7JZK
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7JZ1
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4PLM
| Crystal Structure of Chicken Netrin-1 (LN-LE3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Xu, K, Nikolov, D.B. | Deposit date: | 2014-05-18 | Release date: | 2014-06-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science, 344, 2014
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4PLN
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7LKG
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7LKB
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4YN0
| Crystal structure of APP E2 domain in complex with DR6 CRD domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amyloid beta A4 protein, MAGNESIUM ION, ... | Authors: | Xu, K, Nikolov, D. | Deposit date: | 2015-03-08 | Release date: | 2015-04-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation. Genes Dev., 29, 2015
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6CMG
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6CMI
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6MQC
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6MQR
| Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519) | Descriptor: | CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ... | Authors: | Xu, K, Wang, Y, Kwong, P.D. | Deposit date: | 2018-10-10 | Release date: | 2019-07-31 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
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6N16
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6MQE
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6MQS
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6MQM
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5EVM
| Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MALONATE ION, ... | Authors: | Xu, K, Nikolov, D.B. | Deposit date: | 2015-11-20 | Release date: | 2015-12-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.367 Å) | Cite: | Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. Plos Pathog., 11, 2015
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7KHF
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7KFK
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5UTY
| Crystal Structure of a Stabilized DS-SOSIP.mut4 BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, N300M, N302M, T320L in Complex with Human Antibodies PGT122 and 35O22 at 4.1 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ... | Authors: | Xu, K, Chuang, G.-Y, Pancera, M, Kwong, P.D. | Deposit date: | 2017-02-15 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.412 Å) | Cite: | Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. J. Virol., 91, 2017
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5T0K
| Structure of G9a SET-domain with H3K9M mutant peptide and SAM | Descriptor: | H3K9 mutant peptide, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... | Authors: | Xu, K, Tong, L. | Deposit date: | 2016-08-16 | Release date: | 2016-10-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading. Elife, 5, 2016
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5T0M
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5ECD
| Structure of the Shigella flexneri VapC mutant D98N crystal form 1 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC | Authors: | Xu, K. | Deposit date: | 2015-10-20 | Release date: | 2016-02-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri. Proteins, 84, 2016
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3D11
| Crystal Structures of the Nipah G Attachment Glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ... | Authors: | Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B. | Deposit date: | 2008-05-02 | Release date: | 2008-08-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.306 Å) | Cite: | Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc.Natl.Acad.Sci.USA, 105, 2008
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3D12
| Crystal Structures of Nipah Virus G Attachment Glycoprotein in Complex with its Receptor Ephrin-B3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-B3, ... | Authors: | Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B. | Deposit date: | 2008-05-02 | Release date: | 2008-08-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.005 Å) | Cite: | Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc.Natl.Acad.Sci.USA, 105, 2008
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7XM5
| Keap1 Kelch domain (residues 322-609) in complex with 6i | Descriptor: | Kelch-like ECH-associated protein 1, N-[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]-3-morpholin-4-yl-propanamide | Authors: | Xu, K. | Deposit date: | 2022-04-24 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallography-Guided Optimizations of the Keap1-Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides. J.Med.Chem., 65, 2022
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