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8HOY

Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram

Summary for 8HOY
Entry DOI10.2210/pdb8hoy/pdb
EMDB information34684 34927
DescriptorDNA polymerase, DNA polymerase processivity factor component A20, E4R (3 entities in total)
Functional Keywordsdna replication machinery, dna polymerase, b-family dna polymerase, uracil-dna glycosylase, mpxv, orthopoxvirus, poxviridae, dna processivity factor, viral protein
Biological sourceMonkeypox virus
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Total number of polymer chains3
Total formula weight197128.79
Authors
Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Yang, B.,Zhang, Z.,Dong, C. (deposition date: 2022-12-11, release date: 2023-12-13)
Primary citationXu, Y.X.,Wu, Y.Q.,Zhang, Y.Y.,Fan, R.X.,Yang, Y.X.,Li, D.Y.,Yang, B.,Zhang, Z.Y.,Dong, C.J.
Structure of DNA replication machinery from human monkeypox virus
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.76 Å)
Structure validation

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