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PDB: 235 results

7RYV
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Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
Descriptor: Ab1573 Fab heavy chain, Ab1573 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYU
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Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
Descriptor: Ab1303 Fab heavy chain, Ab1303 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
6U0N
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BU of 6u0n by Molmil
Asymmetrically open conformational state (Class II) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2019-08-14
Release date:2019-12-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Nat.Struct.Mol.Biol., 26, 2019
6U0L
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Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2019-08-14
Release date:2019-12-11
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Nat.Struct.Mol.Biol., 26, 2019
7TFN
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BU of 7tfn by Molmil
Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2022-01-06
Release date:2022-01-19
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
1QBZ
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BU of 1qbz by Molmil
THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, MERCURY (II) ION, ...
Authors:Yang, Z.-N, Mueser, T.C, Kaufman, J, Stahl, S.J, Wingfield, P.T, Hyde, C.C.
Deposit date:1999-04-28
Release date:1999-05-17
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution.
J.Struct.Biol., 126, 1999
7TFO
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BU of 7tfo by Molmil
Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2022-01-06
Release date:2022-01-26
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
8D5C
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BU of 8d5c by Molmil
anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4
Descriptor: CG10 Fab heavy chain, CG10 Fab light chain, Envelope glycoprotein gp160, ...
Authors:Yang, Z, Bjorkman, P.J, Gershoni, J.M.
Deposit date:2022-06-04
Release date:2022-11-16
Last modified:2023-01-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers.
J.Virol., 96, 2022
1N86
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BU of 1n86 by Molmil
Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands.
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ...
Authors:Yang, Z, Pandi, L, Doolittle, R.F.
Deposit date:2002-11-19
Release date:2003-01-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Biochemistry, 41, 2002
1PJL
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BU of 1pjl by Molmil
Crystal structure of human m-NAD-ME in ternary complex with NAD and Lu3+
Descriptor: LUTETIUM (III) ION, NAD-dependent malic enzyme, mitochondrial, ...
Authors:Yang, Z, Batra, R, Floyd, D.L, Hung, H.-C, Chang, G.-G, Tong, L.
Deposit date:2003-06-03
Release date:2003-06-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Potent and competitive inhibition of malic enzymes by lanthanide ions
Biochem.Biophys.Res.Commun., 274, 2000
8D54
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BU of 8d54 by Molmil
anti HIV gp120/CD4 complex antibody CG10 Fab
Descriptor: CG10 Fab heavy chain, CG10 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2022-06-03
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers.
J.Virol., 96, 2022
3IT8
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BU of 3it8 by Molmil
Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2L protein, Tumor necrosis factor
Authors:Yang, Z, West Jr, A.P, Bjorkman, P.J.
Deposit date:2009-08-27
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of TNFalpha complexed with a poxvirus MHC-related TNF binding protein
Nat.Struct.Mol.Biol., 16, 2009
1C1A
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BU of 1c1a by Molmil
CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE
Descriptor: RSV INTEGRASE
Authors:Yang, Z.-N, Mueser, T.C, Bushman, F.D, Hyde, C.C.
Deposit date:1999-07-21
Release date:2000-03-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase.
J.Mol.Biol., 296, 2000
1C0M
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BU of 1c0m by Molmil
CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE
Descriptor: PROTEIN (INTEGRASE)
Authors:Yang, Z.-N, Mueser, T.C, Bushman, F.D, Hyde, C.C.
Deposit date:1999-07-16
Release date:2000-03-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase.
J.Mol.Biol., 296, 2000
1M1J
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BU of 1m1j by Molmil
Crystal structure of native chicken fibrinogen with two different bound ligands
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yang, Z, Kollman, J.M, Pandi, L, Doolittle, R.F.
Deposit date:2002-06-19
Release date:2002-06-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution
Biochemistry, 40, 2001
1TEH
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BU of 1teh by Molmil
STRUCTURE OF HUMAN LIVER CHICHI ALCOHOL DEHYDROGENASE (A GLUTATHIONE-DEPENDENT FORMALDEHYDE DEHYDROGENASE)
Descriptor: HUMAN CHICHI ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Yang, Z.-N, Hurley, T.D.
Deposit date:1996-02-05
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human chi chi alcohol dehydrogenase: a glutathione-dependent formaldehyde dehydrogenase.
J.Mol.Biol., 265, 1997
1LWU
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BU of 1lwu by Molmil
Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yang, Z, Spraggon, G, Pandi, L, Everse, S.J, Riley, M, Doolittle, R.F.
Deposit date:2002-06-03
Release date:2002-08-23
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.
Biochemistry, 41, 2002
1N8E
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BU of 1n8e by Molmil
Fragment Double-D from Human Fibrin
Descriptor: Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain
Authors:Yang, Z, Pandi, L, Doolittle, R.F.
Deposit date:2002-11-20
Release date:2003-01-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
1N73
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BU of 1n73 by Molmil
Fibrin D-Dimer, Lamprey complexed with the PEPTIDE LIGAND: GLY-HIS-ARG-PRO-AMIDE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin alpha-1 chain, ...
Authors:Yang, Z, Pandi, L, Doolittle, R.F.
Deposit date:2002-11-12
Release date:2003-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface
Biochemistry, 41, 2002
1Q0S
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BU of 1q0s by Molmil
Binary Structure of T4DAM with AdoHcy
Descriptor: DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yang, Z, Horton, J.R, Zhou, L, Zhang, X.J, Dong, A, Zhang, X, Schlagman, S.L, Kossykh, V, Hattman, S, Cheng, X.
Deposit date:2003-07-17
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
1GQ2
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BU of 1gq2 by Molmil
Malic Enzyme from Pigeon Liver
Descriptor: CHLORIDE ION, MALIC ENZYME, MANGANESE (II) ION, ...
Authors:Yang, Z, Zhang, H, Liang, T.
Deposit date:2001-11-19
Release date:2002-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of the Pigeon Cytosolic Nadp+ -Dependent Malic Enzyme
Protein Sci., 11, 2002
1GZ4
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BU of 1gz4 by Molmil
molecular mechanism of the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, FUMARIC ACID, MANGANESE (II) ION, ...
Authors:Yang, Z, Lanks, C.W, Tong, L.
Deposit date:2002-05-15
Release date:2002-07-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Mechanism for the Regulation of Human Mitochondrial Nad(P)(+)-Dependent Malic Enzyme by ATP and Fumarate
Structure, 10, 2002
1Q0T
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BU of 1q0t by Molmil
Ternary Structure of T4DAM with AdoHcy and DNA
Descriptor: 5'-D(*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*T)-3', DNA adenine methylase, IODIDE ION, ...
Authors:Yang, Z, Horton, J.R, Zhou, L, Zhang, X.J, Dong, A, Zhang, X, Schlagman, S.L, Kossykh, V, Hattman, S, Cheng, X.
Deposit date:2003-07-17
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
7TLE
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BU of 7tle by Molmil
Crystal Structure of small molecule beta-lactone 1 covalently bound to K-Ras(G12S)
Descriptor: (3R,4R)-1-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]-3-hydroxypiperidine-4-carbaldehyde, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ziyang, Z, Guiley, K.Z, Shokat, K.M.
Deposit date:2022-01-18
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98716748 Å)
Cite:Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S).
Nat.Chem.Biol., 18, 2022
7TLK
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Crystal Structure of K-Ras(G12S)
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Ziyang, Z, Guiley, K.Z, Shokat, K.M.
Deposit date:2022-01-18
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71102226 Å)
Cite:Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S).
Nat.Chem.Biol., 18, 2022

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