4PO5
 
 | | Crystal structure of allophycocyanin B from Synechocystis PCC 6803 | | Descriptor: | Allophycocyanin beta chain, Allophycocyanin subunit alpha-B, PHYCOCYANOBILIN, ... | | Authors: | Pang, P.P, Dong, L.L, Sun, Y.F, Zeng, X.L, Ding, W.L, Scheer, H, Yang, X, Zhao, K.H. | | Deposit date: | 2014-02-24 | | Release date: | 2014-10-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | The structure of allophycocyanin B from Synechocystis PCC 6803 reveals the structural basis for the extreme redshift of the terminal emitter in phycobilisomes.
Acta Crystallogr.,Sect.D, 70, 2014
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5D2N
 | | Crystal structure of C25-NLV-HLA-A2 complex | | Descriptor: | ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ... | | Authors: | Mariuzza, R.A, Yang, X. | | Deposit date: | 2015-08-05 | | Release date: | 2015-10-07 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
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3ULF
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3UE6
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3UIU
 | | Crystal structure of Apo-PKR kinase domain | | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase | | Authors: | Li, F, Li, S, Yang, X, Shen, Y, Zhang, T. | | Deposit date: | 2011-11-06 | | Release date: | 2012-11-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.903 Å) | | Cite: | Crystal structure of Apo-PKR kinase domain
TO BE PUBLISHED
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5T4D
 | | Cryo-EM structure of Polycystic Kidney Disease protein 2 (PKD2), residues 198-703 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, hPKD:198-703, Polycystin-2 | | Authors: | Shen, P.S, Yang, X, DeCaen, P.G, Liu, X, Bulkley, D, Clapham, D.E, Cao, E. | | Deposit date: | 2016-08-29 | | Release date: | 2016-11-02 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.
Cell, 167, 2016
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8K6L
 | | Cryo-EM structure of human OATP1B1 in complex with DCF | | Descriptor: | 2',7'-bis(chloranyl)-3',6'-bis(oxidanyl)spiro[2-benzofuran-3,9'-xanthene]-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Shan, Z, Yang, X, Zhang, Y. | | Deposit date: | 2023-07-25 | | Release date: | 2023-09-13 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023
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4O4S
 | | Crystal structure of phycobiliprotein lyase CpcT complexed with phycocyanobilin (PCB) | | Descriptor: | PHYCOCYANOBILIN, Phycocyanobilin lyase CpcT | | Authors: | Zhou, W, Ding, W.-L, Zeng, X.-l, Dong, L.-L, Zhao, B, Zhou, M, Scheer, H, Zhao, K.-H, Yang, X. | | Deposit date: | 2013-12-19 | | Release date: | 2014-08-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure and Mechanism of the Phycobiliprotein Lyase CpcT.
J.Biol.Chem., 289, 2014
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3Q5M
 | | Crystal structure of Escherichia coli BamD | | Descriptor: | IODIDE ION, UPF0169 lipoprotein yfiO | | Authors: | Dong, C, Hou, H, Yang, X, Dong, Y, Shen, Y. | | Deposit date: | 2010-12-28 | | Release date: | 2011-12-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Structure of Escherichia coli BamD and its functional implications in outer membrane protein assembly
Acta Crystallogr.,Sect.D, 68, 2012
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4O4O
 | | Crystal structure of phycobiliprotein lyase CpcT | | Descriptor: | MAGNESIUM ION, Phycocyanobilin lyase CpcT | | Authors: | Zhou, W, Ding, W.-L, Zeng, X.-l, Dong, L.-L, Zhao, B, Zhou, M, Scheer, H, Zhao, K.-H, Yang, X. | | Deposit date: | 2013-12-19 | | Release date: | 2014-08-06 | | Last modified: | 2014-10-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and Mechanism of the Phycobiliprotein Lyase CpcT.
J.Biol.Chem., 289, 2014
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6D1W
 | | human PKD2 F604P mutant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | | Authors: | Zheng, W, Yang, X, Bulkley, D, Chen, X.Z, Cao, E. | | Deposit date: | 2018-04-12 | | Release date: | 2018-06-27 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
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3Q54
 | | Crystal structure of Escherichia coli BamB | | Descriptor: | Outer membrane assembly lipoprotein YfgL | | Authors: | Dong, C, Hou, H, Yang, X. | | Deposit date: | 2010-12-27 | | Release date: | 2012-05-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.004 Å) | | Cite: | Structure of Escherichia coli BamB and its interaction with POTRA domains of BamA.
Acta Crystallogr.,Sect.D, 68, 2012
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5THL
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5THH
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5ZOL
 | | Crystal structure of a three sites mutantion of FSAA complexed with HA and product | | Descriptor: | (3S,4S)-3,4-dihydroxy-4-(thiophen-2-yl)butan-2-one, 1-hydroxypropan-2-one, CHLORIDE ION, ... | | Authors: | Wu, L, Yang, X.H, Yu, H.W, Zhou, J.H. | | Deposit date: | 2018-04-13 | | Release date: | 2019-06-12 | | Last modified: | 2020-07-22 | | Method: | X-RAY DIFFRACTION (2.172 Å) | | Cite: | The engineering of decameric d-fructose-6-phosphate aldolase A by combinatorial modulation of inter- and intra-subunit interactions.
Chem.Commun.(Camb.), 56, 2020
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1Y2I
 | | Crystal Structure of MCSG Target APC27401 from Shigella flexneri | | Descriptor: | Hypothetical Protein S0862 | | Authors: | Brunzelle, J.S, Minasov, G, Yang, X, Shuvalova, L, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2004-11-22 | | Release date: | 2005-01-04 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of MCSG Target APC27401 from Shigella flexneri
To be Published
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6J44
 | | Crystal structure of the redefined DNA-binding domain of human XPA | | Descriptor: | DNA repair protein complementing XP-A cells, ZINC ION | | Authors: | Lian, F.M, Yang, X, Yang, W, Jiang, Y.L, Qian, C. | | Deposit date: | 2019-01-07 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural characterization of the redefined DNA-binding domain of human XPA.
Biochem.Biophys.Res.Commun., 514, 2019
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6AKI
 | | Calcium release-activated calcium channel protein 1, P288L mutant | | Descriptor: | CHLORIDE ION, Calcium release-activated calcium channel protein 1 | | Authors: | Liu, X, Wu, G, Yang, X, Shen, Y. | | Deposit date: | 2018-09-01 | | Release date: | 2019-03-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (4.496 Å) | | Cite: | Calcium release-activated calcium channel protein 1, P288L mutant
To Be Published
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7E5Y
 | | Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD | | Descriptor: | 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1 | | Authors: | Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M. | | Deposit date: | 2021-02-21 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.59 Å) | | Cite: | Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries.
Cell Discov, 7, 2021
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4O9B
 | | The Structure of CC1-IH in human STIM1. | | Descriptor: | CADMIUM ION, Stromal interaction molecule 1 | | Authors: | Cui, B, Yang, X, Li, S, Shen, Y. | | Deposit date: | 2014-01-02 | | Release date: | 2014-01-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | The inhibitory helix controls the intramolecular conformational switching of the C-terminus of STIM1.
Plos One, 8, 2013
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8SP0
 | | Symmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid | | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2023-05-01 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
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8SQU
 | | Monomeric MapSPARTA bound with guide RNA and target DNA hybrid | | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2023-05-04 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
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8SP3
 | | Asymmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid | | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2023-05-01 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
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8SPO
 | | Tetramerized activation of MapSPARTA bound with NAD+ | | Descriptor: | MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain-containing protein, ... | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2023-05-03 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
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5XGH
 | | Crystal structure of PI3K complex with an inhibitor | | Descriptor: | 3-[(4-fluorophenyl)methylamino]-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | | Authors: | Song, K, Yang, X, Zhao, Y, Jian, Z. | | Deposit date: | 2017-04-13 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound.
Sci Rep, 7, 2017
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