3QFP
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3QML
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![BU of 3qml by Molmil](/molmil-images/mine/3qml) | The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor | 分子名称: | 78 kDa glucose-regulated protein homolog, MAGNESIUM ION, Nucleotide exchange factor SIL1, ... | 著者 | Yan, M, Li, J.Z, Sha, B.D. | 登録日 | 2011-02-04 | 公開日 | 2011-06-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor. Biochem.J., 438, 2011
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3QFU
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![BU of 3qfu by Molmil](/molmil-images/mine/3qfu) | Crystal structure of Yeast Hsp70 (Bip/kar2) complexed with ADP | 分子名称: | 78 kDa glucose-regulated protein homolog, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Yan, M, Li, J.Z, Sha, B.D. | 登録日 | 2011-01-22 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor. Biochem.J., 438, 2011
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8HEF
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![BU of 8hef by Molmil](/molmil-images/mine/8hef) | The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 | 分子名称: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL | 著者 | Yan, M, Zhang, H. | 登録日 | 2022-11-08 | 公開日 | 2023-04-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2. Antiviral Res., 213, 2023
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6PIH
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![BU of 6pih by Molmil](/molmil-images/mine/6pih) | Hexameric ArnA cryo-EM structure | 分子名称: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | 著者 | Yang, M, Gehring, K. | 登録日 | 2019-06-26 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements. J.Struct.Biol., 208, 2019
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4IKG
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1K7E
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![BU of 1k7e by Molmil](/molmil-images/mine/1k7e) | CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID | 分子名称: | N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A. | 登録日 | 2001-10-19 | 公開日 | 2002-07-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase. J.Biol.Chem., 277, 2002
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6PIK
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![BU of 6pik by Molmil](/molmil-images/mine/6pik) | Tetrameric cryo-EM ArnA | 分子名称: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | 著者 | Yang, M, Gehring, K. | 登録日 | 2019-06-26 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements. J.Struct.Biol., 208, 2019
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6R4V
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![BU of 6r4v by Molmil](/molmil-images/mine/6r4v) | Crystal structure of human geranylgeranyl diphosphate synthase bound to ibandronate | 分子名称: | GLYCEROL, Geranylgeranyl pyrophosphate synthase, IBANDRONATE, ... | 著者 | Lisnyansky, M, Giladi, M, Haitin, Y. | 登録日 | 2019-03-24 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Metal Coordination Is Crucial for Geranylgeranyl Diphosphate Synthase-Bisphosphonate Interactions: A Crystallographic and Computational Analysis. Mol.Pharmacol., 96, 2019
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2UXN
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![BU of 2uxn by Molmil](/molmil-images/mine/2uxn) | Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation | 分子名称: | CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H. | 登録日 | 2007-03-28 | 公開日 | 2007-05-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation. Nat.Struct.Mol.Biol., 14, 2007
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2UXX
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![BU of 2uxx by Molmil](/molmil-images/mine/2uxx) | Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct | 分子名称: | CHLORIDE ION, FAD-trans-2-Phenylcyclopropylamine Adduct, GLYCEROL, ... | 著者 | Yang, M, Culhane, J.C, Machius, M, Cole, P.A, Yu, H. | 登録日 | 2007-03-30 | 公開日 | 2007-08-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine. Biochemistry, 46, 2007
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6G31
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![BU of 6g31 by Molmil](/molmil-images/mine/6g31) | Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y bound to zoledronate | 分子名称: | Geranylgeranyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID | 著者 | Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y. | 登録日 | 2018-03-24 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures. Mol. Pharmacol., 94, 2018
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6G32
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![BU of 6g32 by Molmil](/molmil-images/mine/6g32) | Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y | 分子名称: | GLYCEROL, Geranylgeranyl pyrophosphate synthase | 著者 | Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y. | 登録日 | 2018-03-24 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.281 Å) | 主引用文献 | Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures. Mol. Pharmacol., 94, 2018
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2VFX
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![BU of 2vfx by Molmil](/molmil-images/mine/2vfx) | Structure of the Symmetric Mad2 Dimer | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | 著者 | Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X. | 登録日 | 2007-11-05 | 公開日 | 2008-03-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol., 6, 2008
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4BUZ
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![BU of 4buz by Molmil](/molmil-images/mine/4buz) | SIR2 COMPLEX STRUCTURE MIXTURE OF EX-527 INHIBITOR AND REACTION PRODUCTS OR OF REACTION SUBSTRATES P53 PEPTIDE AND NAD | 分子名称: | (1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide, 1,2-ETHANEDIOL, 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, ... | 著者 | Weyand, M, Lakshminarasimhan, M, Gertz, M, Steegborn, C. | 登録日 | 2013-06-24 | 公開日 | 2013-07-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Ex-527 Inhibits Sirtuins by Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism Proc.Natl.Acad.Sci.USA, 110, 2013
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8ANC
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8ANB
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2YW9
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7NXZ
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2ZIY
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3T9N
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![BU of 3t9n by Molmil](/molmil-images/mine/3t9n) | Crystal structure of a membrane protein | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel | 著者 | Yang, M, Zhang, X, Ge, J, Wang, J. | 登録日 | 2011-08-03 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.456 Å) | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance Proc.Natl.Acad.Sci.USA, 109, 2012
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4BGC
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1QI9
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![BU of 1qi9 by Molmil](/molmil-images/mine/1qi9) | X-RAY SIRAS STRUCTURE DETERMINATION OF A VANADIUM-DEPENDENT HALOPEROXIDASE FROM ASCOPHYLLUM NODOSUM AT 2.0 A RESOLUTION | 分子名称: | VANADATE ION, Vanadium-dependent bromoperoxidase | 著者 | Weyand, M, Hecht, H.-J, Kiess, M, Liaud, M.F, Vilter, H, Schomburg, D. | 登録日 | 1999-06-10 | 公開日 | 2000-06-10 | 最終更新日 | 2023-06-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution. J.Mol.Biol., 293, 1999
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2LQJ
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4NQJ
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![BU of 4nqj by Molmil](/molmil-images/mine/4nqj) | Structure of coiled-coil domain | 分子名称: | DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69 | 著者 | Yang, M, Li, Y. | 登録日 | 2013-11-25 | 公開日 | 2014-05-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Structural insights into the TRIM family of ubiquitin E3 ligases. Cell Res., 24, 2014
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