cryo-EM structure of HzTransib/TIR DNA transposon end complex (TEC) | | Descriptor: | DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*G)-3'), Putative DNA-mediated transposase | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-10 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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6PR5
 | | Cryo-EM structure of HzTransib strand transfer complex (STC) | | Descriptor: | DNA (30-MER), DNA (39-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*TP*CP*A)-3'), ... | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-10 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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6IW7
 | | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease | | Descriptor: | (2S)-2-benzamido-4-methyl-pentanoic acid, 4-[(4-fluoro-2-methyl-3H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline, ATP-dependent Clp protease proteolytic subunit 1, ... | | Authors: | Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. | | Deposit date: | 2018-12-04 | | Release date: | 2020-01-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.692121 Å) | | Cite: | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease
To Be Published
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6PQN
 | | Crystal structure of HzTransib transposase | | Descriptor: | GLYCEROL, PHOSPHATE ION, Putative DNA-mediated transposase, ... | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-09 | | Release date: | 2019-10-09 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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6PQU
 | | Cryo-EM structure of HzTransib/nicked TIR substrate DNA pre-reaction complex (PRC) | | Descriptor: | DNA (5'-D(P*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA-mediated transposase, ... | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-10 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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6PQX
 | | Cryo-EM structure of HzTransib/nicked TIR substrate DNA hairpin forming complex (HFC) | | Descriptor: | CALCIUM ION, DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), ... | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-10 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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6PQR
 | | Cryo-EM structure of HzTransib/intact TIR substrate DNA pre-reaction complex (PRC) | | Descriptor: | DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*GP*AP*GP*AP*TP*CP*TP*AP*G)-3'), DNA-mediated transposase, ... | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-09 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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8HOY
 | | Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram | | Descriptor: | DNA polymerase, DNA polymerase processivity factor component A20, E4R | | Authors: | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | | Deposit date: | 2022-12-11 | | Release date: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structure of DNA replication machinery from human monkeypox virus
To Be Published
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3O45
 | | Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope | | Descriptor: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F 101F Fab heavy chain, Mouse monoclonal antibody 101F 101F Fab light chain, ... | | Authors: | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | | Deposit date: | 2010-07-26 | | Release date: | 2010-10-13 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.872 Å) | | Cite: | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
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3O41
 | | Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope | | Descriptor: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F Fab heavy chain, Mouse monoclonal antibody 101F Fab light chain, ... | | Authors: | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | | Deposit date: | 2010-07-26 | | Release date: | 2010-10-13 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
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3BQO
 | | Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex | | Descriptor: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 1 | | Authors: | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | Deposit date: | 2007-12-20 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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3OIQ
 | | Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA polymerase alpha Pol1 | | Descriptor: | Cell division control protein 13, DNA polymerase alpha catalytic subunit A | | Authors: | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | | Deposit date: | 2010-08-19 | | Release date: | 2010-11-03 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
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3OIP
 | | Crystal structure of Yeast telomere protein Cdc13 OB1 | | Descriptor: | Cell division control protein 13 | | Authors: | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | | Deposit date: | 2010-08-19 | | Release date: | 2010-11-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.504 Å) | | Cite: | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
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2EEM
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3BUA
 | | Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex | | Descriptor: | DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2 | | Authors: | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | Deposit date: | 2008-01-02 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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3R0M
 | | Crystal structure of anti-HIV llama VHH antibody A12 | | Descriptor: | Llama VHH A12, SULFATE ION | | Authors: | Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D. | | Deposit date: | 2011-03-08 | | Release date: | 2012-03-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
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3BU8
 | | Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex | | Descriptor: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 | | Authors: | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | Deposit date: | 2008-01-02 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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