8SP3
Asymmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid
Summary for 8SP3
Entry DOI | 10.2210/pdb8sp3/pdb |
EMDB information | 40673 |
Descriptor | TIR-APAZ, short pAgo, guide RNA, ... (5 entities in total) |
Functional Keywords | short prokaryotic argonaute, oligomerization, tir, nadase activity, bacterial immune system, mapsparta, immune system |
Biological source | Maribacter polysiphoniae More |
Total number of polymer chains | 8 |
Total formula weight | 251164.12 |
Authors | Shen, Z.F.,Yang, X.Y.,Fu, T.M. (deposition date: 2023-05-01, release date: 2023-08-23, Last modification date: 2023-09-20) |
Primary citation | Shen, Z.,Yang, X.Y.,Xia, S.,Huang, W.,Taylor, D.J.,Nakanishi, K.,Fu, T.M. Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621:154-161, 2023 Cited by PubMed: 37494956DOI: 10.1038/s41586-023-06456-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.52 Å) |
Structure validation
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